A5100358169- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Endometriosis Research and Treatment
- Reproductive Biology and Fertility
- Minimally Invasive Surgical Techniques
- Ovarian cancer diagnosis and treatment
- Cancer Immunotherapy and Biomarkers
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Thyroid Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Pelvic floor disorders treatments
- Renal and related cancers
- Cervical Cancer and HPV Research
- Gut microbiota and health
- Radiomics and Machine Learning in Medical Imaging
- Dysphagia Assessment and Management
- Maternal and fetal healthcare
- Colorectal and Anal Carcinomas
- Menopause: Health Impacts and Treatments
- Myasthenia Gravis and Thymoma
- Lipoproteins and Cardiovascular Health
- Gastric Cancer Management and Outcomes
- Bariatric Surgery and Outcomes
- Anatomy and Medical Technology
Korea University
2012-2025
Chungnam National University Hospital
2015-2025
Seoul National University
2025
Seoul National University Bundang Hospital
2024
CHA University
2012-2024
Dankook University
2022-2024
University of Missouri–Kansas City
2024
National Health Insurance Service Ilsan Hospital
2007-2023
Sunchon National University
2022-2023
Harvard University
2023
The goal of this study was to evaluate the effect Roux-en-Y gastric bypass (RYGBP) on 2 metabolic disorders, diabetes and dyslipidemia, in obese type mellitus (T2DM) patients.Little is known about long-term change lipid profiles T2DM patients after RYGBP.This a retrospective review prospectively collected data glucose metabolism morbidly with antidiabetic medications who underwent laparoscopic RYGBP.A total 219 mean (+/-SD) duration follow-up 26.4 (+/-12.8) months were included study. At one...
Human epidermal growth factor receptor-2 (HER2) and 3 (HER3) belong to the receptor (EGFR) family of transmembrane tyrosine kinases. In this study, we assessed HER2/HER3 expression levels in specimens epithelial ovarian cancer determined their correlation with clinical features cancer.
The accuracy of colposcopic diagnosis depends on the skill and proficiency physicians. This study evaluated feasibility interpreting images with assistance artificial intelligence (AI) for high-grade cervical intraepithelial lesions. included female patients who underwent colposcopy-guided biopsy in 2020 at two institutions Republic Korea. Two experienced colposcopists reviewed all separately. Cerviray AI® system (AIDOT, Seoul, Korea) was used to interpret images. AI demonstrated improved...
Abstract Adult thyroid dysfunction is a common endocrine disorder associated with an increased risk of cardiovascular disease and mortality. A recent epidemiologic study revealed link between obesity prevalence hypothyroidism. It conceivable that excessive adiposity in might lead to expansion the interfollicular adipose (IFA) depot or steatosis follicular cells (thyroid steatosis, TS). In this study, we investigated morphological functional changes glands obese humans animal models,...
It is well-known that policosanol can improve serum lipid profiles, although the physiological mechanism still unknown. Here, we investigated functional and structural changes in lipoproteins after consumption of policosanol. To investigate effect policosanol, analyzed parameters young non-smoker (YN; n=7, 24.0±2.4 years), smoker (YS; 26.3±1.5 middle-aged subjects (MN; n=11, 52.5±9.8 years) who consumed daily (10 mg/day) for 8 weeks. After weeks, systolic blood pressure was significantly...
BackgroundSulfadoxine-pyrimethamine (SP) antimalarial therapy has been suggested to potentially increase the birth weight of infants in pregnant women sub-Saharan Africa, independently malarial infection. Here, we utilized female intestinal organoid-derived cells cultured within microfluidic Organ Chips investigate whether SP could directly impact function and thereby improve absorption essential fats nutrients crucial for fetal growth.MethodsUsing a human organ-on-a-chip model, replicated...
Abstract Background The gut microbiota plays a pivotal role in maintaining intestinal homeostasis and mitigating inflammation. orphan nuclear receptor ESRRA (estrogen-related alpha) has been identified as critical regulator of mitochondrial function autophagy, yet its modulation health remains unclear. Methods We investigated using Esrra-deficient mice dextran sodium sulfate (DSS)-induced colitis model. Colitis severity is through survival rate body weight. Gut barrier was evaluated...
Abstract Background: The study aims to investigate the role of TIGIT in immunosuppressive environment and evaluates potential blockade (αTIGIT) improve antitumor immune responses. Methods: We analyzed public transcriptomic data identify expression patterns on T cells breast cancer its prognostic impact. In addition, a murine TNBC model was utilized evaluate effects PD-1 (αPD-1), local RT, αTIGIT. tumors, tumor-draining lymph nodes (TdLNs), spleen were assess responses upon treatments....
The Da Vinci 5 is the latest advancement in robotic-assisted surgery, offering significant improvements vision, ergonomics, and surgical efficiency. With enhanced image quality, auto smoke evacuation, force feedback technology, it addresses key limitations of previous models. introduction digital swap a watt-based generator further streamlines workflows. Initial experiences suggest that these innovations contribute to safer more precise minimally invasive procedures. Future software updates...
The anti-tumor efficacy of PD-1 blockade and local radiotherapy (RT) is often limited by diverse mechanisms that suppress CD8+ T cell responses. Lymphocyte-activation gene 3 (LAG-3) an inhibitory receptor expressed on exhausted cells regulatory (Tregs), its has been shown to enhance the effects blockade. Therefore, we hypothesized combining LAG-3 with RT would overcome treatment resistance in triple-negative breast cancer (TNBC). Using 4T1 syngeneic mouse TNBC model, evaluated immune...
Purpose: The purpose of this study was to develop a lesson plan related simulation for nursing students by understanding what relationship learning satisfaction, self-efficacy and attitude have after applying simulation-based education on emergency care. Methods: Simulation practice, seminar, class group self-study about patient having myocardial infarction were applied 5 weeks. After the care, rated their attitude, satisfaction sense with self-administered questionnaire academic achievement...
The purpose of this study was to evaluate risk factors vaginal cuff dehiscence or evisceration according the type operation.Medical records 604 women who underwent hysterectomies at Korea University Anam Hospital between June 2007 and 2011 were reviewed. They allocated six groups. types included robotic hysterectomy (n = 7), radical node dissection (RRHND, n 9), total laparoscopic (TLH, 274), laparoscopy assisted (LAVH, 238), 11), abdominal (ARH, 63). characteristics outcomes each groups...
Only a few studies have reported the learning curve for sentinel lymph node (SLN) detection in gynecologic malignancies. We investigated SLN during robot-assisted laparoscopic surgery endometrial and cervical carcinomas.This retrospective analysis included patients with stage IA to IIA1 cancer or I III who underwent mapping using indocyanine green performed by single surgeon. Learning curves were analyzed consecutive cases rates cumulative sum (CUSUM) method.SLN was achieved 81.25% (65/80),...
Recent prospective studies have shown poorer oncologic outcomes following minimally invasive surgery, which has led many surgeons to deeply inspect their practices. We reviewed our experience and evaluated the results of radical hysterectomy in patients with early stage cervical cancer. This retrospective study included cancer (Ia1 - IIa1) who were treated from May 2006 Dec 2016. Patients divided into three groups according surgical approach: abdominal (RAH), laparoscopic (LRH),...
Do single nucleotide polymorphisms (SNPs) or synergistic interactions between SNPs and diplotypes within the insulin-like growth factor 2 receptor (IGF2R) ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19), contribute to premature ovarian failure (POF)? Synergistic were detected SNPs, including a non-synonymous SNP, IGF2R ADAMTS19 which may POF; however, there was no correlation POF in SNP model after Bonferroni correction. regulates free IGF2 level, is involved...
Objective The aim of this study was to compare and determine the feasibility, surgical outcomes, learning curves robotic radical hysterectomy with lymph node dissection (RRHND) conventional laparoscopic (LRHND) performed by a single surgeon, in patients cervical cancer. Methods Between April 2009 March 2013, 22 underwent LRHND 19 RRHND. Variables such as age, body mass index, International Federation Gynecology Obstetrics stage, histological results, number dissected nodes, operative time,...
Colposcopy is the gold standard diagnostic tool for identifying cervical lesions. However, accuracy of colposcopies depends on proficiency colposcopist. Machine learning algorithms using an artificial intelligence (AI) system can quickly process large amounts data and have been successfully applied in several clinical situations. This study evaluated feasibility AI as assistive diagnosing high-grade intraepithelial neoplasia lesions compared to human interpretation images. two-centered,...
Purpose: In comminuted intertrochanteric fractures, various operative options have been introduced.The purpose of this study was to determine whether there were differences in clinical and radiologic outcomes among bipolar hemiarthroplasty (BH), compression hip screw (CHS) proximal femur nail antirotation (PFNA) treating fractures (AO/OTA classification, A2 [22, 23]) Materials Methods: We retrospectively evaluated total 150 patients (BH, 50; CHS, PFNA, 50) who operated due from March 2010...