A5100661334- Protein Hydrolysis and Bioactive Peptides
- Obstructive Sleep Apnea Research
- Stock Market Forecasting Methods
- Nutritional Studies and Diet
- Sleep and related disorders
- Advanced Glycation End Products research
- Alcohol Consumption and Health Effects
- Adipose Tissue and Metabolism
- Mitochondrial Function and Pathology
- Genomics, phytochemicals, and oxidative stress
- Exercise and Physiological Responses
- Polysaccharides and Plant Cell Walls
- Phytochemistry and Biological Activities
- Financial Markets and Investment Strategies
- Educational Games and Gamification
- Pregnancy and preeclampsia studies
- Liver Disease Diagnosis and Treatment
- Muscle metabolism and nutrition
- Chronic Kidney Disease and Diabetes
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Plant Pathogenic Bacteria Studies
- Birth, Development, and Health
- Plant-Microbe Interactions and Immunity
- ATP Synthase and ATPases Research
University of California, Riverside
2023-2025
Taipei Medical University
2024
National Chung Hsing University
2008-2024
Kaohsiung Medical University
2024
Jen-Ai Hospital
2024
Chang Gung Memorial Hospital
2024
National Cheng Kung University
2007-2023
Cheng Hsin General Hospital
2012-2022
Central Taiwan University of Science and Technology
2006-2022
University of Taipei
2022
Osteosarcoma is the most common primary malignant bone tumor in children and adolescents has also been associated with a high degree of malignancy enhanced metastatic capacity. Curcumin (CUR) well known for its anti-osteosarcoma activity. However, both demethoxycurcumin (DMC), bisdemethoxycurcumin (BDMC) are natural curcumin analogues/congeners from turmeric whose role osteosarcoma development remains unknown.To evaluate growth inhibitory effects CUR, DMC BDMC on (HOS U2OS), breast...
Abstract In the past decade, high morbidity and mortality of atherosclerotic disease have been prevalent worldwide. High-fat food consumption has suggested to be an overarching factor for atherosclerosis incidence. This study aims investigate effects kefir peptides on high-fat diet (HFD)-induced in apolipoprotein E knockout ( ApoE −/− ) mice. 7-week old male normal C57BL/6 mice were randomly divided into five groups (n = 8). Atherosclerotic lesion development was established after fed HFD 12...
The increased prevalence of renal dysfunction and chronic kidney disease (CKD) the high costs poor outcomes treatment are a significant health issue. consequence blood pressure is target organ end-stage disease, which has been proven to be strong independent risk factor for adverse cardiovascular disease. A previous study showed that kefir products have anti-inflammatory anti-hypertensive activities immunological modulation functions. However, no data regarding beneficial effects peptides...
Liver fibrosis is a chronic liver disease caused by prolonged injuries. Excessive accumulation of extracellular matrix replaces the damaged hepatocytes, leading to fibrous scar formation and induction. Lactoferrin (LF) glycoprotein with conserved, monomeric signal polypeptide chain, exhibiting diverse physiological functions, including antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, antitumoral activities. Previous study has shown LF's protective role against...
Mitochondrial DNA (mtDNA) encodes essential protein subunits in the oxidative phosphorylation system and a set of tRNAs rRNAs, making it critical for mitochondrial cellular functions. Defects mtDNA are implicated range disorders diseases, including cancer neurodegeneration. In addition, plays role innate immune response inflammation, as is released into cytoplasm bloodstream. particularly susceptible to damage by endogenous exogenous factors, its stability maintained through redundancy,...
This cross-sectional survey study examined exercise, sleep quality, and quality of life (QOL) in 1230 Taiwanese university students. Compared with women, men had higher body mass index (BMI) (22.3 ± 4.1 vs 20.7 3.5 kg/m(2)), exercise frequency (2.6 1.7 2.0 1.4 d/wk), better (global Pittsburgh Sleep Quality Index 6.0 2.8 6.5 2.7), physical QOL (physical component summary 52.7 6.2 51.7 6.6), reporting good self-perceived health (62.2% 43.3%) (P <01). However, gender differences were...
