A5069146280- Advanced Radiotherapy Techniques
- Labor Movements and Unions
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Cardiac Arrhythmias and Treatments
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Social Policy and Reform Studies
- Advances in Oncology and Radiotherapy
- Cardiac pacing and defibrillation studies
- Advanced X-ray and CT Imaging
- Orbital Angular Momentum in Optics
- Quantum Information and Cryptography
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Radiation Dose and Imaging
- Management of metastatic bone disease
- Quantum optics and atomic interactions
- Organ Transplantation Techniques and Outcomes
- Effects of Radiation Exposure
- Laser-Matter Interactions and Applications
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Renal Transplantation Outcomes and Treatments
Vrije Universiteit Amsterdam
1984-2025
Amsterdam University Medical Centers
2018-2025
University of Arusha
2025
University of Amsterdam
2003-2024
Cancer Center Amsterdam
2023-2024
Amsterdam UMC Location University of Amsterdam
2014-2022
Sheba Medical Center
2018
Radboud University Nijmegen
2012
Leiden University
2002-2006
Huygens Institute for History and Culture of the Netherlands
2002-2005
Online adaptive radiotherapy has the potential to reduce toxicity for patients treated rectal cancer because smaller planning target volumes (PTV) margins around entire clinical volume (CTV) are required. The aim of this study is describe first experience a Conebeam CT (CBCT)-based online workflow cancer, evaluating timing different steps in workflow, plan quality, coverage and patient compliance.Twelve consecutive eligible 5 × Gy pre-operative were on ring-based linear accelerator with...
Standard palliative radiotherapy workflows involve waiting times or multiple clinic visits. We developed and implemented a rapid workflow using diagnostic imaging (dCT) for pre-planning, with subsequent on-couch target plan adaptation based on synthetic computed tomography (CT) obtained from cone-beam CT (CBCT).Patients painful bone metastases recent were eligible inclusion in this prospective, ethics-approved study. The consisted of 1) telephone consultation radiation oncologist (RO); 2)...
Abstract Aims Stereotactic arrhythmia radiotherapy (STAR) is suggested as potentially effective and safe treatment for patients with therapy-refractory ventricular tachycardia (VT). However, the current prospective knowledge base experience STAR limited. In this study we aimed to prospectively evaluate efficacy safety of STAR. Methods results The StereoTactic Arrhythmia Radiotherapy in Netherlands no.1 was a pre-post intervention VT, pro-arrhythmic region treated 25 Gy single fraction. main...
Conventional techniques (3D-CRT) for craniospinal irradiation (CSI) are still widely used. Modern (IMRT, VMAT, TomoTherapy®, proton pencil beam scanning [PBS]) applied in a limited number of centers. For 14-year-old patient, we aimed to compare dose distributions five CSI across Europe and generated according the participating institute protocols, therefore representing daily practice.A multicenter (n = 15) dosimetric analysis different (3D-CRT, IMRT, PBS; 3 centers per technique) was...
Cardiac radioablation has evolved as a potential treatment modality for therapy-refractory ventricular tachycardia. To standardize cardiac treatments, promote accurate communication and target identification, to assess toxicity, robust, reproducible methods angulation segmentation are paramount. In this study, we developed evaluated tool semiautomated according the American Heart Association 17-segment model.
To investigate the role of nitric oxide (NO) in bacterial meningitis, concentrations serum, cerebrospinal fluid (CSF), or both precursor (l-arginine) and degradation products NO (nitrate, nitrite) tumor necrosis factor (TNF)-α were measured 35 patients 30 controls. CSF nitrate levels significantly elevated, mainly due to increased blood-brain barrier permeability, are therefore not a good parameter for gauging endogenous production compartment. NO/nitrite elevated patients. decreased over...
Radiation therapy (RT) using a daily plan selection adaptive strategy can be applied to account for interfraction organ motion while limiting at risk dose. The aim of this study was quantify the dosimetric consequences compared with non-adaptive RT in cervical cancer.Ten consecutive patients who received pelvic irradiation, planning CTs (full and empty bladder), weekly post-fraction pre-fraction CBCTs were included. Non-adaptive plans generated based on PTV defined full bladder CT. For...
The aim was to assess the feasibility of online adaptive radiotherapy (oART) for bladder cancer using a focal boost by focusing on quality treatment plan and automatic target delineation, duration workflow performance in presence fiducial markers tumor bed localization.Fifteen patients with muscle invasive received daily oART Cone Beam CT (CBCT), artificial intelligence (AI)-assisted delineation anatomy reoptimization. pelvic lymph nodes total dose 40 Gy 20 fractions, an additional...
ABSTRACT Water operator partnerships (WOPs) have gained significant traction since their initiation in 2006. Although a large variety of WOPs is operational around the world, each having different approach and organizational structure, there limited knowledge about factors that determine effectiveness success WOPs. This article shares Tanzanian to WOPs, which can be considered as triangular WOP with multiple local water sanitation authorities, single lead partner. The based on two building...
Summary. A prospective study was carried out to determine whether use of cytomegalovirus (CMV) unscreened red blood cells and platelet concentrates, white cell (WBC) depleted with high‐efficiency filters, would prevent transfusion‐associated (TA) CMV infection in seronegative bone marrow transplant recipients. Blood components were filtered the bloodcentre under quality control after filtration residual WBC counts always below 5 × 10 6 cells/U. Since 1990, 23 consecutive allogeneic 37...
To compare online adaptive radiation therapy (ART) to a clinically implemented plan selection strategy (PS) with respect dose the organs at risk (OAR) for rectal cancer.The first 20 patients treated PS between May-September 2016 were included. This resulted in 10 short (SCRT) and long (LCRT) course radiotherapy treatment schedules total of 300 Conebeam CT scans (CBCT). New dual arc VMAT plans generated using auto-planning both ART strategy. For each fraction bowel bag, bladder mesorectum...
In patients with recurrent ventricular tachycardia (VT), STereotactic Arrhythmia Radioablation (STAR) shows promising results. The STOPSTORM.eu consortium was established to investigate and harmonise STAR treatment in Europe. primary goals of this benchmark study were standardise contouring organs at risk (OAR) for STAR, including detailed substructures the heart, accredit each participating centre.Centres within asked delineate 31 OAR three cases. Delineation reviewed by expert panel after...
The role of NO during the first hour endotoxemia is still controversial. To evaluate whether protective or detrimental to regulation systemic blood pressure, cardiac output (CO), and organ perfusion in rats acute endotoxemia, we have studied effects inhibition synthesis. Thirty minutes after 0.1 mg NG-nitro-L-arginine (L-NNA; group L, n = 7, partial inhibition), 1 L-NNA (group H, 6, complete saline E, 7) intravenous infusion, anesthetized volume-loaded were infused with endotoxin Escherichia...
Poor early graft function (EGF) after living donor kidney transplantation (LDKT) has been found to decrease rejection-free survival rates. However, its influence on long-term remains inconclusive.Data were collected 472 adult LDKTs performed between July 1996 and February 2010. EGF was defined as the occurrence of delayed or slow function. Slow serum creatinine above 3.0 mg/dL at postoperative day 5 without dialysis.The incidence 9.3 4.4%, respectively. Recipient overweight, pretransplant...