A5037302732- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Plant Gene Expression Analysis
- Plant Pathogenic Bacteria Studies
- Plant Pathogens and Fungal Diseases
- Nematode management and characterization studies
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Postharvest Quality and Shelf Life Management
- Legume Nitrogen Fixing Symbiosis
- Plant Disease Resistance and Genetics
- Biofuel production and bioconversion
- Plant biochemistry and biosynthesis
- Polysaccharides and Plant Cell Walls
- Advanced biosensing and bioanalysis techniques
- Seed Germination and Physiology
- Pancreatic function and diabetes
- Insect-Plant Interactions and Control
- Plant responses to water stress
- Mitochondrial Function and Pathology
- Cancer, Hypoxia, and Metabolism
- Plant Micronutrient Interactions and Effects
- Transgenic Plants and Applications
Northeast Agricultural University
2015-2025
Ministry of Agriculture and Rural Affairs
2021-2025
Zhejiang University
2023-2025
South China University of Technology
2025
East China University of Science and Technology
2015-2024
Sichuan University
2021-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Sun Yat-sen University
2024
Sinopec Research Institute of Petroleum Processing
2023
Sinopec (China)
2022-2023
Autophagy and glycolysis are highly conserved biological processes involved in both physiological pathological cellular programs, but the interplay between these is poorly understood. Here, we show that glycolytic enzyme lactate dehydrogenase A (LDHA) activated upon UNC-51-like kinase 1 (ULK1) activation under nutrient deprivation. Specifically, ULK1 directly interacts with LDHA, phosphorylates serine-196 when nutrients scarce promotes production. Lactate connects autophagy through Vps34...
Plant heat stress transcription factors (Hsfs) are the critical components involved in mediating responses to various environmental stressors. However, detailed roles of many plant Hsfs far from fully understood. In this study, an Hsf (SlHsfA3) was isolated cultivated tomato (Solanum lycopersicum, Sl) and functionally characterized at genetic developmental levels. The nucleus-localized SlHsfA3 basally ubiquitously expressed different organs. expression induced dramatically by stress,...
Solanum lycopersicum and habrochaites are closely related plant species; however, their cold tolerance capacities different. The wild species S. is more tolerant than the cultivated lycopersicum.The transcriptomes of leaf tissues under stress were studied using Illumina high-throughput RNA sequencing. results showed that 200 million reads could be mapped to identify genes, microRNAs (miRNAs), alternative splicing (AS) events confirm transcript abundance stress. indicated 21% 23% genes...
Autophagy-based protein degradation is emerging as a promising technology for anti-diseases and innovative drug discovery. Here, we demonstrate novel type of autophagy-targeting chimera (AUTAC) to degrade by targeting autophagy key LC3. The best compound 10f powerfully degraded BRD4 through the pathway exhibited good anti-proliferative activity in multiple tumor cells, providing powerful toolbox medicinal chemists study disease-related targets with autophagy-based degradation.
It is highly desirable and of utmost importance to find eco-friendly green approaches for a sustainable environment. Nowadays researchers from different communities have determined that it economical demanding synthesize nanomaterials by utilizing plants, fruits, yeast, algae, fungi, other techniques as stabilizers mediators. Compared the chemical synthesis techniques, plant-mediated approach considered an eco-friendly, efficient, easy, stable, cost-effective means nanomaterials. Among...
Abstract Solanum habrochaites (SH), a wild species closely related to ‘Ailsa Craig’ (AC), is an important germplasm resource for modern tomato breeding. Trichomes, developed from epidermal cells, have role in defense against insect attack, and their secretions are of non-negligible value. Here, we found that the glandular heads type VI trichomes were clearly distinguishable between AC SH under cryo-scanning electron microscopy, difference indicating could secrete more anti-insect metabolites...
Summary Plasma membrane intrinsic proteins (PIPs) are known to be major facilitators of the movement a number substrates across cell membranes. From drought‐resistant cultivar Oryza sativa (rice), we isolated an OsPIP1;3 gene single‐nucleotide polymorphism (SNP) that is mostly expressed in rice roots and strongly responsive drought stress. Immunocytochemistry showed majorly accumulated on proximal end endodermis surface around xylem. Expression GFP‐OsPIP1;3 alone Xenopus oocytes or...
Botrytis cinerea infection can be very devastating for tomato production, as it result in a large-scale reduction fruit production and quality after harvest. Thus, negatively affects yield quality. In this study, biocontrol bacteria CQ-4 was isolated screened from the rhizosphere soil of plants. Morphological, physiological, biochemical characteristics 16S rDNA sequence analysis revealed that belongs to species Pseudomonas aeruginosa, which has strong antagonistic effect against cinerea....
Tyrosinase (EC 1.14.18.1) plays an indispensable role in the rate-limiting steps of melanin biosynthesis, and its uncontrolled activity may result various diseases, such as albinism, melanoma, freckles, etc. The inhibition tyrosinase provide a useful efficient strategy to treat hyperpigmentation disorders. However, widely used inhibitors, like α-arbutin, hydroquinone, kojic acid, have many shortcomings, lower efficacy much more side effects. Herein, we reported use homology modeling...
Tomato gray mold disease caused by Botrytis cinerea is a serious that threatens tomato production around the world. Clonostachys rosea has been used successfully as biocontrol agent against divergent plant pathogens, including B. cinerea. To understand signal transduction pathway of C. rosea-induced resistance to disease, effects on leaves along with changes in activities three defense enzymes (phenylalanine ammonialyase [PAL], polyphenol oxidase [PPO], and catalase [CAT]), second messengers...