Xia Li

ORCID: 0000-0003-2308-6057
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About
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Research Areas
  • Dementia and Cognitive Impairment Research
  • Functional Brain Connectivity Studies
  • Traditional Chinese Medicine Analysis
  • Alzheimer's disease research and treatments
  • Health disparities and outcomes
  • Mathematics Education and Teaching Techniques
  • Chromatography in Natural Products
  • Traditional Chinese Medicine Studies
  • Education Methods and Practices
  • Stroke Rehabilitation and Recovery
  • Aging, Elder Care, and Social Issues
  • Intergenerational Family Dynamics and Caregiving
  • Geriatric Care and Nursing Homes
  • Education and Work Dynamics
  • Cognitive and developmental aspects of mathematical skills
  • Medicinal Plant Pharmacodynamics Research
  • Knowledge Management and Sharing
  • Teacher Education and Leadership Studies
  • Natural product bioactivities and synthesis
  • Emotion and Mood Recognition
  • Globalization and Cultural Identity
  • Image and Video Quality Assessment
  • Career Development and Diversity
  • Glycosylation and Glycoproteins Research
  • Plant Toxicity and Pharmacological Properties

Anhui University
2025

Kunming Medical University
2025

Shanghai Jiao Tong University
2011-2024

Shanghai Mental Health Center
2011-2024

Brooklyn College
2015-2024

City University of New York
2015-2024

Lishui Central Hospital
2024

Wenzhou Medical University
2016-2024

National Institute for Health and Care Excellence
2019-2021

Chongqing Normal University
2021

A large number of longitudinal studies population-based ageing cohorts are in progress internationally, but the insights from these into risk and protective factors for cognitive conditions like mild impairment dementia have been inconsistent. Some problems confounding this research can be reduced by harmonising pooling data across studies. COSMIC (Cohort Studies Memory an International Consortium) aims to harmonise international cohort ageing, order better understand determinants...

10.1186/1471-2377-13-165 article EN cc-by BMC Neurology 2013-11-06

Objective The reliability and validity of the Chinese version neuropsychiatric inventory (CNPI) in patients with Alzheimer's disease (AD) have not been assessed mainland China. We do research about CNPI China present study. Methods was administered to 219 caregivers AD. Each caregiver retested 4 weeks after initial testing. Results Cronbach's α coefficient total symptom scale 0.69. distress subscale 0.72. entire 0.82. test–retest coefficients ranged from 0.66 0.98 ( p < 0.001). Principal...

10.1002/gps.2757 article EN International Journal of Geriatric Psychiatry 2011-07-18

Abstract Objective: To assess the knowledge of and attitudes towards dementia among Shanghai residents. Methods: A 10‐item optional questionnaire relating to was developed for project. Questionnaires were randomly distributed 1806 families, each family had one respondent. Results: total 1531 questionnaires available. Among them, 45% considered ‘dementia is a normal part ageing’ 29–41% correctly identified symptoms mild dementia. Of respondents, 43% indicated that they would not be ashamed...

10.1111/j.1479-8301.2010.00349.x article EN Psychogeriatrics 2011-06-01

Neonatal brain hypoxia-ischemia (HI) is proved to cause white matter injury (WMI), which resulted in behavioral disturbance. Myelin formed by oligodendrocytes vulnerable (HI), regulating motor and cognitive function, easily damaged HI causing myelin loss. 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8) has a potential rescue role neuronal death post HI. Studies reported that ferroptosis could be induced linked abnormalities. However, the effect of TDZD-8 on WMI its involvement...

10.1016/j.expneurol.2025.115262 article EN cc-by Experimental Neurology 2025-04-01

The ancient Chinese medical texts have recorded Guizhi Fuzi decoction (GZFZT) as a therapeutic intervention for lumbar disc herniation (LDH), and its clinical efficacy has been validated in practice. This research endeavor is specifically designed to delve into elucidate precise underlying mechanisms of action, leveraging the sophisticated methodologies network pharmacology bioinformatics. In this study, we used Traditional Medicine Systems Pharmacology Database Analysis Platform extract...

10.1097/md.0000000000041917 article EN cc-by-nc Medicine 2025-03-21

Research Findings: The present study involved using a questionnaire to investigate the mathematics teaching practices of 74 U.S. and 67 Chinese early childhood teachers. Quantitative qualitative analyses yielded several key findings. First, teachers are less intentional in than their counterparts. Specifically, 27% participants did not set any goals for mathematics, 20% use curriculum or resources. In contrast, 3% fell into each these categories. Second, content United States appears be...

