Santiago Salazar

ORCID: 0000-0003-2614-1218
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About
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Research Areas
  • Cephalopods and Marine Biology
  • Marine animal studies overview
  • Nutrition and Health in Aging
  • Aortic Disease and Treatment Approaches
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cardiac Valve Diseases and Treatments
  • Restraint-Related Deaths
  • Cardiac Structural Anomalies and Repair
  • High Altitude and Hypoxia
  • Respiratory Support and Mechanisms
  • Infective Endocarditis Diagnosis and Management
  • Veterinary medicine and infectious diseases
  • Foreign Body Medical Cases
  • Abdominal Surgery and Complications
  • Human-Animal Interaction Studies
  • Limits and Structures in Graph Theory
  • RNA modifications and cancer
  • Point processes and geometric inequalities
  • Vector-Borne Animal Diseases
  • Tribology and Lubrication Engineering
  • Mechanical Failure Analysis and Simulation
  • Bioactive Compounds and Antitumor Agents
  • Aortic aneurysm repair treatments
  • Abdominal Trauma and Injuries
  • COVID-19 and Mental Health

Universidad Nacional de Colombia
2015-2025

University of Concepción
2023-2024

Escuela Politécnica del Ejército
2021

Clínica Santa María
2021

Hospital Vozandes
2019-2020

University of Calgary
2015-2018

Hospital Universitario Nacional de Colombia
2015

Charles Darwin Foundation
2003-2008

Universidad Autónoma de Baja California Sur
2008

Instituto Politécnico Nacional
2008

Introduction Pancreatic and periampullary adenocarcinomas are associated with abnormal body composition visible on CT scans, including low muscle mass (sarcopenia) radiodensity due to fat infiltration in (myosteatosis). The biological clinical correlates these features poorly understood. Methods Clinical characteristics outcomes were studied 123 patients who underwent pancreaticoduodenectomy for pancreatic or non-pancreatic adenocarcinoma had available preoperative scans. In a subgroup of...

10.1371/journal.pone.0196235 article EN cc-by PLoS ONE 2018-05-03

MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 363:299-309 (2008) - DOI: https://doi.org/10.3354/meps07457 Multiple foraging strategies in a marine apex predator, Galapagos sea lion Zalophus wollebaeki Stella Villegas-Amtmann1,*, Daniel P. Costa1, Yann Tremblay1, Sandie Salazar2,3, David Aurioles-Gamboa2 1Department of and Evolutionary Biology, Long...

10.3354/meps07457 article EN Marine Ecology Progress Series 2008-07-15

Summary The movement of materials and organisms between ecosystems is a common process in nature. In the present study we investigate hypothesis that transport nutrients by low‐mobility species their effect on terrestrial depends habitat topography. Specifically, hypothesized influence marine organism with low mobility environments would be spatially restricted. To address this analysed distribution (both geographical local scales) Galapagos sea lion colonies, quantified spatial extent (soil...

10.1046/j.1365-2656.2003.00760.x article EN Journal of Animal Ecology 2003-08-15

Foreign body (FB) ingestion and aspiration are frequent causes of pediatric emergency room visits, with significant morbidity mortality risks. This cross-sectional study analyzed 1,052 patients admitted for suspected FB events at a single institution between 2008 2015, including 886 cases 166 aspiration. Cluster analysis identified three distinct clusters both groups, respiratory symptoms being predominant in worse outcomes. The were associated increased complication rates (13.0% aspiration,...

10.1038/s41598-024-84042-7 article EN cc-by-nc-nd Scientific Reports 2025-01-02

NK-lysin is a potent antimicrobial peptide (AMP) with activity against bacteria, fungi, viruses, and parasites. type of granulysin, member the saposin-like proteins family first isolated from pig’s small intestine. In previous work, for time, we identified four variants nk-lysin Atlantic salmon ( Salmo salar ) using EST sequences. present study, reported characterized two additional transcripts S. . Besides, evaluated tissue distribution three NK-lysins assessed antimicrobial, hemolytic,...

10.3389/fimmu.2024.1191966 article EN cc-by Frontiers in Immunology 2024-04-09

Three species of otariids are found in the coastal zone and marine area Ecuador Galapagos Islands. Two species, sea lion (Zalophus wollebaeki ) fur seal (Arctocephalus galapagoensis), endemic to Galapagos. The South American (Otaria flavescens has been recorded several times on Ecuadorian coast, even small semi-permanent or resident male groups (~10-30 animals) have frequently observed two southern locations (Santa Clara Island Punta Brava-Salinas). most recent estimates populations,...

10.4027/slw.2006.31 article EN 2006-05-01

Multivalent live-attenuated or inactivated vaccines are often used to control the bovine viral diarrhea disease (BVD). Still, they retain inherent disadvantages and do not provide expected protection. This study developed a new vaccine prototype, including external segment of E2 protein from five different subgenotypes selected after massive screening. The proteins every subgenotype (1aE2, 1bE2, 1cE2, 1dE2, 1eE2) were produced in mammalian cells purified by IMAC. An equimolar mixture...

10.3390/ijms25168734 article EN International Journal of Molecular Sciences 2024-08-10

Three fundamental foraging patterns in air-breathing marine vertebrates have been described: epipelagic, mesopelagic and benthic. Many sea lion species with access to extensive continental shelves described as benthic foragers. Coincidently these are considered threatened. The Galapagos Zalophus wollebaeki, a top predator the Islands, is also threatened this ecosystem. Sea lions at central part of archipelago vast shelf. For reason we hypothesized that within region would dive benthically....

10.3354/mepsm7457 article EN Marine Ecology Progress Series 2008-01-01

Previously, we designed a subunit vaccine candidate based on three L. intracellularis antigens with promising results in pigs. In this study, were produced individually to achieve an even antigen ratio the formulation. The emulsion characterization included drop size and mechanical thermal stability. Immune response was evaluated by indirect sandwich ELISAs, qPCR, flow cytometry. candidate's safety assessed histopathology monitoring clinical behavior of animals. average production yielded...

10.3390/vaccines11121817 article EN cc-by Vaccines 2023-12-04

The COVID-19 pandemic, caused by the SARS-COV-2 virus, has had devastating consequences worldwide. Remarkably, incidence, virus transmission capacity, and severity of have been reported to be significantly decreased in high-altitude human populations. clinical significance these findings is enormous, as they suggest that permanent inhabitants high altitudes developed adaptive protective changes against certain pathologies. However, observations overshadowed contradictory reports on mortality...

10.18103/mra.v11i8.4299 article EN Medical Research Archives 2023-01-01

<title>Abstract</title> Foreign body (FB) events are prevalent in emergency room consultations, with 107,000 cases annually the United States (80% pediatric population). They result an estimated 1,500 mortalities each year. A cross-sectional study between February 2008 and September 2015, employing hierarchical cluster analysis of signs symptoms at presentation to was performed. Sensitivity, specificity, decision curve for a caregivers’ report calculated confirmed FB diagnosis as reference....

10.21203/rs.3.rs-4831473/v1 preprint EN cc-by Research Square (Research Square) 2024-10-07

A \emph{simple} matrix is a (0,1)-matrix with no repeated columns. For $F$, we say that $A$ has $F$ as \emph{Berge hypergraph} if there submatrix $B$ of and some row column permutation $G$, $G\le B$. Letting $||A||$ denote the number columns in $A$, define extremal function $Bh(m,{ F})=\max\{||A||\,:\, \hbox{ }m\hbox{-rowed simple Berge hypergraph }F\}$. We determine asymptotics $Bh(m,F)$ for all $3$- $4$-rowed most $5$-rowed $F$. certain this becomes problem determining maximum copies $K_r$...

10.48550/arxiv.1608.03632 preprint EN other-oa arXiv (Cornell University) 2016-01-01

Lawsonia intracellularis remains a problem for the swine industry worldwide. Previously, we designed and obtained vaccine candidate against this pathogen based on chimeric proteins: OMP1c, OMP2c, INVASc. These proteins formed inclusion bodies when expressed in E. coli, which induced humoral cellular immune responses vaccinated pigs. Also, protection was demonstrated after challenge. In study, established production process to increase yields of three antigens as candidate. Batch fed-batch...

10.1016/j.ejbt.2021.01.002 article EN cc-by-nc-nd Electronic Journal of Biotechnology 2021-01-19

Se describe el caso de un paciente sexo masculino, 43 años edad, con diagnóstico infección por virus la inmunodeficiencia humana y síndrome adquirida, no usuario drogas intravenosas, quien presentó imágenes pulmonares cavitadas compatibles embolia séptica en contexto endocarditis infecciosa válvula pulmonar bacteriemia Pseudomonas aeruginosa, respuestas clínica ecocardiográfica favorables al manejo antibioticoterapia. La derecha es responsable 5 a 10% todos los casos endocarditis. Aunque...

10.30789/rcneumologia.v26.n3.2014.40 article ES Revista Colombiana de Neumología 2014-07-20

e15289 Background: Cachexia is a common manifestation of pancreatic cancer and other periampullary adenocarcinomas. Sarcopenia (low muscle mass) one cachexia. Reduced skeletal attenuation on CT scan also often accompanies cachexia, this thought to be related fat infiltration (myosteatosis). We postulated that changes in body composition signify cachexia adversely affect perioperative outcomes survival. Methods: 123 patients who underwent Whipple pancreaticoduodenectomy for adenocarcinoma or...

10.1200/jco.2015.33.15_suppl.e15289 article EN Journal of Clinical Oncology 2015-05-20

# Real-time electromagnetic navigation in breast-conserving surgery: clinical feasibility study on palpable tumours {#article-title-2} Breast cancer is treated its early stages with surgery. Current strategies still lead to a re-excision rate for positive margins as high 47

10.1503/cjs.007116 article EN Canadian Journal of Surgery 2016-06-01
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