- Obesity, Physical Activity, Diet
- Infection Control and Ventilation
- Body Composition Measurement Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Acute Lymphoblastic Leukemia research
- Childhood Cancer Survivors' Quality of Life
- Inflammatory Bowel Disease
- Birth, Development, and Health
- Climate Change and Health Impacts
- Mobile Health and mHealth Applications
- Adolescent and Pediatric Healthcare
- COVID-19 and healthcare impacts
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Pharmaceutical studies and practices
- SARS-CoV-2 and COVID-19 Research
- Diabetes Management and Research
- COVID-19 epidemiological studies
- Gestational Diabetes Research and Management
- Pituitary Gland Disorders and Treatments
- Physical Activity and Health
- Autoimmune and Inflammatory Disorders
- Simulation-Based Education in Healthcare
- Higher Education Learning Practices
- Opioid Use Disorder Treatment
Hospital for Sick Children
2020-2024
SickKids Foundation
2020-2023
University of Toronto
2021-2023
Cancer Care Ontario
2018-2022
Khon Kaen University
2021
Sault Area Hospital
2021
Western University
2021
Public Health Ontario
2021
Markham Stouffville Hospital
2021
Sunnybrook Health Science Centre
2021
While there is increasing interest in identifying pregnancies at risk for adverse outcome, existing prediction models have not adequately assessed population-based risks, and been based on conventional regression methods. The objective of the current study was to identify predictors fetal growth abnormalities using logistic machine learning methods, compare diagnostic properties a sample infants. Data 30,705 singleton infants born between 2009 2014 mothers resident Nova Scotia, Canada...
Objectives The aim of this study was to quantify the effect COVID-19 pandemic on pediatric emergency department (ED) utilization and outcomes. Methods This is an interrupted-time-series observational children presenting 11 Canadian tertiary-care EDs. Data were grouped into weeks in 3 periods: prepandemic (January 1, 2018–January 27, 2020), peripandemic 28, 2020–March 10, early (March 11, 2020–April 30, 2020). These periods compared with same time intervals 2 preceding calendar years. Primary...
To our knowledge, this is the first pediatric surveillance study of children and adolescents with avoidant restrictive food intake disorder (ARFID).To examine incidence age- sex-specific differences in clinical presentation ARFID Canada.In cross-sectional study, patients were identified through Canadian Paediatric Surveillance Program by surveying 2700 pediatricians monthly from January 1, 2016, to December 31, 2017.The (5-18 years age) characteristics at presentation.In total, 207 (mean...
Background Carbohydrate counting is an important component of diabetes management, but it challenging, often performed inaccurately, and can be a barrier to optimal management. iSpy novel mobile app that leverages machine learning allow food identification through images was designed assist youth with type 1 in carbohydrates. Objective Our objective test the app's usability potential impact on carbohydrate accuracy. Methods Iterative testing (3 cycles) conducted involving total 16...
Abstract Background Endoscopy is essential for measuring luminal disease activity in Crohn’s (CD). Current endoscopic indices evaluating CD are limited: they only modestly correlated with activity, contain items that ambiguously defined and have poor inter-observer reliability, lack validated definitions clinically relevant change. We aimed to develop internally externally validate a reliable responsive index. Methods In this multi-part study, candidate index development face validity...
The performance of bowel preparation (BP) in patients with Crohn's disease (CD) is unknown.
We aimed to examine the associations between exposure air pollution and outcomes of preterm birth (PTB), term low weight (TLBW), small for gestational age.We conducted a population-based cohort study using perinatal database linked land-use regression-modeled data.Compared with women in lowest quartile toluene exposure, those second showed positive association PTB (odds ratio = 1.35, 95% confidence interval: 1.12, 1.63). A piecewise logistic regression breakpoint analysis identified cut...
Objective: The objective of this study was to evaluate the feasibility using virtual reality (VR) for distraction during intravenous (IV) insertion in pediatric emergency department (ED) and conducting a full-scale randomized controlled trial. Materials Methods: Children aged 8 17 years old attending tertiary care ED were interactive VR or an attention control (video on tablet) their IV insertion. Feasibility determined by recruitment rates, acceptability intervention, response rates outcome...
Abstract Seventeen children at six institutions with neurofibromatosis type 2 (NF2)‐related vestibular schwannomas received bevacizumab. Eight of the 13 patients initial hearing loss (61%) showed objective improvement within months treatment. No deterioration during therapy; however, only two radiological response. Seven eight had tumor progression or worsening upon cessation Bevacizumab was well tolerated no discontinuing therapy. appears to postpone in childhood NF2‐associated schwannomas,...
Body mass index (BMI) is commonly used to assess a child's weight status but it does not provide information about the distribution of body fat. Since disease risks associated with obesity are related amount and fat, measures that visceral or subcutaneous such as waist circumference (WC), waist-to-height ratio (WHtR), skinfolds thickness may be more suitable. The objective this study was develop percentile curves for BMI, WC, WHtR, sum 5 (SF5) in representative sample Canadian children...
Objective To model the development of tri-ponderal mass index (TMI, kg/m 3 ) throughout childhood and adolescence to compare utility TMI with that body (BMI, 2 predict cardiometabolic risk in a population-based sample Canadian children youth. Methods We used data from Health Measures Survey 6 19 years age. Percentile curves were developed using LMS method. Logistic regression was abnormal levels markers; predictive accuracy assessed area under ROC curve (AUC). Results Mean relatively stable...
To evaluate the implementation of an antimicrobial stewardship programme-led inpatient beta-lactam allergy de-labelling programme using a direct oral provocation test (OPT).
Equitable access to essential medicines is a key facet of childhood cancer care, recognised by WHO as vital improved outcomes globally. In the Caribbean, are poorer than those in most high-income countries. We aimed generate in-depth comparative evidence current challenges and opportunities related Caribbean identify context-sensitive health systems strategies improve drug inform evidence-based paediatric policies region. this convergent, parallel, mixed-methods study, we mapped analysed...
Health care workers have a critical role in the pandemic response to COVID-19 and may be at increased risk of infection. The objective this study was assess seroprevalence SARS-CoV-2 immunoglobulin G (IgG) antibodies among health during after first wave pandemic. We conducted prospective multicentre cohort involving Ontario, Canada, detect IgG against SARS-CoV-2. Blood samples self-reported questionnaires were obtained enrolment, 6 weeks 12 weeks. A community hospital, tertiary pediatric...
Background. Skinfold thickness (SFT) measurements are a reliable and feasible method for assessing body fat in children but their use interpretation is hindered by the scarcity of reference values representative populations children. The objective present study was to develop age- sex-specific percentile curves five SFT measures (biceps, triceps, subscapular, suprailiac, medial calf) population Canadian youth. Methods. We analyzed data from 3,938 adolescents between 6 19 years age who...