A5039926062- Air Quality and Health Impacts
- Occupational and environmental lung diseases
- Occupational exposure and asthma
- Acute Lymphoblastic Leukemia research
- Multiple Myeloma Research and Treatments
- Workplace Health and Well-being
- Carcinogens and Genotoxicity Assessment
- Estrogen and related hormone effects
- Menopause: Health Impacts and Treatments
- Physical Activity and Health
- Hormonal Regulation and Hypertension
- COVID-19 and healthcare impacts
- Multiple and Secondary Primary Cancers
- Weed Control and Herbicide Applications
- Metabolomics and Mass Spectrometry Studies
- Cancer survivorship and care
- Pesticide and Herbicide Environmental Studies
- Childhood Cancer Survivors' Quality of Life
- Noise Effects and Management
- Advanced Chemical Sensor Technologies
- Radiation Dose and Imaging
- Diet and metabolism studies
- Multiple Sclerosis Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Medical Device Sterilization and Disinfection
University of Cagliari
2014-2024
Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari
2021
Brescia University
2018
University of Brescia
2018
Nuovo Ospedale San Giovanni di Dio
2001
After menopause, both systolic (SBP) and diastolic (DBP) blood pressure (BP) become higher in women than men of the same age, suggesting that estrogen deficiency may influence age-related increase BP. We studied 30 postmenopausal (mean 55 +/- 5.7 years; time from 2-5 years) affected by mild hypertension with no target-organ complications means 24-h BP monitoring. None group were undergoing replacement therapy or taking antihypertensive drugs. According to a randomized, double-blind protocol,...
Breast cancer is one of the most common diseases worldwide, mainly affecting female gender. Considering increase breast incidence and decrease mortality due to news diagnostic therapeutic tools, return work issue after treatment going be very in next years. Occupational physicians therefore need face fitness for workers previously diagnosed with a sufficient cultural technical background. In addition individual characteristics preceding diagnosis, clinical outcome, lifestyles occupational...
Previous research has shown an excess risk of COVID-19 among several occupations, but data on public transport workers are scarce. To investigate the occupational posed by contact with public, we followed up incidence in a cohort workers. We identified incident cases between 1 September 2020 - 6 May 2021 2,052 employees agency Sardinia, Italy. The diagnosis was based positive molecular test. calculate expected events, applied age- and gender-specific rates regional population same time...
: Background: Work-related stress is a potential cardiovascular risk factor, but the underlying mechanism not fully explained. The autonomic nervous system control of cardiac function might play specific role; therefore, monitoring QT interval in electrocardiogram can highlight an imbalance induced by occupational stressors. aim our study was to explore parameters as early indicators relation work-related stress.During 2015-2016 annual workplace health surveillance, we measured 484 workers...
Abstract Background The International Agency for Research on Cancer (IARC) recently classified glyphosate, the most used herbicide worldwide, as a probable human carcinogen. We inquired into association between occupational exposure to glyphosate and risk of lymphoma subtypes in multicenter case-control study conducted Italy. Methods Italian Gene-Environment Interactions Lymphoma Etiology (ItGxE) took place 2011–17 six centres. Overall, 867 incident cases 774 controls participated study....
The occupational exposure to airborne fine and ultrafine particles (UFPs) noise in aircraft personnel employed airport taxiway was investigated. Stationary samplings multiple personal sampling sites job tasks were considered. Size distribution, particle number concentrations, lung dose surface area measured by counters means of an electric low pressure impactor (ELPI+TM). Morphological chemical characterization UFPs performed transmission scanning electron microscopy, the latter together...
(1)H NMR-metabolomic approach was used to investigate QTc interval correlation with plasma metabolic profiles in shiftworkers.Socio-demographic data, electrocardiographic and from 32 male shiftworkers, were correlated by multivariate regression analysis.We found a positive between values, body mass index, glycemia lactate level negative both pyroglutamate 3-hydroxybutyrate level.Our analysis provides evidence of the association clinical, values. This could be identify markers early effects...
Several studies have shown an increased mortality rate for different types of tumors, respiratory disease and cardiovascular morbidity associated with foundry work. Airborne particles were investigated in a steelmaking using electric low-pressure impactor (ELPI+™), Philips Aerasense Nanotracer traditional sampling equipment. Determination metallic elements the collected was carried out by inductively coupled plasma mass spectrometry. The median ultrafine particle (UFP) concentration between...
Background Night shift work can disrupt circadian rhythm and cause chronic sleep deprivation, which might increase the risk of lymphoma through immunosuppression oxidative stress. Material methods We investigated association between night subtypes in 867 incident cases 774 controls, who participated a multicentre Italian study 2011 2017. Based on questionnaire information, occupational experts assessed lifetime probability work, total number shifts years among participants. OR 95% CI for its...
Objectives To explore the time trend and geographical distribution of childhood leukaemia incidence over territory Italian region Sardinia. Setting All hospitals departments, diagnostic centres social security agencies in Sardinia were regularly screened 1974–2003 to identify, register review diagnoses incident cases haematological malignancies (HM). Participants The whole child population aged 0–14 resident Primary secondary outcome measures Incidence HM acute lymphoblastic (ALL) study...
(1) Background: The assessment of airborne particulate matter (PM) and ultrafine particles (UFPs) in battlefield scenarios is a topic particular concern; (2) Methods: Size distribution, concentration, chemical composition UFPs during operative military training activities (target drone launches, ammunition blasting, inert bomb impact) were investigated using an electric low-pressure impactor (ELPI+) scanning electron microscope (SEM), equipped with energy-dispersive spectroscopy (EDS); (3)...
Background: The main anthropic sources of exposure to airborne benzene include vehicular traffic, cigarette smoke, and industrial emissions. Methods: To detect early genotoxic effects environmental benzene, we monitored environmental, personal, indoor in children living an urban area near a petrochemical plant. We also used urinary S-phenylmercapturic acid (S-PMA) as biomarkers 8-hydroxydeoxyguanosine (8-OHdG) biomarker effects. Results: Although always below the European Union limit 5...
A few reports have described increasing trends and spatial distribution of multiple myeloma (MM). We used a validated database including the 1606 cases MM diagnosed in Sardinia 1974-2003 to explore its time trend, we applied Bayesian methods plot probability by administrative unit on regional map. Over 30 years observation, standardized incidence rate (standard world population, all ages) was 2.17 × 10-5 (95% CI 2.01-2.34), 2.29 2.06-2.52) among men, 2.06 1.83-2.28) women. increased...
In both the epidemiological and legal context, causal attribution of asbestos-related lung diseases requires retrospective exposure assessment (REA).To assess correlation between occupational anthropogenic environmental to asbestos its content in tissue.Based on available information, a team physicians retrospectively assessed cumulative 24 subjects who died diseases. The was analysed using analytical scanning electron microscope (SEM-EDS). Log10 fibre count autoptic samples predicted as...
Biomechanical overload due to patients' manual handling represents a relevant contributor chronic low back pain (LBP). Fear of movement (also known as kinesiophobia) and catastrophising may influence the development complaints lower performances also in working environments, despite these issues are poorly investigated.The aim this study is twofold: 1) evaluate levels kinesiophobia catastrophizing sample health personnel with LBP employed activities specifically requiring handling; 2)...
Abstract Background Evidence linking risk of lymphoma and B-cell subtypes to ionizing radiation is inconclusive, particularly at low exposure levels. Methods We investigated (all subtypes), lymphomas, its major subtypes, associated with low-level occupational radiation, in 2346 cases 2463 controls, who participated the multicenter EpiLymph case-control study. developed a job-exposure matrix estimate distinguishing between internal external we applied it lifetime history study subjects,...
Determining the proportion of susceptible workers can represent a first step to biological risk assessment related measles, mumps, rubella and varicella exposure. This study aimed assess immunity against viruses in cohort female school workers.A cross-sectional seroepidemiological sample 263 undergoing routine annual workplace health surveillance program was conducted. As part program, serum samples were collected tested for IgG antibodies.Overall seropositivity 90.5%, 85.2%, 94.7% 97.3%...
Objectives This study aimed to estimate the risk of lymphoma and its major subtypes in relation occupational exposure specific organic dusts. Methods We explored association 1853 cases 1997 controls who participated EpiLymph case–control study, conducted six European countries 1998–2004. Based on expert assessment lifetime exposures, we calculated associated with dusts, namely, flour, hardwood, softwood, natural textile, synthetic leather, two generic (any types) groups: wood textile Risk...
<h3>Objectives</h3> Objective of our pilot study was to explore the airborne ultrafine particle count in residential areas nearby industrial and military settings with reference urban rural areas. <h3>Method</h3> We monitored (ranging 7nm - 10 microm) particles a large oil refinery, shooting range, largest area region area. conducted eight samplings (6 h each) using Electrical low pressure impactor (ELPI plus Dekati, Tampere, FInland). Wind speed direction, temperature humidity during each...