Simone Reges Perales

ORCID: 0000-0003-2263-9254
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About
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease and Transplantation
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease Diagnosis and Treatment
  • COVID-19 Impact on Reproduction
  • Renal Transplantation Outcomes and Treatments
  • Genetic and Kidney Cyst Diseases
  • Drug-Induced Hepatotoxicity and Protection
  • Pancreatic and Hepatic Oncology Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Sarcoma Diagnosis and Treatment
  • Organ Donation and Transplantation
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Congenital Anomalies and Fetal Surgery
  • Vascular Malformations and Hemangiomas
  • Viral-associated cancers and disorders
  • Pancreatitis Pathology and Treatment
  • Parvovirus B19 Infection Studies
  • Blood donation and transfusion practices
  • Cancer, Lipids, and Metabolism
  • Folate and B Vitamins Research
  • Radiomics and Machine Learning in Medical Imaging
  • Gallbladder and Bile Duct Disorders
  • SARS-CoV-2 and COVID-19 Research

Universidade Estadual de Campinas (UNICAMP)
2015-2024

Hospital de Clínicas da Unicamp
2016-2023

Centro Universitário da Cidade
2022

Weatherford College
2022

Universidade Federal do Triângulo Mineiro
2019

Rutgers, The State University of New Jersey
2018

Purpose This paper aims to address problems in patient flow and identify the reasons behind extensive wait time at a public liver transplant outpatient clinic an education research hospital through use of Lean health-care theories. Design/methodology/approach opted for application thinking action strategy. Data were collected personal observations, interviews with users team brainstorming. A value stream map was developed, improvement possibilities identified non-value-added activities...

10.1108/lhs-03-2018-0016 article EN Leadership in health services 2018-06-08

to characterize the profile of potential and effective organ donors, identify factors related non-donation.the data was collected from Organization Organ Donation forms during period January 2013 April 2018. The statistical analysis done by Biostatistic Service School Medical Sciences UNICAMP.the study analyzed 1,772 donors; male gender predominant (57.39%). Vascular injuries (n=996) were main cause brain death. family refusal (42.8%) leading non-donation organs. There difference between...

10.1590/0100-6991e-201922180 article PT cc-by Revista do Colégio Brasileiro de Cirurgiões 2019-01-01

Recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) has a poor prognosis, and the adjusted effect different treatments on post-recurrence survival (PRS) not been well defined. This study aims to evaluate prognostic predictive variables associated with PRS.This Latin American multicenter retrospective cohort included HCC patients who underwent LT between years 2005-2018. We evaluated baseline characteristics at time recurrence diagnosis PRS (Cox regression analysis)....

10.1111/liv.14736 article EN Liver International 2020-11-21

To investigate whether quantitative computed tomography (CT) measurements can predict microvascular invasion (MVI) in hepatocellular carcinoma (HCC).This was a retrospective analysis of 200 cases surgically proven HCCs 125 consecutive patients evaluated between March 2010 and November 2017. We quantitatively measured regions interest lesions adjacent areas the liver on unenhanced CT scans, as well arterial, portal venous, equilibrium phases contrast-enhanced scans. Enhancement profiles were...

10.1590/0100-3984.2018.0123 article PT Radiologia Brasileira 2019-08-16

Background: Cholelithiasis is a highly prevalent condition, and choledocholitiasis high morbidity complication requires accurate methods for its diagnosis. Aim: To evaluate the population of patients with suspected check statistical value magnetic resonance cholangiopancreatography, ultrasonography, laboratory clinic these comparing them to results obtained by perioperative cholangiography. Methods: This retrospective cohort study, which were evaluated 76 cholelithiasis choledocholithiasis....

10.1590/0102-672020180001e1416 article EN cc-by ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2019-01-01

Rationale: Lysosomal acid lipase deficiency (LAL-D) is a poorly diagnosed genetic disorder characterized by the accumulation of cholesteryl esters and triglycerides in many tissues, leading to dyslipidemia cardiovascular complications. In liver, deposits are found within hepatocytes Kupffer cells, generating microvesicular steatosis, progressive fibrosis, cirrhosis. Sebelipase alfa target therapy which can improve laboratory changes reduce progression liver damage, but this not yet widely...

10.1097/md.0000000000030315 article EN cc-by-nc Medicine 2022-09-02

Giant hepatic hemangiomas are occasional in patients with cirrhosis.It remains a challenge to decide on the need for treatment and choose most appropriate intervention.A 62-year-old woman was recently diagnosed cirrhosis complained of upper abdominal fullness, reduction oral food intake, weight loss 6 kg over last three years.Upper digestive endoscopy evidenced thin-caliber esophageal varices significant extrinsic compression lesser gastric curvature.Abdominal computed tomography revealed an...

10.4322/acr.2024.485 article EN cc-by Autopsy and Case Reports 2024-01-01

Abstract Background & aim Liver transplantation (LT) selection models for hepatocellular carcinoma (HCC) have not been proposed to predict waitlist dropout because of tumour progression. The this study was compare the alpha‐foetoprotein (AFP) model and other pre‐LT in their prediction HCC dropout. Methods A multicentre cohort conducted 20 Latin American transplant centres, including 994 listed patients LT with from 2012 2018. Longitudinal characteristics, patterns progression were...

10.1111/liv.15223 article EN Liver International 2022-03-19

ABSTRACT Objective: to correlate clinical and epidemiological data with the pathological analysis of liver explants from patients undergoing transplantation for hetapocarcinoma in UNICAMP HC verify whether MELD MELD-Na scores are reliable factors predict a worse post-transplant prognosis. Methods: we studied transplants carried out between May 2010 November 2017. After excluding 38 patients, included 87, analyzing laboratory correlation outcome Microvascular Invasion (MVI). Subsequently,...

10.1590/0100-6991e-20212997 article EN cc-by Revista do Colégio Brasileiro de Cirurgiões 2021-01-01
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