Márcia Halpern

ORCID: 0000-0002-3000-3881
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About
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Research Areas
  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Antibiotics Pharmacokinetics and Efficacy
  • Mycobacterium research and diagnosis
  • COVID-19 Clinical Research Studies
  • Liver Disease and Transplantation
  • Antibiotic Resistance in Bacteria
  • Organ Transplantation Techniques and Outcomes
  • COVID-19 Impact on Reproduction
  • Long-Term Effects of COVID-19
  • Tuberculosis Research and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Organ Donation and Transplantation
  • Antimicrobial Resistance in Staphylococcus
  • Poxvirus research and outbreaks
  • Nail Diseases and Treatments
  • Bacillus and Francisella bacterial research
  • Renal Transplantation Outcomes and Treatments
  • Cytomegalovirus and herpesvirus research
  • Facial Nerve Paralysis Treatment and Research
  • Hematological disorders and diagnostics
  • Pregnancy and Medication Impact
  • Health and Medical Studies
  • Healthcare Regulation

Universidade Federal do Rio de Janeiro
2008-2024

Hospital Universitário Clementino Fraga Filho
2005-2024

D’Or Institute for Research and Education
2021-2024

Hospital Geral de Bonsucesso
2006-2021

Newark Beth Israel Medical Center
1948

Abstract Background Patients colonized with carbapenem-resistant Enterobacteriaceae (CRE) are at higher risk of developing CRE infection after liver transplantation (LT), associated high morbidity and mortality. Prediction model for LT among carriers could be useful to target preventive strategies. Methods Multinational multicenter cohort study consecutive adult patients underwent before or LT, from January 2010 December 2017. Risk factors were analyzed by univariate analysis Fine-Gray...

10.1093/cid/ciab109 article EN Clinical Infectious Diseases 2021-02-05

Abstract Background Infection with carbapenem-resistant Acinetobacter baumannii has been associated high morbidity and mortality in solid organ transplant recipients. The main objective of this study was to assess the influence carbapenem resistance other potential risk factors on outcome A. infection after kidney liver transplantation. Methods Retrospective a case series among renal primary death infection. Multivariate logistic regression used covariates outcome. Results Forty-nine cases...

10.1186/1471-2334-12-351 article EN cc-by BMC Infectious Diseases 2012-12-01

Invasive fungal disease (IFD) is an important complication after solid organ transplantation (SOT). A marked geographic variation in the epidemiology of IFD kidney (KT) has been suggested by results previous studies. Nevertheless, data from Latin American centers are scarce.This study sought to describe at a Brazilian KT center.This was retrospective single-center cohort that included patients who underwent between 1998 and 2009 were followed up until July 2015. Cases simultaneous...

10.1016/j.transproceed.2016.06.019 article EN publisher-specific-oa Transplantation Proceedings 2016-09-01

This retrospective cohort study assessed the results of implementation preventive recommendations for tuberculosis (TB) among renal transplant recipients in an endemic area (Rio de Janeiro, Brazil). Subjects were defined as at high risk TB if they had latent infection (LTBI), reported recent close contact with individuals or received a graft from donor LTBI. A 6-month course isoniazid therapy (IPT) was targeted to high-risk subjects. The end point confirmed by culture. Altogether, 535...

10.1111/ajt.12470 article EN cc-by-nc-nd American Journal of Transplantation 2013-10-02

Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of infection after orthotopic liver transplantation (OLT). Colonization with MRSA associated higher risk infection. Previous studies have shown high prevalence colonization among OLT candidates. However, the still unclear. The objective this study was to estimate incidence and factors OLT. This prospective cohort including patients submitted between years 2000 2002. Surveillance cultures nasal swab specimens were...

