Debasish Das

ORCID: 0000-0003-2340-1301
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver Diseases and Immunity
  • Liver Disease and Transplantation
  • Coronary Interventions and Diagnostics
  • Cardiac Arrhythmias and Treatments
  • Hepatitis B Virus Studies
  • Organ Transplantation Techniques and Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Imaging and Diagnostics
  • Colorectal Cancer Screening and Detection
  • Pediatric Hepatobiliary Diseases and Treatments
  • Esophageal Cancer Research and Treatment
  • Cardiac Valve Diseases and Treatments
  • Esophageal and GI Pathology
  • Atrial Fibrillation Management and Outcomes
  • Gallbladder and Bile Duct Disorders
  • Cerebrovascular and Carotid Artery Diseases
  • Anorectal Disease Treatments and Outcomes
  • Gastric Cancer Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Prenatal Screening and Diagnostics
  • Diverticular Disease and Complications
  • Ion channel regulation and function
  • Folate and B Vitamins Research
  • Iron Metabolism and Disorders

Noakhali Science and Technology University
2025

All India Institute of Medical Sciences Bhubaneswar
2021-2024

Institute of Medical Sciences and Sum Hospital
2023-2024

Indian Institute of Technology Jodhpur
2024

Siksha O Anusandhan University
2024

Indian Institute of Technology Indore
2024

Hi-Tech Medical College & Hospital
2023

Kettering General Hospital NHS Trust
2023

Banaras Hindu University
2023

Institute of Medical Sciences
2023

The biochemical response to ursodeoxycholic acid (UDCA)--so-called "treatment response"--strongly predicts long-term outcome in primary biliary cholangitis (PBC). Several prognostic models based solely on the treatment have been developed that are widely used risk stratify PBC patients and guide their management. However, they do not take other variables into account, such as stage of liver disease. We sought improve existing using data from UK-PBC Research Cohort. performed Cox's...

10.1002/hep.28017 article EN Hepatology 2015-07-30
Carla Fiorella Murillo Perez Holly Fisher Shaun Hiu Dorcas Kareithi Femi Adekunle and 95 more Tracy J. Mayne Elizabeth Smoot Malecha Erik C. Ness Adriaan J. van der Meer Willem J. Lammers Palak Trivedi Pier Maria Battezzati Frederik Nevens Kris V. Kowdley Tony Bruns Nora Cazzagon Annarosa Floreani Andrew L. Mason Albert Parés María‐Carlota Londoño Pietro Invernizzi Marco Carbone Ana Lleò Marlyn J. Mayo George Ν. Dalekos Nikolaos K. Gatselis Douglas Thorburn Xavier Verhelst Aliya Gulamhusein Harry L.A. Janssen Rachel Smith Steve Flack Victoria Mulcahy Michael Trauner Christopher L. Bowlus Keith D. Lindor Christophe Corpechot David Jones George Mells Gideon M. Hirschfield James Wason Bettina E. Hansen Richard Sturgess Christopher G. Healey Anton Gunasekera Yiannis Kallis Gavin Wright Thiriloganathan Mathialahan Richard J. Evans Jaber Gasem David Ramanaden Emma Ward Mahesh Bhalme Paul Southern James L. Maggs Mohamed Yousif George Mells Brijesh Srivastava Matthew Foxton Carole Collins Yash Prasad Francisco Porras-Perez Tom Yapp Minesh Patel Roland Ede Martyn Carte Konrad Koss Prayman Sattianayagam Charles Grimley Jude Tidbury Dina Mansour Matilda Beckley Coral Hollywood John Ramag Harriet Gordon Joanne Ridpath Bob Grover George Abouda Ian Rees Mark Narain Imroz Salam Paul Banim Debasish Das Helen Matthews Faiyaz Mohammed Rebecca Jones Sambit Sen G. W. G. Bird Martin Prince Geeta Prasad Paul Kitchen John Hutchinson Prakash C. Gupta David Jones Amir Shah Subrata Saha Katharine Pollock Stephen Barclay Natasha McDonald Simon Rushbrook

Background & AimsThe Primary Biliary Cholangitis (PBC) Obeticholic Acid (OCA) International Study of Efficacy (POISE) randomized, double-blind, placebo-controlled trial demonstrated that OCA reduced biomarkers associated with adverse clinical outcomes (ie, alkaline phosphatase, bilirubin, aspartate aminotransferase, and alanine aminotransferase) in patients PBC. The objective this study was to evaluate time first occurrence liver transplantation or death the POISE open-label extension vs...

10.1053/j.gastro.2022.08.054 article EN cc-by Gastroenterology 2022-09-20

Polluted water has become a concern for the scientific community as it causes many severe threats to living beings. Detection or removal of contaminants present in wastewater and attaining purity that can be used various purposes are primary responsibility. Different treatment methods have already been purification sewage. There is need low-cost, highly selective, reusable materials efficiently remove pollutants purify contaminated water. In this regard, MOFs shown significant potential...

10.1021/acs.langmuir.3c03724 article EN Langmuir 2024-02-28

OBJECTIVES To assess the variation in practice of Barrett's esophagus (BE) management comparison with accepted international guidelines before and after introduction a large BE randomized controlled trial (RCT) protocols including those tissue sampling. DESIGN A validated anonymized questionnaire was sent to 401 senior attending gastroenterologists asking for details their current BE, especially histological Of 228 respondents, 57 individuals (each from different center) were first group...

10.1111/j.1572-0241.2008.01790.x article EN The American Journal of Gastroenterology 2008-04-28

Abstract Background Liver disease is within the top five causes of premature death in adults. Deaths caused by complications cirrhosis continue to rise, whilst deaths related other non-liver areas are declining. Portal hypertension primary sequelae and associated with development variceal haemorrhage, ascites, hepatic encephalopathy infection, collectively termed decompensation, which leads hospitalisation mortality. It remains uncertain whether administering a non-selective beta-blocker...

10.1186/s13063-024-08063-3 article EN cc-by Trials 2024-04-16

Background: Renal dysfunction following cardiac surgery involving cardiopulmonary bypass is associated with considerable morbidity and mortality. Procalcitonin has demonstrated effectiveness as a biomarker for guiding the initiation duration of antibiotic therapy in patients admitted to intensive care units. This study aimed assess procalcitonin predictor acute kidney injury bypass. Methods: prospective observational was conducted at Department Cardiac Surgery, Bangabandhu Sheikh Mujib...

10.36347/sasjs.2025.v11i02.008 article EN SAS Journal of Surgery 2025-02-13

Abstract Background & Aims There is limited information regarding patients with AIH outside relatively few large centres. We describe here the presenting features of , collected as part an audit involving 28 UK hospitals. Methods Patients (incident since 1/1/2007 or prevalent 1/1/2000) were ≥18 years and either met 1999 International Group ( IAIHG ) diagnostic criteria (n = 1164), received immunosuppressive therapy for clinically diagnosed 103). Results Of 1267 (80% women, 91% Caucasian,...

10.1111/liv.13724 article EN Liver International 2018-02-18

OBJECTIVES: Losartan, an angiotensin II receptor blocker, has portal hypotensive effects. This study evaluates the effect of losartan on pressure after 14 days and compares it with that propranolol. METHODS: A total 39 individuals cirrhosis were randomized into two groups 19 20 patients each treated propranolol, respectively. Hepatic venous gradient was measured at baseline day therapy. Responders to therapy had hepatic reduction ≥20% value. RESULTS: With losartan, 15 (78.94%) responders...

10.1111/j.1572-0241.2003.07497.x article EN The American Journal of Gastroenterology 2003-06-01

Mean terminal restriction fragment (TRF) lengths in white blood cells (WBCs) have been previously found to be associated with breast cancer. To assess whether this marker could used as a test for cancer susceptibility women, TRF length was measured 72 treated female patients and 1696 unaffected controls between the ages of 45 77 from Twin Research Unit at St Thomas' Hospital, well 140 newly diagnosed cases 108 mammographically screened Guy's Hospital. also tested correlation chromosome...

10.1038/sj.bjc.6604085 article EN cc-by-nc-sa British Journal of Cancer 2007-11-13

Abstract Background Carvedilol, a non‐selective beta‐ and α‐1 blocking agent, has portal hypotensive action. This study evaluates the acute 7‐day response to carvedilol, compares it that of propranolol. Methods Thirty‐six cirrhotics were randomized into two groups 18 each, treated with carvedilol or Hepatic venous pressure gradient (HVPG) was measured before 90 min after either 25 mg 80 propranolol administered orally, again 7 days 12.5 daily daily, respectively. ‘Responders’ defined as...

10.1046/j.1440-1746.2002.02674.x article EN Journal of Gastroenterology and Hepatology 2002-02-01

Paracentral acute middle maculopathy (PAMM) is a type of ischemic affecting intermediate and deep retinal capillary plexuses. A typical presentation onset scotoma with or without vision loss. It characterized by greyish-white parafoveal lesions. Sometimes very subtle lesions can be missed on clinical examination. The main diagnostic modality spectral domain optical coherence tomography (SD-OCT) wherein focal multifocal are seen as bands hyperreflectivity in the inner nuclear outer plexiform...

10.7759/cureus.35418 article EN Cureus 2023-02-24
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