A5073208510- Sleep and related disorders
- Pharmaceutical Practices and Patient Outcomes
- Metabolomics and Mass Spectrometry Studies
- Health Systems, Economic Evaluations, Quality of Life
- Sleep and Wakefulness Research
- Long-Term Effects of COVID-19
- Workplace Health and Well-being
- Sleep and Work-Related Fatigue
- Nutritional Studies and Diet
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- Balance, Gait, and Falls Prevention
- Schizophrenia research and treatment
- Gut microbiota and health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Health, Environment, Cognitive Aging
- Medication Adherence and Compliance
- COVID-19 and Mental Health
- Circadian rhythm and melatonin
- Thermal Regulation in Medicine
- Pharmaceutical Economics and Policy
- Neurological Disease Mechanisms and Treatments
- Obstructive Sleep Apnea Research
- Noise Effects and Management
- Building Energy and Comfort Optimization
Keio University
2019-2024
Kudanzaka Hospital
2020-2021
Keio University Hospital
2021
General Department of Preventive Medicine
2021
Keio University Shonan Fujisawa
2020
NGK Insulators (Japan)
1995
Introduction: Remote work was widely promoted in 2020, as a result of the COVID-19 pandemic. However, effects remote on psychological and physical stress responses presenteeism workers remain unclear. This research aims to provide empirical evidence implications for people organizations this new scenario working from home. Methods: A two-wave panel survey before after pandemic performed investigate these aspects among office workers. total 3,123 23 tertiary industries responded...
Abstract Background Nosocomial spread of coronavirus disease 2019 (COVID-19) causes clusters infection among high-risk individuals. Controlling this is critical to reducing COVID-19 morbidity and mortality. We describe an outbreak in Keio University Hospital, Japan, its control propose effective measures. Methods When was suspected, immediate isolation thorough polymerase chain reaction (PCR) testing patients health care workers (HCWs) using in-house system, together with extensive contact...
Background: The application of metabolomics-based profiles in environmental epidemiological studies is a promising approach to refine the process health risk assessment. We aimed identify potential urine and plasma for detection relatively low-level cadmium (Cd) exposure large population-based studies.
The aim of this study was to examine the risk falls associated with use non-gamma amino butyric acid (GABA) sleep medications, suvorexant and ramelteon. This case-control case-crossover performed at Kudanzaka Hospital, Chiyoda Ward, Tokyo. A total 325 patients who had 1295 controls matched by sex age were included. inclusion criteria for case group hospitalized their first fall that control did not have a fall, between January 2016 November 2018. internal medications administered classified...
The Tsuruoka Metabolomics Cohort Study (TMCS) is an ongoing population-based cohort study being conducted in the rural area of Yamagata Prefecture, Japan. This aimed to enhance precision prevention multi-factorial, complex diseases, including non-communicable and aging-associated by improving risk stratification prediction measures. At baseline, 11,002 participants aged 35–74 years were recruited City, Japan, between 2012 2015, with follow-up survey. Participants underwent various...
Introduction The rapid spread of COVID-19 posed a global burden. Substantial number people died the disease in acute phase infection. In addition, significant proportion patients have been reported to suffer from post-acute symptoms, sequelae COVID-19, which may negatively influence quality daily living and/or socioeconomic circumstances patients. However, no previous study has comprehensively and objectively assessed life by using existing international scales. Further, evidence...
Abstract Currently, large-scale cohort studies for metabolome analysis have been launched globally. However, only a few evaluated the reliability of urinary analysis. This study aimed to establish metabolomic profiling in studies. In Tsuruoka Metabolomics Cohort Study, 123 charged metabolites were identified and routinely quantified using capillary electrophoresis-mass spectrometry (CE-MS). We approximately 750 quality control (QC) samples 6,720 participants’ spot urine samples. calculated...
Heated tobacco product (HTP) use in Japan has rapidly increased. Despite this rapid spread, little is known about the health effects of HTP use. We conducted a longitudinal cohort study to investigate change smoking habits following spread and its effect on forced expiratory volume 1 second (FEV1) decline.Participants consisted resident population (n = 2,612; mean age, 67.7 years) with FEV1 measurement 2012-2014 2018-2019, worksite 722; age 49.3 without data. Participants were categorized as...