10.1080/10409289.2015.994464 article EN Early Education and Development 2015-01-22

Early screening of cognitive function is critical to dementia treatment and care. However, traditional tests require face-to-face administration are often limited by implementation costs biases.This study aimed assess whether the Thoven Cognitive Self-Assessment (TCSA), a novel, innovative two-step touchscreen-based cognition assessment tool, could identify early impairment due in older adults.The TCSA was administered 61 healthy controls (HCs), 46 participants with mild (MCI) 44 diagnosed...

10.1136/gpsych-2022-100837 article EN cc-by-nc General Psychiatry 2023-02-01

ABSTRACT Background: Disclosing the diagnosis of Alzheimer's disease (AD) to a patient is controversial. There significant stigma associated with AD or dementia in China, but attitude society toward disclosure such had not been formally evaluated prior our study. Therefore, we aimed evaluate disclosing an patients China cognitive impairment from their caregivers, and factors that may affect attitude. Methods: We designed 17-item questionnaire administered this who accompanied three major...

10.1017/s1041610217001132 article EN cc-by-nc-nd International Psychogeriatrics 2017-06-29

Abstract To support people with dementia to live at home, a key national and international policy driver is create dementia-friendly communities which draws attention the importance of local neighbourhood living well dementia. However, there lack evidence about how define interact their neighbourhood. This longitudinal narrative research aimed uncover meaning, construction place in lives care partners through participatory approach. Five couples, where one partner had an early diagnosis...

10.1017/s0144686x1900117x article EN Ageing and Society 2019-09-16

Objective In China, cognitive impairment has become a huge challenge owing to the rapid aging process. We investigate health expectancy and potential factors leading inequalities of for Chinese older people. Methods The study included 19 943 participants aged 65 95 at first observation in Longitudinal Healthy Longevity Survey collected during 2002‐2014. Cognitive was categorized into none, mild, severe by score cMMSE. Multistate models based on continuous‐time Markov process were applied...

10.1002/gps.4966 article EN International Journal of Geriatric Psychiatry 2018-09-11

In China, preschool curriculum has undergone reform and profound changes. Much remains unknown, however, regarding teachers' teaching beliefs after 30 years of adaptation. This study aimed to address the issue investigate concerning mathematics. Twelve teachers in China participated study: they watched videos mathematics lessons conducted US were interviewed with questions lessons. Qualitative analysis was then applied; themes searched from participants' responses. The revealed that Chinese...

10.1080/09575146.2016.1228615 article EN Early Years Journal of International Research and Development 2016-09-12

Glycosylation is involved in several biological processes, and its alterations can reflect the process of certain diseases. Type 2 diabetes mellitus (T2DM) has attained status a global pandemic; however, difference salivary protein glycosylation between healthy subjects patients with T2DM not been fully understood. In present study, specimens from (n = 72) volunteers (HVs, n 80) were enrolled divided into discovery validation cohorts. A method combining lectin microarray blotting was...

10.1039/d0ra05466f article EN cc-by-nc RSC Advances 2020-01-01

Background: The occurrence rate of primary ocular adnexal lymphoma (POAL) is relatively low, and estimation prognosis these patients poses significant challenges. This study aims to investigate the independent prognostic factors POAL establish a predictive model provide clinical data for formulation standardized treatment plans.

10.21037/tcr-23-1556 article EN Translational Cancer Research 2024-02-01

Research Findings: The aim of this study was to investigate U.S. preschool teachers' math pedagogical content knowledge in number comparison. Seventy-four in- and pre-service teachers completed a set scenario-based questions from researcher-designed questionnaire that is composed learning scenarios. Through mixed-method approach, the revealed following findings: considerable portion participants (89%) successfully identified concept comparison embedded scenario, showcasing their specialized...

10.1080/10409289.2024.2389362 article EN Early Education and Development 2024-08-06

China has more cases of Alzheimer's disease (AD) than any other country in the world. As training to recognize and manage dementia is its early stage, it important study clinicians' current prescription preferences for treating patients with AD.This surveyed neurologists, psychiatrists, general physicians (GPs) Shanghai who had outpatients AD, using a questionnaire asking about their these patients.Among 148 clinicians study, 26.4 % were 44.6 29.1 GPs. The groups did not differ significantly...

10.1186/s40035-016-0055-3 article EN cc-by Translational Neurodegeneration 2016-04-25

Cassiae Semen is a common traditional Chinese medicine, and contents of anthraquinones different significantly from area to area. According Pharmacopoeia (2010 edition), only aurantio obtusin chrysophanol were used evaluate the quality Semen, another data could be added later. Ten batches areas determined, total anthraquinones, free combined assessed by ultraviolet visible spectrophotometer, obtusin, rhein, aloe emodin, physcion determined HPLC. After that, principal components analysis was...

10.4268/cjcmm20151319 article EN China Journal of Chinese Materia Medica 2015-07-01
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