Shushan Zhang

ORCID: 0000-0003-2401-6587
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Sperm and Testicular Function
  • Ultrasound in Clinical Applications
  • Genetic and phenotypic traits in livestock
  • Reproductive biology and impacts on aquatic species
  • Parkinson's Disease Mechanisms and Treatments
  • Meat and Animal Product Quality
  • Pluripotent Stem Cells Research
  • Noise Effects and Management
  • Advanced Materials and Mechanics
  • Renal and related cancers
  • Hearing Loss and Rehabilitation
  • Autophagy in Disease and Therapy
  • Entrepreneurship Studies and Influences
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Ovarian cancer diagnosis and treatment
  • Neurological diseases and metabolism
  • Nuclear Receptors and Signaling
  • Calcium Carbonate Crystallization and Inhibition
  • Hearing, Cochlea, Tinnitus, Genetics
  • Medicinal Plants and Bioactive Compounds
  • Dementia and Cognitive Impairment Research
  • Cancer-related molecular mechanisms research
  • Animal Genetics and Reproduction
  • Phytoestrogen effects and research

Affiliated Hospital of North Sichuan Medical College
2021-2025

Sun Yat-sen University
2020-2025

Fifth Affiliated Hospital of Sun Yat-sen University
2020-2025

Shanghai Academy of Agricultural Sciences
2015-2025

Beijing Institute of Technology
2021-2024

Ministry of Agriculture and Rural Affairs
2022-2024

Northeast Normal University
2018-2024

Nanchang University
2022-2024

Guilin University of Technology
2024

First Affiliated Hospital of Jiangxi Medical College
2024

This study was conducted to explore the clinical value of noninvasive assessment bedside ultrasound in diagnosis lung lesions Coronavirus Disease-19. In this retrospective study, 30 patients with Disease-19 admitted our hospital from January 18 February 5, 2020, were selected as research subjects. All cases examined by and CT. Lung reviewed blinded observers, imaging scores being used analyze findings chest CT reference standard. The evaluated. signs mainly manifested interstitial pulmonary...

10.1055/a-1154-8795 article DE Ultraschall in der Medizin - European Journal of Ultrasound 2020-04-15

The importance of time-cost-quality trade-off in construction projects has been widely recognized by the industry. In this paper, we develop an integrated optimization model on basis improved time-cost and quality-time models. We improve traditional cost-time taking reward punishment into consideration. Further, build a new quality model, called performance index (QPI), to describe system reliability. avoidance assigning node weights referring expert experience adds practicality calculation....

10.1061/(asce)me.1943-5479.0000189 article EN Journal of Management in Engineering 2013-02-18

Incomplete radiofrequency ablation (IRFA) triggers mild protective autophagy in residual tumor cells and results an immunosuppressive microenvironment. This accelerates the recurrence of tumors causes resistance to anti-PD-1/PDL1 therapy, which bringing a great clinical challenge immunotherapy. Mild activation can promote cancer cell survival while further amplification contributes immunogenic death (ICD). To this regard, we constructed active targeting zeolitic imidazolate framework-8...

10.1186/s12951-023-02067-y article EN cc-by Journal of Nanobiotechnology 2023-10-03

Mitochondria hold redox homeostasis and energy metabolism as a crucial factor during oocyte maturation, while the exposure of estrogenic mycotoxin zearalenone causes developmental incapacity in porcine oocyte. This study aimed to reveal potential resistance phytoalexin resveratrol against maturation whether its mechanism was related with PTEN-induced kinase 1 (PINK1)/Parkin-mediated mitophagy. Porcine oocytes were exposed 20 μM or without 2 vitro maturation. As for results, impaired...

10.3390/toxins14090641 article EN cc-by Toxins 2022-09-16

Abstract Parkinson's disease (PD) is the most prevalent neurodegenerative disorder. Neuroinflammation mediated by activated microglia and apoptosis of dopaminergic (DA) neurons in midbrain are its primary pathological manifestations. Leucine‐rich repeat protein kinase 2 (LRRK2) has been observed to increase expression during neuroinflammation, however, effect LRRK2 on activation remains poorly understood. In this study, we have established lipopolysaccharide (LPS) treated BV2 cells...