Several studies have suggested the use of psychotropics as a possible risk factor for falling. However, there were several limitations to these previous studies, such data obtained from administrative databases and lack information about time interval between Therefore, in this study, we aimed assess association falling hospitalized patients, using reliable collected medical records.A matched (age, sex, inpatient department) case-control study patients at Tokyo Medical University Hospital...
Excessive daytime sleepiness is increasingly being recognized as a major global health concern. However, there have been few studies related to and its associated factors in elementary school children. In Japan, all schools were closed from February May 2020 prevent coronavirus disease 2019 (COVID-19) outbreaks. The aim of this study was identify changes the subjective pupils during 1.5-year period elucidate with sleepiness. Questionnaire surveys about pupils’ sleep habits Japanese version...
Purpose: Hypertension (HT), dyslipidemia (DL), and diabetes mellitus (DM) are major risk factors for cardiovascular diseases. Despite the wide availability of medications to reduce this risk, poor adherence remains an issue. The aim study is evaluate medication prevalent users in these disease (HT, DL, DM) using claims data. Factors associated with non-adherence were also examined. Methods: Of 7,538 participants Tsuruoka Metabolomics Cohort Study, 3,737（HT: 2,724, DL: 2,137, DM: 665)...
Hypertension (HT), dyslipidemia (DL), and diabetes mellitus (DM) are major risk factors for cardiovascular diseases. Despite the wide availability of medications to reduce this risk, poor adherence remains an issue. The aim study is evaluate medication prevalent users in these disease (HT, DL, DM) using claims data. Factors associated with non-adherence were also examined.
Aim To determine the relationship between multiple medications and falls. Methods This case–control case–crossover study was carried out at Kudanzaka Hospital in Chiyoda, Tokyo, Japan. A total of 325 patients who experienced their first falls when hospitalized January 2016 November 2018, 1285 controls matched by sex, age clinical departments were included this study. Hospitalization duration fall risk score adjusted for analyses. Results In study, multivariable logistic regression showed...
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly across the globe since 2019, and number of reports regarding long disease 2019 (COVID-19) increased. Although distribution COVID varies according to patient characteristics, including race, epidemiological data on in Japanese patients are limited.Methods: To clarify detailed patients, we performed a multicentre, prospective cohort study, which enrolled hospitalised COVID-19 ≥ 18 years at 26 medical...
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL A Population-Based Urinary and Plasma Metabolomics Study of Environmental Exposure Cadmium 33 Pages Posted: 28 Sep 2022 See all articles by Yoshiki IshibashiYoshiki IshibashiKeio University - Department Preventive Medicine Public HealthSei HaradaKeio HealthYoko EitakiKeio HealthAyako KuriharaKeio HealthSuzuka KatoKeio HealthKazuyo KuwabaraKeio...
Aim The risk of falls owing to simultaneous use multiple hypnotics has not been clarified. aim this study was assess the association between 2 and occurrence in hospitalized patients. Methods A matched case-control conducted at Tokyo Medical University Hospital Tokyo, Japan, utilizing data from medical records. Cases were 434 patients who experienced during their hospital stay January 2016 December 2016, controls without falls, individually by age, sex, clinical department. outcome an...
Abstract Currently, large-scale cohort studies for metabolome analysis have been launched globally. However, only a few evaluated the reliability of urinary analysis. This study aimed to establish metabolomic profiling in studies.In Tsuruoka Metabolomics Cohort Study, 123 charged metabolites were identified and routinely quantified using capillary electrophoresis-mass spectrometry (CE-MS). We approximately 750 quality control (QC) samples 6,720 participants’ spot urine samples. calculated...
Abstract Background The purpose of this study was to identify plasma and urinary metabolites that can be used better the effects cadmium exposure than N-acetyl-β-D-glucosaminidase (NAG) using capillary electrophoresis - mass spectrometry (CE-MS). Methods Urinary (U-Cd) measured as an indicator exposure. Fasting urine samples were collected from 1,412 men 2,022 women in Tsuruoka Metabolomics Cohort Study. Charged 94 123 detected determined. Regression analysis performed for NAG, plasma,...