A5100460924- Retinal Imaging and Analysis
- Cerebrovascular and Carotid Artery Diseases
- Retinal Diseases and Treatments
- Acute Ischemic Stroke Management
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Intracranial Aneurysms: Treatment and Complications
- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Cardiovascular Health and Disease Prevention
- Artificial Intelligence in Healthcare
- Medical Imaging Techniques and Applications
- Moyamoya disease diagnosis and treatment
- Optical Coherence Tomography Applications
- Neurological Disease Mechanisms and Treatments
- Ophthalmology and Visual Impairment Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cancer Research and Treatments
- Antioxidant Activity and Oxidative Stress
- Chronic Kidney Disease and Diabetes
- Fire Detection and Safety Systems
- Periodontal Regeneration and Treatments
- Water Systems and Optimization
- Musculoskeletal synovial abnormalities and treatments
- Neuroscience and Neural Engineering
The First People's Hospital of Changzhou
2025
Soochow University
2020-2025
Third Affiliated Hospital of Sun Yat-sen University
2017-2024
Sun Yat-sen University
2017-2024
Capital Medical University
2011-2024
Henan University of Science and Technology
2023-2024
Beijing Children’s Hospital
2023
Beijing Chao-Yang Hospital
2021-2022
Jilin University
2022
Union Hospital
2022
Optical coherence tomography (OCT) is a new type of that has experienced rapid development and potential in recent years. It playing an increasingly important role retinopathy diagnoses. At present, due to the uneven distributions medical resources various regions, proficiency levels doctors grassroots remote areas, needs rare disease diagnosis precision medicine, artificial intelligence technology based on deep learning can provide fast, accurate, effective solutions for recognition retinal...
Mild cognitive impairment (MCI) is a pre-clinical stage of Alzheimer's disease afflicting large number the elderly throughout world. However, modifiable risk factors for onset and progression MCI remain unclear. A cross-sectional study was performed to explore whether how daily dietary nutrients intake lifestyle impacted in Chinese elderly. We examined 2,892 subjects, including 768 patients 2,124 subjects with normal cognition three different Provinces China. Dietary were collected by using...
Introduction The retina represents a critical ocular structure. Of the various ophthalmic afflictions, retinal pathologies have garnered considerable scientific interest, owing to their elevated prevalence and propensity induce blindness. Among clinical evaluation techniques employed in ophthalmology, optical coherence tomography (OCT) is most commonly utilized, as it permits non-invasive, rapid acquisition of high-resolution, cross-sectional images retina. Timely detection intervention can...
Fibrous dysplasia (FD) is the most common benign tumor of ribs, with surgical resection being preferred treatment modality for rib FD, leading to enhanced quality life and favorable outcomes. The complexity intervention varies depending on location costal presenting challenges both open thoracoscopic approaches. In this study, we present a novel technique three-port robotic-assisted costectomy utilizing Gigli saw, detailing our initial findings We reviewed five patients tumors who underwent...
Diabetic retinopathy is one of the most common microangiopathy in diabetes, essentially caused by abnormal blood glucose metabolism resulting from insufficient insulin secretion or reduced activity. Epidemiological survey results show that about third diabetes patients have signs diabetic retinopathy, and another may suffer serious threatens vision. However, pathogenesis still unclear, there no systematic method to detect onset disease effectively predict its occurrence. In this study, we...
Objectives: The molecular mechanism of postoperative cognitive dysfunction is largely unknown. Isoflurane has been shown to promote Alzheimer's disease neuropathogenesis. We set out determine whether the effect isoflurane on spatial memory associated with amyloid-beta (A-beta) levels and tau phosphorylation in aged rats.Methods: Eighteen-month-old male Sprague–Dawley rats were randomly assigned as anesthesia group (n = 31, received 1·4% for 2 hours had behavioral testing), training 20, no...
Visual sensitivity is comprehensively described by the contrast function (CSF), but current routine clinical care does not include its assessment because of time-consuming need to estimate thresholds for a large number spatial frequencies. The quick CSF method, however, dramatically reduces testing times using Bayesian information maximization rule. We evaluate test-retest variability tablet-based implementation in study with 100 subjects who repeatedly assessed their vision and without...
Background For nonmoyamoya patients with anterior cerebral artery (ACA) stenosis or occlusion, whether direct revascularization of the ACA territory can prevent stroke is still unclear. The objective this study was to investigate efficacy and safety a parietal branch superficial temporal artery-interposed artery-to-ACA bypass (PISAB) for preventing in symptomatic atherosclerotic occlusion (SAASO). Methods We retrospectively analyzed data from SAASO who had undergone PISAB our center between...
Objectives . To assess the underlying mechanisms of OIS and confirm haemodynamic retinal structure changes early OIS. Methods An observational cross-sectional study was conducted 60 internal carotid artery (ICA) stenosis patients, they were divided into control group. Colour doppler imaging, optical coherence tomography, fundus fluorescein angiography performed. Results The middle cerebral (MCA) differs significantly between two groups. More patients had new collateral patency posterior...
Objectives . To analyse the changes of ocular haemodynamics and morphology in Chinese patients with internal carotid artery (ICA) stenosis current study. Methods A retrospective case-control study was conducted 219 patients. The haemodynamic characteristics, calibre retinal vessels, subfoveal choroidal thickness (SFChT) were compared. We analysed correlations degree ipsilateral ICA stenosis. Results There no significant differences among groups central equivalent (CRAE), vein (CRVE), AVR...
Mendelian stroke causes nearly 7% of ischaemic strokes and is also an important aetiology cryptogenic stroke. Identifying the genetic abnormalities in as it would facilitate therapeutic management counselling. Next-generation sequencing makes large-scale testing possible.A systematic literature search was conducted to identify causal genes strokes, which were used construct a hybridization-based gene capture panel. Genetic variants for target detected using Illumina HiSeq X10 Novaseq...
Background : This study aims to evaluate ocular changes in patients with ischemic stroke using multimodal imaging and explore the predictive value of abnormalities for stroke. Methods A total 203 (ischemic group, 62; control 141) were enrolled this study. Basic data from patients, including age; gender; height; weight; history hypertension, hyperlipidemia, diabetes, alcohol use, coronary heart disease; smoking status, collected. Consequently, Doppler color ultrasound, fundus photography,...
BACKGROUND This study aimed to investigate the correlation of brain perfusion with white matter hyperintensity (WMH), atrophy, and cognition in patients moderate severe posterior cerebral artery stenosis (PCAS). MATERIAL AND METHODS 65 memory decline as main complaint no history infarction were recruited from Department Neurology Tongji Hospital. Patients PCAS included case group, subjects normal intracranial blood vessels served controls. The demographics vascular risk factors recorded....
Serial sectioning Optical Coherence Tomography (sOCT) is a high-throughput, label free microscopic imaging technique that becoming increasingly popular to study post-mortem neurovasculature. Quantitative analysis of the vasculature requires highly accurate segmentation; however, sOCT has low signal-to-noise-ratio and displays wide range contrasts artifacts depend on acquisition parameters. Furthermore, labeled data scarce extremely time consuming generate. Here, we leverage synthetic...
At present, there is no consensus on the treatment of common carotid artery occlusion (CCAO). We explored surgical indications and observed therapeutic effects carotid-carotid crossover bypass ring-stripping hybrid operation for Rile's type 1A CCAO.The imaging data, clinical manifestations, complications postoperative ischemic events were retrospectively collected from 6 cases with CCAO that underwent surgery in our department 2011 to 2018. Of cases, 4 received 2 operation.Of male females, a...