10.1002/lt.20338 article EN Liver Transplantation 2005-01-21

Tuberculosis (TB) has a high prevalence in Brazil. The scenario of liver transplantation (LT) creates challenges: atypical presentation, treatment hepatotoxicity, and increased mortality. majority TB cases after represent reactivation latent infections; therefore, prophylaxis (PX) plays major role. aim this study was to evaluate the benefits PX LT based on pretransplantation tuberculin test (TT) an endemic area.Retrospective analysis medical data from 376 adult cirrhotic patients undergoing...

10.1016/j.transproceed.2010.12.033 article EN publisher-specific-oa Transplantation Proceedings 2011-01-01

Mpox is a zoonotic disease historically reported in Africa. Since 2003, limited outbreaks have occurred outside In 2022, the global spread of cases with sustained interhuman transmission and unusual features raised public health concerns. We explore mpox outbreak Rio de Janeiro (RJ) state, Brazil, an observational study mpox-suspected from June to December 2022. Data collection relied on healthcare notification form. Diagnosis was determined by MPXV-PCR. 46 confirmed cases, anti-OPXV IgG...

10.1002/jmv.29621 article EN Journal of Medical Virology 2024-04-24

The selection of donors for living donor liver transplantation (LDLT) is one the most important features in this kind surgery. aim study to describe our initial experience evaluation process. From December 2001 January 2005, 104 were evaluated 70 recipients (65 potential 39 adult recipients, and 31 pediatric recipients). Only 30 able donate: 13 group, 17 one. In general, utilization rate was 28.8% (30/104). For patients, 65 seen perform LDLT, which represents a 20%. 43.6%. exclusion criteria...

10.1111/j.1399-3046.2005.00465.x article EN Pediatric Transplantation 2006-03-27

Abstract Background Management of infections due to carbapenemase‐resistant Enterobacterales (CRE) in solid organ transplant (SOT) recipients remains a difficult challenge. The INCREMENT‐SOT‐CPE score has been specifically developed from SOT stratify mortality risk, but an external validation is lacking. Methods Multicenter retrospective cohort study liver (LT) colonized with CRE infection who after over 7‐year period. Primary endpoint was all‐cause 30‐day onset. A comparison between and...

10.1111/tid.14036 article EN cc-by-nc-nd Transplant Infectious Disease 2023-03-07

Abstract: The shortage of organ donors for low‐weight liver transplant recipients, especially small children, has led to the development new surgical techniques increase donor pool. Almost all these use left lateral segment (Couinaud's segments II and III), but even this graft could be too large children under 10 kg. We report here case an 8‐month‐old boy, weighing 6.1 kg, who received a monosegmental (segment III) from his grandmother 68 was reduced at surgery, before clamping vessels....

10.1046/j.1399-3046.2003.00140.x article EN Pediatric Transplantation 2004-03-26

AIDS is spreading rapidly in Brazil. Caused by the dimorphic fungus Paracoccidioides brasiliensis paracoccidioidomycosis (PBM) one of systemic mycoses most frequently diagnosed among immunocompetent individuals Latin America. The condition commonly agricultural workers living humid tropical and subtropical rural regions. According to Marques et al. estimated incidence PBM Brazilian patients 1992 was 0.09% 26 reported cases there a 29.4% mortality rate. Given current increase heterosexual...

