A5061899703- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Central Venous Catheters and Hemodialysis
- Hepatocellular Carcinoma Treatment and Prognosis
- Cerebrovascular and Carotid Artery Diseases
- Renal and Vascular Pathologies
- Liver Disease Diagnosis and Treatment
- Diagnosis and Treatment of Venous Diseases
- Kidney Stones and Urolithiasis Treatments
- Dialysis and Renal Disease Management
- Liver Disease and Transplantation
- Vascular Anomalies and Treatments
- Aortic aneurysm repair treatments
- Medical Imaging and Pathology Studies
- Vascular anomalies and interventions
- Peripheral Nerve Disorders
- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Ureteral procedures and complications
- Diabetic Foot Ulcer Assessment and Management
- Organ Transplantation Techniques and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Esophageal and GI Pathology
- Advanced X-ray and CT Imaging
Singapore General Hospital
2014-2024
Sengkang General Hospital
2024
Duke-NUS Medical School
2019-2022
SingHealth
2022
SingHealth Duke-NUS Academic Medical Centre
2020-2021
National Heart Centre Singapore
2019
Mount Elizabeth Hospital
2018
Mount Sinai Hospital
2008
University Health Network
2008
St Thomas' Hospital
2005
Coincidence imaging of low-abundance yttrium-90 (90Y) internal pair production by positron emission tomography with integrated computed (PET/CT) achieves high-resolution post-radioembolization microsphere biodistribution. Part 2 analyzes tumor and non-target tissue dose-response 90Y PET quantification evaluates the accuracy 99mTc macroaggregated albumin (MAA) single-photon CT (SPECT/CT) predictive dosimetry.Retrospective dose resin microspheres was performed on same 23-patient data set in...
Background & AimsHepatocellular carcinoma (HCC) is often associated with hepatitis B virus (HBV) infection. Cells of most HBV-related HCCs contain HBV-DNA fragments that do not encode entire HBV antigens. We investigated whether these integrated epitopes are recognized by T cells and their presence in can be used to select HBV-specific T-cell receptors (TCRs) for immunotherapy.MethodsHCC negative antigens, based on immunohistochemistry, were analyzed the messenger RNAs (mRNAs) real-time...
Yttrium-90 (90Y) positron emission tomography with integrated computed (PET/CT) represents a technological leap from 90Y bremsstrahlung single-photon (SPECT/CT) by coincidence imaging of low abundance internal pair production. Encouraged favorable early experiences, we implemented post-radioembolization PET/CT as an adjunct to SPECT/CT in diagnostic reporting.This is retrospective review all paired and scans over 1-year period. We compared image resolution, ability confirm technical success,...
Purpose To compare lesion primary patency and restenosis rates between drug-eluting balloon (DEB) percutaneous transluminal angioplasty (PTA) conventional PTA (cPTA) in the treatment of arteriovenous fistula (AVF) graft (AVG) stenosis. Materials Methods In this prospective study, 119 participants (mean age, 59.2 years; 79 men, 40 women) with failing AVFs (n = 98) or AVGs 21) were randomly assigned to undergo either DEB 59) cPTA 60) from January 2012 May 2013. Primary end points at 6 months;...
Background There is a paucity of randomized trials demonstrating superior efficacy drug-coated balloon angioplasty (DCBA) compared with conventional percutaneous transluminal (PTA) for below-the-knee arterial disease in patients critical limb ischemia. Purpose To compare DCBA versus PTA lesions participants critical ischemia through 12 months. Materials and Methods In this prospective, randomized, two-center, double-blind superiority study, rest pain or tissue loss atherosclerotic the...
Hepatic venous pressure gradient (HVPG) is the gold-standard for measurement of portal hypertension, a common cause life-threatening conditions such as variceal bleeding and hepatic encephalopathy. HVPG also plays crucial role in risk stratification, treatment selection assessment response. Thus recognition pitfalls unusual crucial. This article aims to provide radiographical clinical guide with representative cases.
Introduction: C-arm Cone Beam CT (CBCT) is a technology that being integrated into many of the newer angiography systems in interventional suite. Due to its ability provide cross sectional imaging, it has opened myriad opportunities for creating new clinical applications. We review technical aspects, current reported applications and potential benefits this technology. Materials Methods: Searches were made via PubMed using string “CBCT”, “Cone CT”, Computed Tomography” “C-arm Tomography”....
Acute limb ischemia is associated with significant mortality and amputation rate. Early restoration of flow can be obtained by various treatment methods that include catheter-directed thrombolysis (CDT) percutaneous mechanical thrombectomy (PMT). These treatments have been shown to effective but complications. There lack data comparing these two treatments. We aim review our experience in the acute (ALI) compare CDT PMT.A total 94 patients [mean age 65 years, 67% male (n = 63)] presented ALI...
Objective: Diabetic foot ulcer (DFU) is a common complication in patients with diabetes. With current treatment, only two-thirds of heal, median duration 3–6 months. Hard-to-heal DFUs are major source morbidity and mortality. Improving wound healing via soft tissue reconstruction may be the key to improving clinical outcomes. Thus, Limb Salvage (DLS) service Sengkang General Hospital, Singapore, was established provide streamlined, one-stop, comprehensive dedicated DFU reconstruction. The...
Percutaneous transluminal angioplasty is the current standard treatment for arteriovenous fistula (AVF) stenosis. The mid- and long-term patency with plain balloon (PBA) however far from satisfactory. While paclitaxel-coated has been shown to be superior PBA, concern over its safety profile recently arisen after a reported possible increased mortality risk meta-analysis of large lower limb studies. An new type drug coating, sirolimus-coated (SCB), proven improve in coronary arteries....
Abdominal aortic aneurysm (AAA) is a common degenerative condition affecting the elderly population. Rupture carries high overall mortality. Elective endovascular stent graft repair well described. We describe patient with ruptured AAA and co-morbid conditions making him unfit for surgery general or epidural anaesthesia, who was successfully treated by under local anaesthesia.
Purpose: To report a candy-plug technique using Zenith Alpha stent-graft to occlude the distal false lumen in patient with complicated chronic type B aortic dissection. Case Report: A 50-year-old male smoker presented chest pain due rapidly growing Computed tomography angiography (CTA) showed dissection extending from origin of left subclavian artery (LSA) down femoral artery. There was fusiform aneurysmal dilatation proximal descending aorta measuring up 5.8 cm diameter. He underwent...
Real-world management of patients with hepatocellular carcinoma (HCC) is crucially challenging in the current rapidly evolving clinical environment which includes need for respecting patient preferences and autonomy. In this context, regional/national treatment guidelines nuanced to local demographics have increasing importance guiding disease management. We report here real-world data on outcomes HCC from a validation Consensus Guidelines at National Cancer Centre Singapore (NCCS).We...