A5086136399- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Renal Diseases and Glomerulopathies
- Systemic Lupus Erythematosus Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Inflammatory Myopathies and Dermatomyositis
- Sarcoidosis and Beryllium Toxicity Research
- Metabolism and Genetic Disorders
- Salivary Gland Disorders and Functions
- Urticaria and Related Conditions
- IgG4-Related and Inflammatory Diseases
- Ultrasound in Clinical Applications
- Engine and Fuel Emissions
- Rheumatoid Arthritis Research and Therapies
- Neurological and metabolic disorders
- Skin Diseases and Diabetes
- Ultrasound and Hyperthermia Applications
- Otitis Media and Relapsing Polychondritis
- Autoimmune Bullous Skin Diseases
- Renal Transplantation Outcomes and Treatments
- Platelet Disorders and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Immunodeficiency and Autoimmune Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Agriculture, Plant Science, Crop Management
Gdańsk Medical University
2015-2024
University of Gdańsk
1997-2017
Wroclaw University of Environmental and Life Sciences
2014-2016
Institute of Agricultural Engineering
2016
University of Life Sciences in Lublin
2016
University Clinical Centre
2014
Wojskowy Instytut Medyczny
1992-1998
Ottawa Fertility Centre
1967
Patients with a diagnosed systemic connective tissue disease require regular monitoring from the point of view interstitial lung disease. The main aim this work is description criteria for pulmonary fibrosis and degree severity during course through TLU (transthoracic ultrasound).52 patients diffuse were qualified research, together 50 volunteers in control group. both groups over 18 years age sexes. results underwent statistical analysis compared to High-Resolution Computed Tomography...
Sympathetic activation may contribute to both cardiovascular morbidity and the progression of chronic kidney disease. The role chemoreceptors in determining sympathetic nerve discharge patients with renal failure (CRF) is unknown. We tested hypothesis that tonic excitatory chemoreceptor afferents contributes elevated activity CRF.Utilizing a double-blind, randomized, vehicle-controlled design, we examined effects chemoreflex deactivation on muscle (MSNA). compared breathing 100% oxygen for...
<b>Introduction</b>: Granulomatosis with polyangiitis (GPA) is a rare, ANCA-associated, systemic disease characterized by necrotizing small and medium vessel vasculitis of unknown etiology associated granulomatous inflammation affecting the renal, pulmonary, upper airways, ocular systems other tissues. Histological proof granulomatosis can be obtained biopsy clinically involved sites. The main purpose this study was to examine histopathological changes in non-renal biopsies from...
This study aimed to evaluate changes in plasma amino acid and nicotinamide metabolites concentrations rheumatoid arthritis (RA) a search for potential biomarkers of the disease activity effect treatment. Analysis metabolite patterns with liquid chromatography/mass spectrometry revealed specific RA as well correlations clinical parameters. Combined concentration parameter calculated [aspartic acid] + [threonine] [tryptophan] − [histidine] [phenylalanine] offered strongest correlation (p <...
Abstract Objectives Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background possible complications from peripheral (PNS) and central nervous system (CNS). The aim of this study was to assess the prevalence describe phenotype neuropathies in patients SS. Materials & Methods We studied fifty primary for involvement. All underwent neurological rheumatological examination followed by nerve conduction studies (NCS) nine nerves. Results Thirty‐six (72%)...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Masiak A, Zdrojewski Ł, Z, Bułło-Piontecka B, Rutkowski B. Gastrointestinal tract involvement in granulomatosis with polyangiitis. Gastroenterology Review/Przegląd Gastroenterologiczny. 2016;11(4):270-275. doi:10.5114/pg.2016.57887. APA Masiak, A., Zdrojewski, Ł., Z., Bułło-Piontecka, B., & Rutkowski, (2016). Gastroenterologiczny, 11(4), 270-275. https://doi.org/10.5114/pg.2016.57887 Chicago Anna, Łukasz...
The renal benefits of agents inhibiting the renin-angiotensin-aldosterone system in transplant recipients, i.e. preventing development chronic graft nephropathy, are supposed but not finally proven. In a double-blind, placebo-controlled, cross-over study, we evaluated influence losartan on surrogate markers tubular injury, urine excretion transforming growth factor beta-1 (TGF-beta1) and amino-terminal propeptide type III procollagen (PIIINP) 16 patients after transplantation. received...