10.1016/s1201-9712(98)90122-9 article EN cc-by-nc-nd International Journal of Infectious Diseases 1998-01-01
Carmen Infante-Domínguez Sonsoles Salto‐Alejandre Rocío Álvarez‐Marín Núria Sabé António Ramos and 95 more Asunción Moreno Kamilla Ferreira de Moraes Zaira R. Palacios‐Baena Patricia Muñoz Mario Fernández‐Ruiz Marino Blanes Carmen Fariñas Elisa Vidal Esperanza Merino Márcia Halpern Román Hernández‐Gallego Matteo Bassetti Alessandra Mularoni Álex Gutiérrez-Dalmau Matteo Rinaldi Silvia Jiménez‐Jorge Marta Bodro Luis Fernando Aranha-Camargo Maricela Valerio Javier Sánchez‐Céspedes Belén Gutiérrez‐Gutiérrez Maddalena Giannella Jesús Rodríguez‐Baño Jerónimo Pachón Elisa Cordero Carmen Infante-Domínguez Sonsoles Salto‐Alejandre Rocío Álvarez‐Marín Silvia Jiménez‐Jorge Javier Sánchez‐Céspedes Jerónimo Pachón Elisa Cordero José Miguel Cisneros Manuela Aguilar-Guisado J.M. Álamo-Martínez C. Bernal Bellido G. Bernal-Blanco Pedro Camacho Marta Puerta Carretero Carmen Cepeda Franco Miguel Ángel Gómez Bravo Antonio Grande‐Trillo Luis Miguel Marín Gómez Laura Merino Gema Montilla-Cosano María Paniagua‐García José Manuel Sobrino‐Márquez Diego Rangel‐Sousa Blanca Villacorta-Linaza Núria Sabé José González‐Costello Laura Lladó Edoardo Melilli António Ramos Jorge Calderón‐Parra Ana Arias Asunción Moreno Marta Bodro Laura Linares Sabina Herrera María Ángeles Marcos Frederic Cofán M. Castel Jordi Colmenero Kamilla Ferreira de Moraes Luís Fernando Aranha Camargo Zaira R. Palacios‐Baena Belén Gutiérrez‐Gutiérrez Jesús Rodríguez‐Baño Belén Gallego Natalia Maldonado-Lizarazo Patricia Muñoz Maricela Valerio Ainhoa Fernández‐Yunquera Carlos Ortiz‐Bautista María Luisa Rodríguez-Ferrero Mario Fernández‐Ruiz José María Aguado Francisco López‐Medrano Rafael San Juan Marino Blanes-Julia Rosa Blanes-Hernández Carmen Fariñas Francisco Arnaiz de las Revillas-Almajano Ignacio Fortea Ormaechea Claudia Gonzalez‐Rico Mónica Gozalo-Margüello Aritz Gil Ongay Milagros Heras Vicario Elisa Vidal Julián Torre-Giménez Julián Torre-Cisneros Esperanza Merino Pilar González-de-la-Aleja Silvia Otero-Rodríguez

Clinical phenotypes of COVID-19, associated with mortality risk, have been identified in the general population. The present study assesses their applicability solid organ transplant recipients (SOTR) hospital-admitted by COVID-19. In a cohort 488 SOTR, nonvaccinated (n = 394) and vaccinated 94) against SARS-CoV-2, we evaluated 16 demographic, clinical, analytical, radiological variables to identify clinical A, B, C. median age was 61.0 (51–69) years, 330 (67.6%) 158 (32.4%) were men women,...

10.1038/s41598-024-81099-2 article EN cc-by-nc-nd Scientific Reports 2024-12-03

Mpox is a zoonotic disease historically reported in Africa. Since 2003, limited outbreaks have occurred outside In 2022, the global spread of cases with sustained interhuman transmission and unusual features raised public health concerns. We explore mpox outbreak Rio de Janeiro (RJ) state, Brazil, an observational study mpox-suspected from June to December 2022. Data collection relied on healthcare notification form. Diagnosis was determined by MPXV-PCR. 46 confirmed cases, anti-VACV IgG...

10.22541/au.171221154.49449276/v1 preprint EN Authorea (Authorea) 2024-04-04

Os autores relatam um caso de paniculite criptocócica em paciente transplantado renal inicialmente tratado como celulite bacteriana. O diagnóstico definitivo só foi possível pela impressão clínica dermatológica confirmada pelo exame micológico. tratamento realizado a princípio com anfotericina B e posteriormente fluconazol, considerando-se as interações das drogas imunossupressoras utilizadas para evitar rejeição. A regressão alcançada no sexto mês tratamento, que, entanto, mantido por 12...

10.1590/s0365-05962008000300007 article PT cc-by-nc Anais Brasileiros de Dermatologia 2008-06-01
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