A5102963224- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Eosinophilic Esophagitis
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Asthma and respiratory diseases
- Infant Development and Preterm Care
- Photosynthetic Processes and Mechanisms
- Infant Nutrition and Health
- Pediatric health and respiratory diseases
- Central Venous Catheters and Hemodialysis
- COVID-19 and healthcare impacts
- Ophthalmology and Eye Disorders
- Plant Molecular Biology Research
- Urticaria and Related Conditions
- Epigenetics and DNA Methylation
- Rheumatoid Arthritis Research and Therapies
- HER2/EGFR in Cancer Research
- Analytical Methods in Pharmaceuticals
- Neonatal and fetal brain pathology
- Osteomyelitis and Bone Disorders Research
- Salivary Gland Disorders and Functions
- Reproductive tract infections research
- Gastrointestinal disorders and treatments
- Mast cells and histamine
First Affiliated Hospital of Zhengzhou University
2014-2024
Wuhan University
2022-2024
University of North Carolina at Chapel Hill
2015-2023
Beijing Chaoyang Emergency Medical Center
2022
China Pharmaceutical University
2016
Boston Children's Hospital
2015
Central Hospital Affiliated to Shenyang Medical College
2012
Duke Medical Center
2010-2011
China Medical University
2003-2010
Zhengzhou Children's Hospital
2007
BackgroundPrior studies of peanut sublingual immunotherapy (SLIT) have suggested a potential advantage with younger age at treatment initiation.ObjectiveWe studied the safety and efficacy SLIT for allergy in 1- to 4-year-old children.MethodsPeanut-allergic children were randomized receive 4 mg versus placebo. Desensitization was assessed by double-blind, placebo-controlled food challenge (DBPCFC) after 36 months treatment. Participants desensitized least 443 protein discontinued therapy 3...
Abstract Background Prolonged exposure to hyperoxia in neonates can cause hyperoxic acute lung injury (HALI), which is characterized by increased pulmonary permeability and diffuse infiltration of various inflammatory cells. Disruption the epithelial barrier may lead altered maintenance properties requires intact tight junctions (TJs). However, neonatal animals, relatively little known about how TJ proteins are expressed epithelium, including whether expression regulated response exposure....
Mechanisms underlying oral immunotherapy (OIT) are unclear and the effects on immune cells at varying maintenance doses unknown.We aimed to determine immunologic changes caused by peanut OIT in preschool aged children effect these responses groups ingesting low or high-dose (300 mg 3000 mg, respectively) as therapy.Blood was drawn several time-points throughout protocol PBMCs isolated cultured with antigens. Secreted cytokines were quantified via multiplex assay, whereas Treg...
The rapid spread of COVID-19 has overwhelmed healthcare systems across the world. During early stage pandemic, frontline workers (FHWs) caring for patients at intensive care units (ICUs) faced extreme pressure and challenges. This qualitative study aimed to describe different phases psychological distress FHWs during pandemic.Qualitative study.The First Affiliated Hospital Zhengzhou University, a designated hospital with in central China.Eight physicians six nurses working ICU who provided...
Abstract The maintenance of a proton gradient across the thylakoid membrane is an integral aspect photosynthesis that mainly established by splitting water molecules in photosystem II and plastoquinol oxidation at cytochrome complex, it necessary for generation ATP last step photophosphorylation. Although environmental stresses, such as high temperatures, are known to disrupt this fundamental process, only few studies have explored molecular mechanisms underlying regulation during stress....
A sensitive and rapid ultra-performance liquid chromatography tandem mass spectrometry (UPLC–MS-MS) method was developed to determine sertraline in human plasma. Sample preparation accomplished through a simple liquid–liquid extraction with ethyl acetate. Chromatographic separation carried out on an Acquity UPLC BEH C18 column using gradient mobile phase system composed of acetonitrile 1% formic acid water at flow rate 0.40 mL/min. Mass spectrometric analysis performed XEVO TQD spectrometer...
Abstract Background: The aim of the present study was to investigate p16 promoter methylation in premature rats with chronic lung disease (CLD) induced by hyperoxia. Methods: Eighty Wistar were randomized into hyperoxia group (fraction inspired oxygen [FiO 2 ]= 900 mL/L) or control (FiO = 210 mL/L), 40 for each group. Semi‐nested methylation‐specific polymerase chain reaction (sn‐MSP) applied detect hypermethylation tissues. Additionally, mRNA and protein expression detected on reverse...
Objective. To evaluate the effect of hemp cotton sanitary pads on vaginal microecology. Methods. A randomized controlled field trial was used to recruit 1002 community-based women childbearing age. The were randomly divided into experimental and control groups. group pads, while two types chosen from top five in terms market share China. microecology compared between groups after three months. Results. According microecologic examination results at baseline, included 3 groups: normal...
To evaluate the effects of multiple single cannulation technique (MUST) on outcomes arteriovenous graft (AVG).
Abstract Venation develops complex patterns within the leaves of angiosperms, and mechanism leaf vein patterning remains poorly understood. Here, we report a spontaneous mutant that exhibits yellow serrated defective cotyledon patterning. We mapped cloned relevant gene YELLOW, SERRATED LEAF (YSL), previously unreported in plants. YSL interacts with VH1-interacting kinase (VIK), protein functions venation development. VIK is vascular-specific adaptor another vascular developmental protein,...
Objective To investigate the surgical approach for angle-closure glaucoma combined with cataract.Methods Totally 124 eyes of 116 patients cataract were divided into two groups according to their intraocular pressure(IOP) and degrees synechial angle closure(SAC).Group A:76 SAC ≤ 180° IOP 30 mmHg (1 =0.133 kPa) after control pilocarpine treated phacoemulsification lens (IOL) implantation goniosynechialysis.Group B:48 ＞ 30mmHg IOL trabeculectomy.The follow-up time was 6 months.The vision,IOP...
Objective To investigate the clinical characteristics and summarize experiences on diagnosis treatment of gastritis cystica profunda (GCP).Methods Clinical data 15 GCP patients,who were treated in First Second Affiliated Hospital Zhengzhou University from January 2006 to 2013,were retrospectively analyzed.Results may present clinically as abdominal pain,bloating,emaciation,and GI bleeding.CT,electronic gastroscope,or ultrasonic endoscope shows that consists multiple cysts within a thickened...