A5100372263- Neuroscience and Neural Engineering
- Advanced Memory and Neural Computing
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Flame retardant materials and properties
- Optical Imaging and Spectroscopy Techniques
- Advanced Sensor and Energy Harvesting Materials
- Natural Fiber Reinforced Composites
- Global Cancer Incidence and Screening
- Supercapacitor Materials and Fabrication
- Tea Polyphenols and Effects
- Neuroinflammation and Neurodegeneration Mechanisms
- Ophthalmology and Visual Impairment Studies
- Nutrition and Health in Aging
- Muscle activation and electromyography studies
- Tuberculosis Research and Epidemiology
- Semiconductor materials and devices
- Colorectal Cancer Screening and Detection
- Tryptophan and brain disorders
- Electronic and Structural Properties of Oxides
- Corneal surgery and disorders
- Multiple and Secondary Primary Cancers
- Migraine and Headache Studies
- Neuroscience and Neuropharmacology Research
- Cancer Risks and Factors
Zhejiang Cancer Hospital
2023-2024
Northeast Agricultural University
2024
Chinese Academy of Sciences
2004-2023
Center for Excellence in Brain Science and Intelligence Technology
2023
Rice University
2020-2022
Jiamusi University
2021
Southern Medical University
2020
Guangdong Provincial People's Hospital
2020
Shantou University
2020
Shantou University Medical College
2020
Understanding brain functions at the circuit level requires time-resolved simultaneous measurement of a large number densely distributed neurons, which remains great challenge for current neural technologies. In particular, penetrating electrodes allow recording from individual neurons high temporal resolution, but often have larger dimensions than biological matrix, induces significant damage to tissues and therefore precludes implant density that is necessary mapping neuronal populations...
Objective. Implanted microelectrodes provide a unique means to directly interface with the nervous system but have been limited by lack of stable functionality. There is growing evidence suggesting that substantially reducing mechanical rigidity neural electrodes promotes tissue compatibility and improves their recording stability in both short- long-term. However, miniaturized dimensions ultraflexibility desired for mitigating responses preclude probe's self-supported penetration into brain...
Neurovascular coupling, the close spatial and temporal relationship between neural activity hemodynamics, is disrupted in pathological brain states. To understand altered neurovascular disorders, longitudinal, simultaneous mapping of hemodynamics critical yet challenging to achieve. Here, we use a multimodal platform mouse model stroke realize long-term, spatially resolved tracking intracortical cerebral blood flow same regions. We observe pronounced dissociation that occurs immediately...
Brain function can be best studied by simultaneous measurements and modulation of the multifaceted signaling at cellular scale. Extensive efforts have been made to develop multifunctional neural probes, typically involving highly specialized fabrication processes. Here, we report a novel probe platform realized applying ultrathin nanoelectronic coating (NEC) on surfaces conventional microscale devices such as optical fibers micropipettes. We fabricated NECs planar photolithography techniques...
Polyaniline nanowires (PANI NWs) were synthesized under different temperatures through a facile hydrothermal method and used as electrodes for high-performance pseudocapacitor. The resulting samples analyzed by X-ray diffraction, Fourier transform infrared spectroscopy, Raman scanning electron micrographs, thermogravimetric analysis, photoelectron spectroscopy. Electrochemical properties of these PANI are studied cyclic voltammetry, galvanostatic charge–discharge test, electrochemical...
SUMMARY Monitoring neural population activity at single-cell resolution is essential for driving fundamental research and clinical innovations. However, translating advanced recording techniques from animal models to humans remains a significant challenge. Flexible electrodes have recently emerged as powerful tools large-scale single-unit recordings due their superior biocompatibility high density. Here, we demonstrate reliable, high-density during intraoperative procedures in human patients...
As the global population ages, burden of cancer is increasing. We aimed to assess impact ageing on cancer-related disability-adjusted life years (DALYs).
Polypropylene (PP)/poly (lactic acid)(PLA) semibiocomposites were prepared by melt blending of PP with PLA and styrene-ethylene-butylene-styrene-g-maleic anhydride (SEBS-g-MAH) copolymer at the ratio 60/15/25, further modified intumescent flame retardants (IFR) containing two kinds phosphorus nitrogen compounds to meet fire protection requirements. The mechanical properties morphology characterized testing scanning electron microscopy (SEM). retardancy thermal degradation investigated...
Purpose: Tension-type headache (TTH), the most prevalent primary disorder, imposes an enormous burden on people of world. The quest to ease suffering from this neurological disorder has sustained research interest. present study aimed at evaluating amplitude low-frequency oscillations (LFOs) brain in multiple frequency bands patients with TTH. Methods: To address question, 63 participants were enrolled study, including 32 TTH and 31 healthy controls (HCs). For all participants, fluctuation...
Neural interfaces for stable access to the spinal cord (SC) electrical activity can benefit patients with motor dysfunctions. Invasive high-density electrodes directly extract signals from SC neuronal populations that be used facilitation, adjustment, and reconstruction of actions. However, developing neural achieve high channel counts long-term intraspinal recording remains technically challenging. Here, a biocompatible hyperflexible electrode array (SHEA) an ultrathin structure minimizes...
Abstract Introduction Breast cancer is a significant contributor to female mortality, exerting public health burden worldwide, especially in China, where risk‐prediction models with good discriminating accuracy for breast are still scarce. Methods A multicenter screening cohort study was conducted as part of the Cancer Screening Program Urban China. Dwellers aged 40–74 years were recruited between 2014 and 2019 prospectively followed up until June 30, 2021. The entire data set divided by...
Epiretinal prostheses have been reported to restore partial visual function of patients suffering from retinal degenerative diseases. The design stimulating electrode array the epiretinal prosthesis is one pivotal factors influence its performance and spatial resolution. Because cell density distribution ganglion cells(RGCs) anatomic structure varied with eccentricity, electrodes should be designed specifically at different eccentricities obtain optimal restoration performance. In this...
Frequent consumption of fried foods has been strongly associated with a higher risk anxiety and depression, particularly among young individuals.
Abstract Neurovascular coupling, the close spatial and temporal relationship between neural activity hemodynamics, is disrupted in pathological brain states. To understand altered neurovascular disorders, longitudinal, simultaneous mapping of hemodynamics critical yet challenging to achieve. Here, we employ a multimodal platform mouse model stroke realize long-term, spatially-resolved tracking intracortical cerebral blood flow same regions. We observe pronounced dissociation that occurs...
To investigate the correlative factors of vision regression after Implantable Collamer Lens (ICL) surgery from perspective binocular and to develop a predictive model for refractive change over long term. This was prospective study 30 subjects (60 implants), who underwent ICL at Guangdong General Hospital. Corrected distance visual acuity, uncorrected spherical equivalent (SE), axial length examination using virtual reality were analyzed before, 1 month year surgery. Mean SE (-12.01 ± 0.86)...
The synergistic flame retardancy of aluminium dipropylphosphinate (ADPP) and melamine (ME) in polyamide 6 (PA6) was studied by the limiting oxygen index (LOI) measurement, vertical burning test, cone calorimeter mechanism also discussed thermogravimetric residual analyses. experimental results indicated that there obvious between ADPP ME under their appropriate weight ratios. analysis residues obtained test showed ADPP/ME played role retardance gaseous- condensed-phase mechanisms, where, on...