A5080611798- Long-Term Effects of COVID-19
- Cardiovascular and exercise physiology
- Diabetes Management and Research
- Heart Rate Variability and Autonomic Control
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet and metabolism studies
- Non-Invasive Vital Sign Monitoring
- COVID-19 and Mental Health
- Cloud Computing and Resource Management
- Pain Management and Placebo Effect
- COVID-19 and healthcare impacts
- Retirement, Disability, and Employment
- Global Cancer Incidence and Screening
- Technology and Data Analysis
- Migraine and Headache Studies
- Surgical site infection prevention
- Restraint-Related Deaths
- Cardiac Imaging and Diagnostics
- Protein Hydrolysis and Bioactive Peptides
- High Altitude and Hypoxia
- Palliative Care and End-of-Life Issues
- COVID-19 Clinical Research Studies
- Colorectal Cancer Surgical Treatments
- Diabetes Treatment and Management
- Neuroinflammation and Neurodegeneration Mechanisms
Keio University Hospital
2022-2025
Keio University Shonan Fujisawa
2025
National Cerebral and Cardiovascular Center
2021
Kitami Institute of Technology
2001
Hiroshima University
1978-1981
Obesity prevalence has increased in Japan recent years. Given the strong association of obesity with poor glycemic control, and risk type 2 diabetes (T2D) central obesity, this study describes current trends relationships between glycated hemoglobin (HbA1c), body mass index (BMI), waist circumference Japanese people T2D. This was a retrospective, cross-sectional T2D who had at least one recorded HbA1c BMI (or circumference) value Medical Data Center Claims database. Five annual cohorts...
Background and Purpose: Although dual antiplatelet therapy (DAPT) with aspirin clopidogrel reduces the recurrence of ischemic stroke while significantly increasing bleeding events compared monotherapy, CSPS.com trial (Cilostazol Stroke Prevention Study combination) showed that DAPT using cilostazol was more effective without risk. In trial, or used as underlying drug. The effectiveness safety each combination were examined clarified. Methods: a multicenter, open-label, randomized controlled...
ABSTRACT Aims/Introduction Obesity is a known risk factor for several chronic diseases, including type 2 diabetes mellitus, which results from increased insulin resistance and impaired secretion. However, the association between obesity in Asian populations has not yet been fully elucidated. Therefore, we aimed to investigate causal relationship body mass index (BMI) glycemic traits using Mendelian randomization (MR). Materials Methods We performed individual‐level MR analyses genetic scores...
A simple method for determining the anaerobic threshold in patients with heart failure (HF) is needed. This prospective clinical trial (LacS-001) aimed to investigate safety of a sweat lactate-monitoring sensor and correlation between lactate (sLT) ventilatory (VT). To this end, we recruited 50 HF New York Heart Association functional classification I–II (mean age: 63.5 years, interquartile range: 58.0–72.0). Incremental exercise tests were conducted while monitoring levels using our sensor....
Due to the coronavirus disease 2019 (COVID-19) pandemic, cancer screening, diagnosis, and treatment have changed. This study aimed investigate impact of severe acute respiratory syndrome 2 (SARS-CoV-2) infection prior gastroenterological surgeries on postoperative complications using data from a nationwide database in Japan.
Recent data on the prevalence of metabolic syndrome in Japanese patients with type 2 diabetes (T2D) are limited. This retrospective, cross-sectional, observational study investigated T2D using a administrative claims database. Patients diagnosis, prescription hypoglycemic agent, and one or more annual health checkups 2020 were included. Trends by sex body mass index (BMI) subgroup assessed. The cohort consisted 155,653 (men, 81.6%; mean age 54.6 ± 8.5 years). had higher BMI (29.1 4.5 kg/m2...
Maintaining a social environment that enables going out freely is important for older people and aids the prevention of frailty syndrome. However, losing driver’s license can increase long-term care needs people. Therefore, outing support systems are important. utilization rate these currently relatively low. We conducted demonstration experiment among aged 70 years over, living in Iruma City, Saitama Japan, by implementing Choisoko system developed Aisin Co., Ltd., conjunction with an...
Abstract Objective This study aimed to investigate the clinical features of long COVID cases presenting with upper respiratory symptoms, a topic not yet fully elucidated. Study Design Prospective cohort study. Setting A multicenter involving 26 medical facilities in Japan. Methods Inclusion criteria were patients aged ≥18 years old confirmed COVID‐19 diagnosis via severe acute syndrome coronavirus 2 polymerase chain reaction or antigen testing, who hospitalized at participating facilities....
Patients with migraine are typically advised to avoid passive smoking because it may aggravate headaches and other health conditions. However, there is insufficient high-quality evidence on the association between migraine, which warrants further investigation using animal models. Therefore, a mouse model, we examined effect of susceptibility cortical spreading depolarization (CSD), biological basis aura.
Objectives Severe acute respiratory syndrome coronavirus 2 significantly impacts Japan with a high number of infections and deaths reported. Long disease (COVID) characterised by persistent symptoms after COVID-19 has gained recognition but varies across studies. This study aimed to investigate the differences in long COVID among patients hospitalised during Japan’s first three waves pandemic. Design Multicentre prospective cohort study. Setting 26 medical facilities between February 2020...
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly across the globe since 2019, and number of reports regarding long disease 2019 (COVID-19) increased. Although distribution COVID varies according to patient characteristics, including race, epidemiological data on in Japanese patients are limited.Methods: To clarify detailed patients, we performed a multicentre, prospective cohort study, which enrolled hospitalised COVID-19 ≥ 18 years at 26 medical...
Abstract Background The ventilatory threshold (VT), which requires an expensive analyzer and expertise in assessment, has not been widely conveniently used a clinical setting. This prospective trial (LacS-001) aimed to investigate the safety of lactate-monitoring sweat sensor, correlation between lactate (sLT) VT, establish simple method for determining anaerobic patients with heart failure (HF). Methods We recruited 50 HF New York Heart Association functional classification I–II, median age...
<title>Abstract</title> Background A simple method for determining the anaerobic threshold in patients with heart failure (HF) is needed. This prospective clinical trial (LacS-001) investigated safety of a sweat lactate-monitoring sensor and correlation between lactate (sLT) ventilatory (VT). Methods We recruited 50 HF New York Heart Association functional classification I–II (mean age: 63.5 years, interquartile range: 58.0–72.0 years). Incremental exercise tests were conducted while...
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