To determine an appropriate trading time for buying or selling stocks is always a difficult task. The common way to deal with it using strategies formed by technical fundamental indicators. Lots of approaches have been presented on how form and set suitable parameters those strategies. Furthermore, some were also designed optimize strategy portfolio, which where the return risk portfolio can be maximized minimized, respectively. provide more useful we first define group (GTSP). Then,...
Mitochondrial DNA (mtDNA) modifications play an emerging role in innate immunity and inflammatory diseases. Nonetheless, relatively little is known regarding the locations of mtDNA modifications. Such information critically important for deciphering their roles instability, mtDNA-mediated immune responses, mitochondrial disorders. The affinity probe-based enrichment lesion-containing represents a key strategy sequencing Existing methods are limited specificity abasic (AP) sites, prevalent...
A novel kefir exopolysaccharides (KEPS) derived from grain fermentation were found to have a small molecular weight (12 kDa) compared the traditionally high (12,000 of kefiran (KE). KE has been shown possess antioxidant, blood pressure-lowering, and immune-modulating effects. In this study, we characterized KEPS evaluated their anti-inflammatory properties in vitro using RAW264.7 macrophages. The main monosaccharide components identified as glucose (98.1 ± 0.06%) galactose (45.36 0.16%)...
The anti-oral cancer effects of santamarine (SAMA), a
Previous studies have revealed the anti-inflammatory and neuroprotective properties of Hericium erinaceus extracts, including fact that active ingredient erinacine C (EC) can induce synthesis nerve growth factor. However, there is limited research on use mechanisms action EC in treating neuroinflammation. Hence, this study, inflammatory responses human BV2 microglial cells induced by LPS were used to establish a model assess anti-neuroinflammatory efficacy clarify its possible action. The...
The interaction among obstructive sleep apnea syndrome (OSAS) severity, sex, and obesity on cardiovascular risk as determined by serum levels of C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) remains unclear. Therefore, this study aimed to analyze individual associations between these three OSAS characteristics biomarkers determine whether the relationship was affected other features in patients with suspected OSAS. For all participants (n = 100), severity...
1. The effects of endurance training on the anti-oxidant status in diabetes were studied using obese Zucker rats. 2. We used a moderate exercise programme consisting treadmill running at 20 m/min and 0% incline for 1 h/day, 7 days/week, 8 weeks. At end experimental period, changes hepatic enzymes terms protein content mRNA levels detected western blotting analysis northern analysis, respectively. In addition, enzyme activity was determined. A significant reduction Mn-superoxide dismutase...
This paper proposes a neural fuzzy evaluation system (NFES) with significant variables selected from stepwise regression to predict apnea-hypopnea index (AHI) for evaluating obstructive sleep apnea (OSA). The considered are the change statuses of blood pressure (BP) before going and early in morning as well other five easily available measurements (age, body mass (BMI), etc.) so that users can use self-evaluation OSA. A total 150 subjects reviewed retrospectively categorized training (120...
• Reliability study of Deep ultra-violate (DUV) photodetectors (PDs) fabricated by ZnGa 2 O 4 thin film. Accelerating life test (ALT) has been examined for UVC PDs. A non-destructive post-treatment method with oxygen supercritical fluid (SCFO) DUV PDs repair. DFT-GGA calculations were used to explain the relationship between formation energies defects in treatment. For semiconductor device applications such as FinFET, MEMS, 2D materials, and wide bandgap reliability is one most powerful key...
Leptospirosis, caused by pathogenic spirochetes of the Leptospira genus, is a common zoonosis in tropical and subtropical regions can lead to an epidemic following heavy rainfall or flooding. The primary reservoirs include rodents, wild animals, dogs, cats, amphibians, others, but brown rat (Rattus norvegicus) remains main source human Leptospirosis. Humans are often accidental hosts they be infected through cuts, abrasions, mucosa, conjunctiva, ingesting contaminated water. clinical...
Molecular recognition (e.g., antigen–antibody, DNA–DNA, and streptavidin–biotin) is a generic, yet highly versatile powerful strategy employed in enzyme-catalyzed signal amplification process. However, this approach not applicable to metals, anions, small reactive species O2– F–), as these molecules are too bind effectively the macromolecules. In paper, we demonstrate an based on controlled binding between streptavidin target activated affinity-switchable biotin (ASB) probes, for detection...