A5002956911- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Photosynthetic Processes and Mechanisms
- Plant Stress Responses and Tolerance
- Medical Imaging Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Light effects on plants
- Radiomics and Machine Learning in Medical Imaging
- Plant nutrient uptake and metabolism
- Plant Reproductive Biology
- MicroRNA in disease regulation
- Cancer Research and Treatments
- Peptidase Inhibition and Analysis
- Radiopharmaceutical Chemistry and Applications
- Protease and Inhibitor Mechanisms
- Cancer-related molecular mechanisms research
- Plant biochemistry and biosynthesis
- CRISPR and Genetic Engineering
- Virus-based gene therapy research
- Plant-Microbe Interactions and Immunity
- Advanced Radiotherapy Techniques
- Ubiquitin and proteasome pathways
- Circular RNAs in diseases
- Cancer-related Molecular Pathways
Shanghai Jiao Tong University
2014-2025
Fujian Agriculture and Forestry University
2016-2025
Ruijin Hospital
2015-2025
Xiamen University
2025
Inner Mongolia Agricultural University
2024-2025
China United Network Communications Group (China)
2024
Shanxi Medical University
2023
Guilin Medical University
2023
Jiangxi University of Technology
2023
Agriculture and Forestry University
2023
MicroRNAs (miRNAs) play important roles in carcinogenesis. The global miRNA expression profile of gastric cancer has not been reported. purpose the present study was to determine cancer.Total RNA were first extracted from primary tissues and adjacent non-tumorous then small isolated RNAs (< 300 nt) 3'-extended with a poly(A) tail. Hybridization carried out on microParaflo microfluidic chip (LC Sciences, Houston, TX, USA). After hybridization detection by fluorescence labeling using...
Crosstalk between salicylic acid (SA) and jasmonic (JA) signaling is well-studied but not during leaf senescence. We found that the senescence-specific WRKY53 transcription factor interacts with JA-inducible protein EPITHIOSPECIFYING SENESCENCE REGULATOR (ESR/ESP). The expression of these genes antagonistically regulated in response to JA SA, respectively, each negatively influences other. Leaf senescence accelerated ESR knockout plants (ESR-KO) retarded overexpressors (ESR-OE), reverse true...
Summary WRKY transcription factors play a central role in controlling leaf senescence Arabidopsis. One important member, WRKY53, is tightly regulated by various mechanisms, and convergence node between pathogen responses. Using WRKY53 yeast two‐hybrid screen, we isolated the HECT domain E3 ubiquitin ligase UPL5. In contrast to mammals, Arabidopsis contains only seven ligases, whose targets functions are largely unknown. cells, UPL5 interacts with via its leucine zipper domain, this...
This article concerns the intriguing protein Whirly1 (Why1) that belongs to a small family of single-stranded DNA-binding proteins and has been described have functions in nucleus ([Desveaux et al., 2002][1]; [Yoo 2007][2]). In contrast, vitro import assays with isolated organelles
A link between the scent and color of Narcissus tazetta flowers can be anticipated due to their biochemical origin, as well similar biological role. Despite obvious aesthetic ecological significance these colorful fragrant components molecular profiles pigments, formation has addressed in some cases. However, regulatory mechanism correlation patterns is less clear. We simultaneously used one way address how floral different tissues are generated during development an individual plant by...
Abstract Objectives We aimed to investigate the role of [ 68 Ga]FAPI-04 and 18 F]FDG dual-tracer PET/CT for initial assessment gastric cancer explore factors associated with their uptake. Methods This study enrolled 62 patients histopathologically confirmed cancer. compared diagnostic performance Ga]FAPI-04, F]FDG, combined PET/CT. The standardized uptake value (SUV) tumor-to-background ratio (TBR) were also measured, that influence tracer analyzed. Results detected more primary lesions...
Abstract The color of flowers is one the main characteristics adopted for plants to attract pollinators ensure reproductive success plant, they are also important in their ornamental appeal Narcissus plant. In this study, we identified a NtMYB12 locus encoding an R2R3-MYB transcription factor. Comparative transcriptome analysis loss- and gain- tissue relative wild-type narcissus showed was mainly involved flavonol phenylpropanoid metabolic pathways. Biochemical evidences dual-luciferase...
NAC (NAM, ATAF1, 2 and CUC2) family is a plant-specific transcription factor it controls various plant developmental processes. In the current study, 124 members were identified in Zea mays phylogenetically clustered into 13 distinct subfamilies. The whole genome duplication (WGD), especially an additional WGD event, may lead to expanding ZmNAC members. Different subfamily has different expansion rate, preference was found during maize. Moreover, events might occur after divergence of...
Purpose: Elevated glucose uptake is a hallmark of cancer.Fluorodeoxyglucose (FDG) was believed to indicate the aggressiveness tumors and standardized value (SUV) well-known measurement for FDG in positron emission tomography-computed tomography (PET/CT).However, SUV variable due heterogeneity tumors.Methods: 126 patients with colorectal cancer underwent 18 F-FDG PET/CT scanning before surgery between Jan 2011 April 2016.Cancer-associated fibroblast (CAF) densities were calculated inForm...
Leaf senescence is controlled by a complex regulatory network in which robustness ensured the activity of transcription factors and epigenetic regulators. However, how these coordinate process leaf remains poorly understood. We found that WHIRLY1 interacts with Histone Deacetylase (HDA)15, Reduced Potassium Dependence3 (RPD3)/HDA1-type HDA, using green fluorescent protein-nanotrap-mass spectrum assays. The development-dependent interaction between HDA15 was further confirmed bimolecular...
The WRKY family of transcription factors (TFs) is one the ten largest families TFs in higher plants and has been implicated multiple biological processes. Here, we identified 121 moso bamboo, including five novel members that were not annotated Phyllostachys edulis genomic database. Estimation divergence time paralogous gene pairs revealed an important role recent whole-genome duplication expansion family. Expression analysis based on quantitative reverse-transcription polymerase chain...
Fas induces apoptosis in activated T cell to maintain immune homeostasis, but the effects of non-apoptotic signaling on cells remain unclear. Here we show that promotes TH9 differentiation by activating NF-κB via Ca2+-dependent PKC-β activation. In addition, also phosphorylates p38 inactivate NFAT1 and reduce NFAT1-NF-κB synergy promote Fas-induced transcription program. ligation exacerbates inflammatory bowel disease increasing differentiation, antitumor activity inhibitor-treated cells....