Helen Karimi

ORCID: 0000-0003-2780-7114
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Spinal Fractures and Fixation Techniques
  • Nausea and vomiting management
  • Scoliosis diagnosis and treatment
  • Spinal Cord Injury Research
  • Invertebrate Immune Response Mechanisms
  • Neurobiology and Insect Physiology Research
  • Spinal Dysraphism and Malformations
  • Musculoskeletal pain and rehabilitation
  • Management of metastatic bone disease
  • Infectious Diseases and Tuberculosis
  • Pelvic and Acetabular Injuries
  • Hip and Femur Fractures
  • Insect symbiosis and bacterial influences
  • Cervical and Thoracic Myelopathy
  • Insect Utilization and Effects
  • Opioid Use Disorder Treatment
  • Intensive Care Unit Cognitive Disorders
  • Nerve Injury and Rehabilitation
  • Medical Malpractice and Liability Issues
  • Cerebrospinal fluid and hydrocephalus
  • Pain Management and Opioid Use

Tufts University
2023-2025

Tufts Medical Center
2023-2025

Brown University
2024

Rhode Island Hospital
2024

Wesleyan University
2021

Spine surgery is highly litigious; misplaced screws and intraoperative neuromonitoring frequently feature in lawsuits. Intraoperative aims to prevent injury but its standards are debated, literature suggests benefits mixed. We surveyed use among neurosurgeons from the Congress of Neurological Surgeons with Pearson's chi-square test applied analyse data within R. Among 188 respondents, 39.9% worked private practice or academic institutions. Usage rates were 50.5% always, 27.7% never 21.8%...

10.1177/00258172241279618 article EN Medico-Legal Journal 2025-01-17

Despite recent evidence demonstrating its safety and efficacy, spinal anesthesia remains a seldom-utilized anesthetic modality in lumbar surgical procedures. In addition, numerous clinical advantages, such as reduced cost, blood loss, operative time, inpatient length of stay have been consistently demonstrated with over general anesthesia.In this report we aim to examine the differences between regard accessibility climate impact determine whether wider adoption would meaningful on global...

10.1016/j.bas.2023.101754 article EN cc-by-nc-nd Brain and Spine 2023-01-01

This study investigated the prevalence of embryonic and connective tissue elements in filum terminale (FT) patients with tethered cord syndrome (TCS), examining both typical pathological histology. The FT specimens from 288 who underwent spinal detethering 2013 to 2021 were analyzed. histopathological examination involved routine hematoxylin eosin staining specific immunohistochemistry when needed. patient details extracted electronic medical records. found that 97.6% had peripheral nerves,...

10.3390/jcm13010006 article EN Journal of Clinical Medicine 2023-12-19

Abstract Drosophila sechellia is a dietary specialist endemic to the Seychelles islands that has evolved consume fruit of Morinda citrifolia. When ripe, M. citrifolia contains octanoic acid and hexanoic acid, two medium-chain fatty volatiles deter are toxic generalist insects. resistance these allowing it feed almost exclusively on this host plant. The genetic basis been focus multiple recent studies, but mechanisms govern in D. remain unknown. To understand how specialize avoid effects we...

10.1093/g3journal/jkab354 article EN cc-by G3 Genes Genomes Genetics 2021-10-19

BACKGROUND AND OBJECTIVES: Greater thecal sac volumes are associated with an increased risk of spinal anesthesia (SA) failure. The cross-sectional area accurately predicts volume. may be used to adjust the dose and prevent anesthetic We aim assess rate SA failure in a prospective cohort lumbar surgery patients who receive individualized bupivacaine based on preoperative measurement their area. METHODS: A total 80 prospectively received spine under at single academic center (2022-2023)....

10.1227/neu.0000000000002847 article EN Neurosurgery 2024-02-01

INTRODUCTION: Spinal anesthesia (SA) is a safe and effective alternative to general (GA) for lumbar surgery. Widespread adoption of SA has not occurred presumably due surgeons’ concerns difficulties in management patients with comorbidities. Obesity (BMI =30 kg/m2), anxiety, obstructive sleep apnea, re-operation at the same level, multilevel operations have recently been identified as risk factors perioperative complications. METHODS: A retrospective analysis 422 who underwent thoracolumbar...

10.1227/neu.0000000000002809_1069 article EN Neurosurgery 2024-03-15

BACKGROUND Patients with multiple myeloma (MM) are commonly managed by multidisciplinary oncology teams in concordance the neurological, oncological, mechanical, and systematic decision framework. Surgery is indicated for mechanical instability and/or neurological deficits. In neurologically intact mechanically stable patients, chemo- radiotherapy alone often mainstay treatment. OBSERVATIONS A 66-year-old male patient presented a kyphotic chin-on-chest deformity due to undiagnosed spinal MM....

10.3171/case2441 article EN other-oa Journal of Neurosurgery Case Lessons 2024-12-02

Triggered electromyography (tEMG) is an intraoperative neuromonitoring technique used to assess pedicle screw placement during instrumented fusion procedures. Although spinal anesthesia a safe alternative general in patients undergoing lumbar fusion, its use may potentially block conduction of triggered action potentials or require higher threshold currents elicit myotomal responses when using tEMG. Given the broad utilization tEMG for confirmation placement, adoption be hindered by limited...

10.1227/ons.0000000000000640 article EN Operative Neurosurgery 2023-02-03

This study investigated the prevalence of embryonic and connective tissue elements in filum terminale (FT) patients with tethered cord syndrome (TCS), examining both typical pathological histology. FT specimens from 288 who underwent spinal detethering 2013-2021 were analyzed. Histopathological examination involved routine hematoxylin eosin staining specific immunohistochemistry when needed. Patient details extracted electronic medical records. The found that 97.6% had peripheral nerves,...

10.20944/preprints202312.1226.v1 preprint EN 2023-12-18

Abstract Drosophila sechellia is a dietary specialist endemic to the Seychelles islands that has evolved consume fruit of Morinda citrifolia . When ripe, M. contains octanoic acid and hexanoic acid, two medium chain fatty volatiles deter are toxic generalist insects. D. resistance these allowing it feed almost exclusively on this host plant. The genetic basis been focus multiple recent studies, but mechanisms govern in remain unknown. To understand how specialize avoid effects we exposed...

10.1101/2021.06.08.447576 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-06-09
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