<b>Objectives</b>: Inflammatory myopathies are a group of idiopathic, heterogeneous systemic diseases affecting predominantly skeletal muscles, though they can also involve the skin and internal organs. The association between cancer idiopathic inflammatory myopathies, particularly dermatomyositis, which is termed cancer-associated myositis (CAM), has been reported in medical literature. A newly described autoantibody to 155-kDa nuclear protein, identified as transcription...
Abstract Mixed connective tissue disease ( MCTD ) is a systemic autoimmune disease, originally defined as inflammatory syndrome with overlapping features of lupus erythematosus SLE ), rheumatoid arthritis RA polymyositis/dermatomyositis PM / DM and sclerosis SSc characterized by the presence antibodies against components U1 small nuclear ribonucleoprotein U1snRNP ). The aim study was to assess frequency (high‐resolution‐typed) DRB1 alleles in cohort Polish patients n = 103). Identification...
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare small to medium-size vessel systemic diseases. As their clinical picture, organ involvement, and factors influencing outcome may differ between countries geographical areas, we decided describe a large cohort of Polish AAV patients coming from several referral centers—members the Scientific Consortium Vasculitis Registry (POLVAS). We conducted systematic multicenter retrospective study adult diagnosed with Jan...
The aim of this study is to present the treatment modalities and associated side effects in a Polish nation-wide ANCA-associated vasculitides (AAV) patients' cohort. Retrospective analysis patients diagnosed with AAV between 1990 2016, included POLVAS registry was performed. Standard descriptive statistic methods were used an emphasis on modalities. There 625 study: 417 cases granulomatosis polyangiitis (GPA; 66.7%), 106 microscopic (MPA; 17.0%) 102 eosinophilic (EGPA; 16.3%). mean age at...
To characterize the eosinophilic granulomatosis with polyangiitis (EGPA) population from POLVAS registry depending on ANCA status and diagnosis onset, including their comparison (GPA) subset elevated blood eosinophilia (min. 400/
Background. The renoprotective effects of agents inhibiting the renin-angiotensin system in renal transplant recipients have been supposed but not finally proven. To shed more light on this issue, we performed a double-blind, placebo-controlled, crossover study to evaluate influence AT-1 angiotensin II receptor blocker, losartan, surrogate marker kidney injury, albuminuria, patients after transplantation. safety therapy was also evaluated. Methods. Fourteen 16 (nine male, five female), age...
Suicidal ideation is observed in patients with systemic lupus erythematosus (SLE). No study on this notable phenomenon neuropsychiatric SLE (NPSLE) available so far.Participants were 53 consecutive outpatients NPSLE (48 women; mean age 43.8 years) diagnosed according to the American College of Rheumatology nomenclature for syndromes. A Neuropsychiatric Questionnaire (NP-Q) concerning 45 neurological, cognitive and psychiatric symptoms was used assess prevalence self-perceived symptoms. The...
Objective. Amino acids (AA) and their derivatives play an integral role in the synthesis of structural regulatory elements human organisms therefore pathologies such as systemic sclerosis that may alter blood pattern these compounds. This study aimed to evaluate changes plasma concentrations amino acid-related metabolites scleroderma a search for potential biomarkers mechanisms disease. Methods. Plasma samples from 42 patients diagnosed with (SSc) according 2013 American College Rheumatology...
Chronic hemodialysis (HD) may lead to losses of carnitine from plasma and muscle. Plasma does not reflect the body content carnitine. The purpose this study was evaluation total free muscle concentrations (TPC, FPC, TMC, FMC), glycogen relationship between tissue basic indices lipid metabolism in HD patients. studies were conducted two groups: first one consisted 37 patients (19 F, 18 M), second served as control composed 29 (10 19 M) with healthy kidneys. Tissue specimens taken during...
Specific systemic autoimmune syndrome characterized by inflammatory myopathy, arthritis or arthralgias, interstitial lung disease (ILD), fever, Raynaud's phenomenon, and mechanic's hands is called antisynthetase (AS). The aim of this study was to assess the clinical spectrum associated with presence aminoacyl-transfer RNA synthetase autoantibodies (ASA).