A5101510966- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic and Kidney Cyst Diseases
- Vascular Malformations and Hemangiomas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Mesenchymal stem cell research
- Gallbladder and Bile Duct Disorders
- CAR-T cell therapy research
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Imaging and Diagnostics
- Electrospun Nanofibers in Biomedical Applications
- Hemostasis and retained surgical items
- Extracellular vesicles in disease
- Facial Rejuvenation and Surgery Techniques
- Biliary and Gastrointestinal Fistulas
- Multiple Myeloma Research and Treatments
- Neurofibromatosis and Schwannoma Cases
- Renal cell carcinoma treatment
- Colorectal and Anal Carcinomas
- Neurogenesis and neuroplasticity mechanisms
- Diagnosis and treatment of tuberculosis
- AI in cancer detection
- Tuberculosis Research and Epidemiology
- Heme Oxygenase-1 and Carbon Monoxide
China-Japan Friendship Hospital
2014-2025
Shandong University of Traditional Chinese Medicine
2024
Beijing Chao-Yang Hospital
2019-2023
Capital Medical University
2019-2023
Qingdao University
2023
Cambridge University Hospitals NHS Foundation Trust
2023
Yuhuangding Hospital
2023
Duke University
2019-2021
Marcus (United States)
2020-2021
Duke Medical Center
2016-2021
714 Background: Over half of pancreatic cancer patients present with advanced disease and distant metastases, primarily in the liver, at initial diagnosis. Although systemic combination therapies have improved outcomes, role surgery remains contentious. This study seeks to pinpoint prognostic factors for synchronous liver metastatic (sPDACLM) who receive effective treatments, identify likely benefit from surgery. Methods: is a retrospective cohort study. Included received first-line...
BACKGROUND Hepatic hemangioma represents the most common benign primary hepatic neoplasm. Although such tumors are small and asymptomatic, giant cavernous (GCH) is frequently symptomatic, needs intervention. Moreover, diffuse hemangiomatosis (DHH) not rare in liver parenchyma adjacent to a GCH. The management strategy for hemangiomas can differ depending on presence of associated amount distribution residual parenchyma. CASE SUMMARY Herein, we report two patients with GCH coexistent DHH...
Abstract Mesenchymal stromal cells (MSCs) are widely used in clinical trials because of their ability to modulate inflammation. The success MSCs has been variable over 25 years, most likely due an incomplete understanding mechanism. After injected, they traffic the lungs and other tissues where rapidly cleared. Despite being cleared, suppress inflammatory response long term. Using human cord tissue-derived (hCT-MSCs), we demonstrated that hCT-MSCs directly interact reprogram monocytes...
Background Cholangiocarcinoma is a type of hepatobiliary tumor. For perihilar cholangiocarcinoma (pCCA), patients who experience early recurrence (ER) have poor prognosis. Preoperative accurate prediction postoperative ER can avoid unnecessary operation; however, challenging. Purpose To develop novel signature based on clinical and/or MRI radiomics features pCCA to preoperatively predict ER. Study Type Retrospective. Population One hundred eighty‐four (median age, 61.0 years; interquartile...
Microglia and monocytes play important roles in regulating brain remyelination. We developed DUOC-01, a cell therapy product intended for treatment of demyelinating diseases, from banked human umbilical cord blood (CB) mononuclear cells. Immunodepletion selection studies demonstrated that DUOC-01 cells are derived CB CD14+ monocytes. compared the ability freshly isolated to accelerate remyelination brains NOD/SCID/IL2Rγnull mice following cuprizone feeding-mediated demyelination. The corpus...
Transcatheter arterial embolization (TAE) is a method for the treatment of liver hemangioma, but fewer studies reported long-term result.Retrospective study was conducted to hemangioma patients who received TAE. The inclusion criteria included following: period follow-up more than 5 years; and were followed up less years, surgical due enlargement tumor or severe complications collected data sex, age, size tumor, times TAE, complications, follow-up, result, whether not surgery finally...
Gastrointestinal stromal tumor (GIST) is a common neoplasm with high rates of recurrence and metastasis, its therapeutic efficacy still not ideal. There an unmet need to find new molecular targets for GIST. TATA-box-binding protein-associated factor 15 (TAF15) contributes the progress various tumors, while role mechanism TAF15 in GIST progression are unknown.To explore understand biological underlying mechanisms progression.Proteomic analysis was performed differentially expressed proteins...
Radiofrequency ablation (RFA) is an effective and minimally invasive treatment for managing hepatic hemangiomas. Systemic inflammatory response syndrome (SIRS) often occurs with hemoglobinuria, its underlying pathophysiological mechanism unknown. Heme can trigger inflammation by inducing the generation of reactive oxygen species (ROS) production mediators. We therefore investigated whether circulating heme involved in SIRS following RFA hemangiomas.We enrolled 65 patients hemangioma who...
Background: Open enucleation (OE) is often performed for giant liver hemangioma (LH) because of its advantage in maximum preservation functional parenchyma. Laparoscopic (LE) has been applied to LHs more frequently potential advantages postoperative recovery and blood loss. However, date, LE still a difficult complex surgical technique especially when the located right hemi liver. The aim this study was analyze whether superior OE LH
The active ingredients of the Chinese medical herb Paris polyphylla, P. polyphylla ethanol extract (PPE) and polyphyllin I (PPI), potentially inhibit epithelial-mesenchymal transition (EMT) in tumors. However, roles these inhibiting EMT adenomyosis (AM) remain to be explored.
Borayflo Haemostatic matrix is a new absorbable hemostatic gelatin which can be used for intraoperative assisted hemostasis. In prospective, multicenter, non-inferiority, randomized controlled trial, total of 354 subjects were recruited from the departments hepatobiliary surgery, obstetrics and gynaecology orthopaedics 4 hospitals randomly allocated to test group (Borayflo matrix) or control (Surgiflo in 1:1 ratio. modified intention-to-treat population, 163 (93.14%) 175 versus 167 (94.89%)...
Objective To report three cases of localized primary sclerosing cholangitis (PSC) mimicking a hilar cholangiocarcinoma (Klatskin tumor) and to summarize their clinical characteristics the ways differentiate them through literature review.Method The data patients with PSC were retrospectively analyzed.The laboratory tests imaging examination reviewed,and therapy prognosis discussed.Results all diagnosed have preoperatively,but diagnosis was confirmed by histopathology post-operatively.All had...
Objective To summarize the experience of surgical treatments for giant liver hemangioma. