- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Healthcare Systems and Reforms
- Diagnosis and treatment of tuberculosis
- Bipolar Disorder and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- HIV/AIDS Impact and Responses
- Global Health and Epidemiology
- Healthcare cost, quality, practices
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
Department of Health
2019-2024
Tuberculosis (TB) and non-communicable diseases (NCD) share predisposing risk factors. TB-associated NCD might cluster within households affected with TB requiring shared prevention care strategies. We conducted an individual participant data meta-analysis of national prevalence surveys to determine whether in members TB. identified eligible that reported at least one or factor through the archive maintained by World Health Organization searching Medline Embase from 1 January 2000 10 August...
Setting The 3 rd national tuberculosis (TB) survey in the Philippines 2007 reported a significant decline prevalence of TB. Since then, more investments for TB control have been made, yet burden estimates from routine surveillance data remain relatively stable. Objective To estimate bacteriologically confirmed pulmonary amongst individuals aged ≥15 years 2016. Design In March–December 2016, we conducted population-based with stratified, multi-stage cluster sampling residents 106 clusters...
Tuberculosis (TB) is a disease associated with poverty. Moreover, significant proportion of TB patients face substantial financial burden before and during care. One the top targets in End strategy was to achieve zero catastrophic costs due by 2020. To assess patient related care TB-affected households that faced costs, Philippines National Programme (NTP) conducted national cost survey 2016-2017. A cross-sectional 1,912 taking treatment health facilities engaged NTP. The sample consists 786...
BackgroundNon-communicable diseases (NCDs) and NCD risk factors, such as smoking, increase the for tuberculosis (TB). Data are scarce on of prevalent TB associated with these factors in context population-wide systematic screening association between NCDs different manifestations TB, where ∼50% being asymptomatic but bacteriologically positive (subclinical). We did an individual participant data (IPD) meta-analysis national sub-national prevalence surveys to synthesise evidence symptomatic...
<sec><title>BACKGROUND</title>Poor treatment outcomes among people with drug-resistant TB (DR-TB) are a major concern. Heteroresistance (presence of susceptible and resistant Mycobacterium tuberculosis in the same sample) has been identified some TB, but its impact on is unknown.</sec><sec><title>METHODS</title>We used targeted deep sequencing to identify mutations associated DR-TB heteroresistance culture samples 624 DR-TB. We evaluated association...
BACKGROUND: The Philippines aims to accelerate TB reduction through the provision of universally accessible and affordable services. objectives this paper are estimate costs services interventions using a health systems´ perspective, explore cost differences in service delivery via primary care facilities or hospitals. METHODS: Data were collected from multi-stage stratified random sampling 28 accordance with Global Health Cost Consortium costing standards analysis tools. Unit (in US$)...
Ambitious efforts to detect and treat tuberculosis (TB) are required reduce the burden of disease in low resource settings, provision high quality TB services is critical reaching global targets. The assessment (QTSA) a facility-based approach aimed at identifying gaps prioritizing interventions improve care across multiple countries with burden. Randomly sampled facilities assessed standardized instruments collect data on structures, processes, outcomes care, adaption for local diagnostic...
Policies implemented to slow transmission of COVID-19 are expected have disrupted delivery routine health services, including tuberculosis (TB) care.We analyzed daily counts drug-susceptible (DS)-TB case notifications from all facilities affiliated with the Philippines National TB Program (NTP) before and after implementation community quarantine (January 1-December 31, 2020). Using an interrupted time series design, we assessed immediate sustained effects on reporting. 2019 WHO estimates...
High levels of treatment adherence are critical for achieving optimal outcomes among patients with tuberculosis (TB), especially drug-resistant TB (DR TB). Current tools identifying high-risk non-adherence insufficient. Here, we apply trajectory analysis to characterize behavior early in DR and assess whether these patterns predict outcomes.We conducted a retrospective Philippines treated between 2013 2016. To identify unique adherence, performed group-based modelling on the first 12 weeks...
This study was to meet a practical need design simple tool identify TB patients who may potentially be facing catastrophic costs while seeking care in the public sector. Such help prevent and address among individual patients.We used data from national patient cost survey Philippines. We randomly allocated either derivation or validation sample. Using adjusted odds ratios (ORs) β coefficients of logistic regression, we developed four scoring systems validated each system sample.We identified...
This paper aimed to determine the facilitating and hindering factors in implementation of local tuberculosis (TB) control programs two purposively selected localities Province Laguna, Philippines. Transcripts semi-structured interviews with six policymakers program implementers at regional, provincial, city/municipal levels were qualitatively analyzed accordance method Miles co-authors validated through triangulation informant/stakeholder feedback. Identified include 1) allocation...
Abstract Introduction High levels of treatment adherence are critical for achieving optimal outcomes among patients with tuberculosis (TB), especially drug-resistant TB (DR TB). Current tools identifying high-risk non-adherence insufficient. Here, we apply trajectory analysis to characterize behavior early in DR and assess whether these patterns predict outcomes. Methods We conducted a retrospective Philippines treated between 2013 2016. To identify unique adherence, performed group-based...