A5029197324- COVID-19 and healthcare impacts
- COVID-19 epidemiological studies
- Infection Control and Ventilation
- Antimicrobial Resistance in Staphylococcus
- Viral Infections and Outbreaks Research
- Bacterial Identification and Susceptibility Testing
- COVID-19 Pandemic Impacts
- Fungal Infections and Studies
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Antibiotic Use and Resistance
- Antifungal resistance and susceptibility
- Venous Thromboembolism Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- Hospital Admissions and Outcomes
- Acute Ischemic Stroke Management
- Geriatric Care and Nursing Homes
- Healthcare Operations and Scheduling Optimization
- Health Policy Implementation Science
- Disaster Response and Management
- Disaster Management and Resilience
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Plant Pathogens and Fungal Diseases
- Climate Change and Health Impacts
Singapore General Hospital
2015-2025
SingHealth
2021
BackgroundThe emerging fungal pathogen Candida auris poses a serious threat to global public health due its worldwide distribution, multidrug resistance, high transmissibility, propensity cause outbreaks, and mortality. We aimed characterise three unusual C isolates detected in Singapore, determine whether they constitute novel clade distinct from all previously known clades (I–V).MethodsIn this genotypic phenotypic study, we characterised clinical isolates, which were cultured...
In the current COVID-19 pandemic, aggressive Infection Prevention and Control (IPC) measures have been adopted to prevent health care-associated transmission of COVID-19. We evaluated impact a multimodal IPC strategy originally designed for containment on rates other hospital-acquired-infections (HAIs).
Carbapenem resistant Enterobacteriaceae (CRE) is increasingly reported worldwide. A similar increase seen in Singapore since identification of its first case 2008. The aim this study was to identify local risk factors for carriage CRE patients from an acute tertiary care hospital Singapore.A matched case-control conducted on inpatients treated January 1, 2011 till December 31, 2013. Two hundred and three cases infection or colonization were with 203 controls. types identified by PCR....
Summary Background The emerging fungal pathogen Candida auris poses a serious threat to global public health due its worldwide distribution, multidrug-resistance, high transmissibility, propensity cause outbreaks and mortality rates. We report three C. isolates detected in Singapore, which are genetically distinct from all known clades (I-V) represent new clade (Clade VI). Methods Three epidemiologically unlinked clinical belonging the potential were whole-genome sequenced phenotypically...
In response to global concerns about the largest Ebola virus disease (EVD), outbreak to-date in West Africa documented healthcare associated transmission and risk of spread, International Society Chemotherapy (ISC) Infection Control Working Group created an Readiness Checklist assess preparedness institutions around globe. We report data from electronic checklist that was disseminated medical professionals October December 2014 identify action needed towards better levels. Data 192 (one...
With astonishing speed, COVID-19 has become a global pandemic. As it is uncertain when the pandemic will be controlled, crucial for procedurists of all stripes to familiar and confident in performing procedures patients prevent intra-hospital infection. In this article, we detail our approach on how perform interventional at bedside isolation room with patient transferred radiology centre. These workflows have been developed conjunction multiple other stakeholders within hospital, drawing...
Large-scale quarantine facilities staffed with non-healthcare workers (NHCW) were instrumental in preventing community spread of COVID-19 (coronavirus disease 2019). The objective this study was to determine the effectiveness a newly developed procedural skills training framework ensuring personal protective equipment (PPE) compliance PPE-naïve NHCWs.We PPE for NHCWs using Learn, See, Practice, Prove, Do, and Maintain (LSPPDM) international guidelines on healthcare workers. underwent...
Abstract Sporadic clusters of healthcare-associated coronavirus disease 2019 (COVID-19) occurred despite intense rostered routine surveillance and a highly vaccinated healthcare worker (HCW) population, during community surge the severe acute respiratory virus 2 (SARS-CoV-2) B.1.617.2 δ (delta) variant. Genomic analysis facilitated timely cluster detection uncovered additional linkages via HCWs moving between clinical areas among sharing common lunch area, enabling early intervention.
Abstract Objective: To describe OXA-48–like carbapenem-producing Enterobacteriaceae (CPE) outbreaks at Singapore General Hospital between 2018 and 2020 to determine the risk associated with OXA-48 carriage in outbreak. Design: Outbreak report case–control study. Setting: (SGH) is a tertiary-care academic medical center 1,750 beds. Methods: Active surveillance for CPE conducted selected high-risk patient cohorts through molecular testing on rectal swabs or stool samples. Patients are isolated...
<ns4:p><ns4:bold>Background:</ns4:bold>The Singapore COVID-19 multi-ministry taskforce commissioned community care facilities (CCFs) as a hospital-sparing strategy amidst rising coronavirus disease 2019 (COVID-19) cases. An exhibition centre was repurposed within ten days an ad-hoc 3200-bed medical facility (CCF@EXPO) to isolate and treat infected patients concerns of potential transmissions healthcare staff. This paper deconstructs the implementation CCF@EXPO infection prevention control...
Background: Healthcare-associated central line associated bloodstream infection (HA-CLABSI) surveillance is important for monitoring healthcare-associated infections (HAIs) and evaluating effectiveness of prevention (IP) measures. However, implementing it a laborious time-consuming approach. Exclusive focus on lines neglects HAI risk due to peripheral vascular catheters. This study aimed assess whether HA-CLABSI incidence could be inferred from HA-bloodstream (BSI) trends explore shift...
Background: In the last 2 years of COVID-19 pandemic, Singapore has been forced to explore alternative sites quarantine persons or manage infected cases during surge periods in a national effort not overwhelm public healthcare facilities. External facilities were created at EXPO and further extended D’Resort other hotels May 2020. Infection prevention (IP) practices implemented these external facilities, where training non–healthcare staff quickly learn understand required challenging. A...
Background: Singapore General Hospital (SGH) is the largest acute tertiary-care hospital in Singapore. Healthcare workers (HCWs) are at risk of acquiring COVID-19 both community and workplaces. SGH has a robust exposure management process including prompt contact tracing, immediate ring fencing, lock down affected cubicles or single room isolation for patient contacts, home orders staff contacts cases during containment phase pandemic. Contacts were also placed on enhanced surveillance with...
Background: The ongoing COVID-19 pandemic tests the healthcare system in many ways. scarcity of resources poses challenges to infection prevention (IP) practices. We describe our experience managing such care patients hospital as well community settings. Methods: plan traditionally included only plans for delivery management within hospital. However, on March 25, 2020, a decision was made by Ministry Health set up swab isolation (SIFs) and facilities (CCFs) meet growing demand beds migrant...
Abstract Background The International Nosocomial Infection Control Consortium surveillance reported Central line-associated bloodstream infection (CLABSI) rate of 4.1 per 1000 central-line days in 703 ICUs 50 countries. Methods At the Singapore General Hospital (SGH) a 1,700-bed tertiary care hospital, we conducted retrospective matched case control study over 3-year period from 2018 to 2020, identify risk-factors associated with development healthcare CLABSI adult inpatients. Cases and...