10.1002/jcp.31250 article EN Journal of Cellular Physiology 2024-03-13

A major characteristic of ovarian cancer (OC) is its unique route metastasis via ascites. The immune microenvironment in ascites remains understudied, leaving the mechanism ascites-mediated abdominal obscure. Here, a single-cell transcriptomic landscape CD45+ cells across multiple anatomical sites depicted, including primary tumors, metastatic lesions, and ascites, from patients diagnosed with high-grade serous carcinoma (HGSOC). novel subset perilipin 2 high (PLIN2hi) macrophages are...

10.1002/advs.202411314 article EN cc-by Advanced Science 2025-02-07

High-intensity noise is associated with noise-induced hearing loss (NIHL). There also evidence that exposure related to cognitive impairment. This research aimed analyze the associations and potential pathways of cumulative (CNE), A total 560 subjects were included in this from May 2021 April 2022 western China. The demographic features, occupational CNE investigated examined. Hearing was evaluated according National standard GB/T 7583-1987 Mini-Mental State Examination (MMSE) Montreal...

10.3389/fpubh.2025.1455340 article EN cc-by Frontiers in Public Health 2025-02-19

The present study aimed to investigate the impact of different concentrations (0%, 0.5%, 1.0%, 1.5%, and 2.0%) nano-soybean lecithin (SL) in extender on sperm quality, motion characteristics, fertility outcomes post-thawed rooster semen. Adult Ross broiler breeder roosters (n = 20) were subjected semen collections twice a week for three weeks. At each collection, samples pooled allocated into five treatments corresponding nano-SL (control, SL0.5, SL1.0, SL1.5, SL2.0). Sperm parameters,...

10.3390/ani11061769 article EN cc-by Animals 2021-06-13

Hu sheep is a valuable breed in China, and semen cryopreservation of important for sustainable development the agri-food industry. This study aimed to evaluate effect thawing rate antioxidants (procyanidins [PC] mitoquinone [MitoQ]) on quality antioxidant enzyme activity post-thaw sperm sheep. Our results showed that highest was obtained from group thawed at 70°C 5 seconds. Furthermore, addition 150 nM MitoQ extender could enhance motility, integrity membrane acrosome, mitochondrial...

10.1089/bio.2020.0067 article EN Biopreservation and Biobanking 2021-02-24

Designing materials and structures with high energy absorption self-recoverability remains a challenge for reusable absorption, particularly in aerospace engineering applications (i.e., planetary landers). While the prevalent design methods of absorbers mainly use mechanical instability tilted curved beams, limited capabilities low strength or beams limit performance improvement. In nature, Phlorodes diabolicus has evolved extreme impact resistance, which suture interface structure plays key...

10.1021/acsami.3c06463 article EN ACS Applied Materials & Interfaces 2023-08-10

In order to protect the spermatozoa against cold shock, hen egg yolk is widely used as a cryoprotective agent in semen freezing extenders for domestic animals.The protective action of largely presumed be due low density lipoproteins (LDL).The effects LDL on sperm quality bull and northern pike (Esox lucius) after freezing-thawing have been reported, but no study has made evaluate effect boar motility other characteristics.The experiment was carried out investigate 0.25 ml straws.The aim...

10.5713/ajas.2006.486 article EN cc-by Asian-Australasian Journal of Animal Sciences 2006-02-01

Manufacturing enterprises have realized that organizational learning is conducive to the development of environmental and economic sustainability. However, prior literature has paid less attention how green orientation affects sustainable performance. Based on theory, this article constructs a moderated mediating model impact performance, using innovation behavior as variable corporate social responsibility (CSR) moderating variable. Through empirical analysis 193 valid questionnaires from...

10.3390/su14137933 article EN Sustainability 2022-06-29

In this study, we explore the effects of Poria cocos mushroom polysaccharides (PCPs) on quality and DNA methylation cryopreserved spermatozoa Shanghai white pigs. A total 24 ejaculates (three ejaculate samples per boar) from eight pigs were manually collected. The pooled semen was diluted with a based extender supplemented different concentrations PCPs (0, 300, 600, 900, 1200, 1500 μg/mL). Once thawed, their antioxidant function assessed. meantime, effect also analyzed. results show that...

10.3390/cells12111456 article EN cc-by Cells 2023-05-24
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