A5074084744- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Surfactants and Colloidal Systems
- Liver Disease and Transplantation
- Pickering emulsions and particle stabilization
- Clinical Nutrition and Gastroenterology
- Renal cell carcinoma treatment
- Nutrition and Health in Aging
- Enhanced Oil Recovery Techniques
- Hepatitis C virus research
- Cancer Immunotherapy and Biomarkers
- Child Nutrition and Feeding Issues
- Proteins in Food Systems
- Electrohydrodynamics and Fluid Dynamics
- Cancer Mechanisms and Therapy
- Colorectal Cancer Treatments and Studies
- Accounting and Financial Management
- Pregnancy and preeclampsia studies
- Petroleum Processing and Analysis
- Hepatitis B Virus Studies
- Fluid Dynamics and Mixing
- Dysphagia Assessment and Management
- Analytical Chemistry and Chromatography
- Environmental Chemistry and Analysis
- Advanced Polymer Synthesis and Characterization
Hospital General Universitario Gregorio Marañón
2017-2023
Universidad El Bosque
2022-2023
Flanders Marine Institute
2022
University of the Andes
2000-2021
Technological University of the Mixteca
2018-2019
Hospital Universitario Infanta Cristina
2000-2015
Parc de Salut
2014
University of Chile
2007-2009
Hospital San Borja Arriarán
2009
Hospital General Yagüe
2005
The minimum interfacial tension occurrence along a formulation scan at the so-called optimum is discussed to be related curvature. attained inversely proportional domain size of bicontinuous microemulsion and layer rigidity, but no accurate prediction available. data from very simple ternary system made pure products accurately follows correlation for formulation, exhibit linear relationship between performance index as logarithm optimum, variables. This relation probably too when number...
Background and Aims Patients with hepatitis C virus (HCV) advanced fibrosis remain at risk of hepatocellular carcinoma (HCC) after sustained viral response (SVR) need lifelong surveillance. Because HCC is not homogenous may decrease regression, we aimed to identify patients low based on the prediction noninvasive markers its changes SVR. Approach Results This a multicenter cohort study, including HCV compensated that achieved SVR direct antivirals. Clinical transient elastography (TE) data...
To evaluate the safety and efficacy of selective internal radiation therapy (SIRT) in combination with a PD-1 inhibitor patients unresectable hepatocellular carcinoma (uHCC) liver-only disease ineligible for chemoembolization.NASIR-HCC is single-arm, multicenter, open-label, phase 2 trial that recruited from 2017 to 2019 who were naïve immunotherapy had tumors BCLC B2 substage (single or multiple beyond up-to-7 rule), unilobar segmental lobar portal vein invasion (PVI); no extrahepatic...
This paper encompasses classic trends as well recent advances in the understanding of emulsion inversion phenomena. The generalized formulation issue is first discussed from hydrophilic−lipophilic balance to most concepts. so-called standard line on formulation−composition map exhibits several branches, referred transitional and catastrophic inversions, that bound normal abnormal regions. Dynamic also with its hysteresis zones, where both types emulsions may be attained, depending upon...
Fetal exposure to maternal glucocorticoids may determine fetal growth and the programing of later disorders. Availability in placenta is regulated by 11beta-hydroxysteroid dehydrogenase (11beta-HSDs) enzymes. To date, there are discrepancies with regard cortisol (F) cord blood levels fetuses intrauterine retardation different species. Objective study expression activity 11beta-HSDs placentas from full term small for gestational age (SGA), appropriate (AGA) large (LGA) newborns,...
Abstract Surfactant–oil–water systems exhibit a low interfacial tension minimum when the interactions between adsorbed surfactant with water exactly coincide its oil. This occurrence takes place at so‐called optimum formulation, which was conceptually derived by Winsor in 1950s and rendered numerical correlations for enhanced oil recovery 1970s. The actual value of has been found to increase or decrease formulation variables though some hints are available, no general relationship reported...
The rate of addition the internal phase influences catastrophic inversion emulsions in direction change from abnormal to normal morphology. At a low rate, takes place after small amount is added, and it happens through occurrence multiple emulsion high appears be delayed, without emulsion.
The stirring intensity has a complex effect on the catastrophic inversion of emulsions in direction change from abnormal to normal morphology. At both low and high energy, takes place early, after amount internal phase is added through occurrence multiple emulsion. some intermediate appears be delayed it without emulsions.
The catastrophic emulsion inversion from abnormal to normal morphology is produced in different conditions, as far the experimental protocol concerned. Far optimum formulation, found take place when fraction of dispersed phase, which may be a single phase or an inner multiple emulsion, reaches critical packing value. Near so-called low-tension streaming-bicontinuity regime happen instead morphology. phenomenology used interpret emulsification viscous oil phases industrial processes.
When the emulsion inversion from an abnormal oil-in-water (O/W) system to a normal water-in-oil (W/O) morphology is produced by continuous stirring, fraction of dispersed phase at which triggered (which known as critical fraction) and mechanism are affected change in viscosity. As viscosity any phases increases, decreases. oil has similar or higher than water phase, occurs via formation multiple w/O/W, "W" external continuously included "w" droplets "O" drops. Hence, apparent volume...
Hepatitis C virus (HCV) infection is associated with neuropsychiatric disturbances that impact on functioning and health-related quality of life (HRQoL). Reversibility at different liver disease stages unknown, particularly in cirrhosis. We aimed to evaluate cognition, functioning, HRQoL following HCV eradication stages.A random sample (n = 152) consecutive patients treated direct-acting antiviral agents (DAAs) between April 2015 March 2017 were included. A comprehensive neuropsychological...
To describe the results of home enteral nutrition (HEN) registry NADYA-SENPE group in 2010.We retrieved data patients recorded from January 1st to December 31st registered 6,591 (51% males) with 6,688 episodes HEN, 32 hospitals. Mean age those younger than 14 yr (4%) was 1 ± 2 yrs (m SD) and 69,9 17,8 older yr. The length HEN longer 76% patients. most frequent underlying disease neurological disorders 42%, followed by cancer 28% (mostly head neck 18%). We had information related access route...
Abstract All variables capable of altering the physico‐chemical formulation, including temperature, are included in a generalized concept known as hydrophilic–lipophilic deviation (HLD), which measures departure from reference state at surfactant–oil–water system exhibits Winsor III three‐phase behaviour. The general phenomenology representing emulsion properties (type, stability, viscosity, drop size) can be qualitatively charted three‐dimensional map, where each region definite features....
Abstract Emulsion inversion produced by a change in temperature usually takes place reversibly, ie at the same whatever direction of change. The present study indicates previously unreported hysteresis transitional driven variation non‐ionic system containing Tween surfactant mixtures. In both directions variation, delay is exhibited with respect to standard phase equilibrated system. width region depends on rate This behaviour, which does not happen presence alcohol, attributed liquid...
Recent data have suggested a faster deterioration of multiple sclerosis (MS) patients who harbour the epsilon4 allele apolipoprotein E (APOE) gene. We investigate relationship APOE genotypes with disease severity and clinical recovery relapses in MS population north Spain.One hundred thirty-three clinically defined were studied. Disease course (relapsing versus progressive), age onset, duration disability measured by Expanded Disability Status Scale (EDSS) recorded. Worsening was Progression...