A5034048815- Intraperitoneal and Appendiceal Malignancies
- Ovarian cancer diagnosis and treatment
- Appendicitis Diagnosis and Management
- Porphyrin Metabolism and Disorders
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Metabolism and Genetic Disorders
- Esophageal and GI Pathology
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Tumor Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Adrenal and Paraganglionic Tumors
- Gallbladder and Bile Duct Disorders
- Glaucoma and retinal disorders
- Renal cell carcinoma treatment
- Hernia repair and management
- Folate and B Vitamins Research
- Ocular Surface and Contact Lens
- Neuroendocrine Tumor Research Advances
- Multiple and Secondary Primary Cancers
- Endometriosis Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Metastasis and carcinoma case studies
- Congenital Anomalies and Fetal Surgery
University of Messina
2015-2024
Martin University
2024
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2017-2023
Istituto Ortopedico Gaetano Pini
2021
San Gallicano Hospital
1988-2019
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2019
Aerospace Center Hospital
2018
ASL Roma
2018
University of Turin
2014
National Cancer Institute
2013
The aim of this study was to help with the process selecting patients advanced ovarian cancer undergo cytoreductive surgery (CRS) hyperthermic intraperitoneal chemotherapy (HIPEC) by analyzing outcome data at distinct clinical time points reflecting natural history disease.In a retrospective Italian multicenter investigating who underwent CRS plus HIPEC between 1998 and 2014, we analyzed for consecutive eight treatment points: primary debulking (PDS); interval after partial response, no...
Please cite this paper as: Deraco M, Virzì S, Raspagliesi F, Iusco D, Puccio Macrì A, Famulari C, Solazzo Bonomi Grassi Baratti Kusamura S. Secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer: a multi‐institutional study. BJOG 2012;119:800–809. Objective To assess the efficacy morbidity mortality of (CRS) (HIPEC) in cancer (EOC). Design A retrospective study conducted using information extracted from prospective database on...
•The prognostic value of specific KRAS mutations in patients with isolated CRC PM is unclear.•KRAS mutation subgroups can be determined according to codon substitution.•KRASMUT1 group has similar prognosis wild-type patients.•KRASMUT2 associated poorer than KRASMUT1 and KRASWT.•KRASMUT2 occur the P-loop region, decreased GTP hydrolysis, change polarity size AA. BackgroundThere little evidence on mutational profiles colorectal cancer (CRC) peritoneal metastases (PM). This study aims determine...
The development of multimodality treatment, including cytoreductive surgery (CRS) with heated intraperitoneal chemotherapy (HIPEC), has led to promising results in selected patients peritoneal disease gastric origin. aim this study was investigate the short- and long-term outcomes CRS/HIPEC treatment synchronous metastasis cancer.The Italian Peritoneal Surface Malignancies Oncoteam-S.I.C.O. retrospective registry included malignancy from cancer submitted gastrectomy CRS HIPEC between 2005...
Spices and aromatic herbs have always had great historical importance in human nutrition. Their use has been documented for centuries as a rich source of bioactive compounds; they used their health benefits also flavoring or coloring food. However, despite the many properties linked to spices herbs, these can represent biological hazards contain chemical substances concern. Certainly, monitoring potential includes microbiological safety content inorganic substances: both key step. This...
Peritoneal carcinomatosis is the most frequent site of metastases in patients with gastric cancer. Current standard treatment palliative systemic chemotherapy very poor prognosis. Cytoreductive surgery (CRS) combined hyperthermic intraperitoneal (HIPEC) resulted long-term benefits selected patients. Among peritoneal carcinomatosis, a distinctive subset oligometastatic disease which characterized by low metastatic burden. Pressurized aerosol (PIPAC) recent technique used combination promising...
The reiteration of surgical cytoreduction (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients affected by recurrent peritoneal metastases is still questioned regarding safety effectiveness. This study evaluates the safety, efficacy, associated factors iterative CRS combined with HIPEC. multicentric retrospective collected data from four oncology centers, on We gathered patient cancer characteristics, index (PCI), completeness (CC), postoperative complications, overall...
Despite the efforts made, a serum marker reliable for screening and follow-up of patients with gastric cancer has not yet been identified. The aim this preliminary study was to test role pro-inflammatory cytokines interleukin 1beta, 8 tumour necrosis factor alpha in control groups. statistical analysis levels group versus groups shown considerable differences (p < 0.001) their mean rates. results indicate that might perhaps act as diagnostic markers cancer. Therefore, it is hypothesized...
Activation of the adenosine receptor pathway has been demonstrated to be effective in improving tissue remodeling and blunting inflammatory response. Active colitis is characterized by an intense reaction resulting extensive damage. Symptomatic improvement requires both control process repair damaged tissues. We investigated ability A2A agonist, polydeoxyribonucleotide (PDRN), restore structural integrity two experimental models using male Sprague-Dawley rats. In first model, was induced...
Abstract The recent outbreak of COVID-19 in Italy caused a limitation the resources health system, which necessarily led to their rationalization critical phase (phase 1) and reorganization system following 2). Italian Society Oncological Surgery–SICO has drafted these practical recommendations, calibrated on most scientific literature taking into account current regulations common sense. Surgical activity during 1 2 should follow dynamic model, considering architectural structures, hospital...
Retroperitoneal soft-tissue sarcomas are relatively uncommon diseases, the most frequent histotype, ranging from 20% to 45% of all cases, is represented by liposarcoma, which a hard-to treat condition for its local aggressiveness and clinical aspecificity.We report case 64-years-old woman who underwent surgical resection giant pleomorphic retroperitoneal liposarcoma.Currently chemotherapy no effective, radiotherapy has limited efficacy due toxicity affecting adjacent intra-abdominal...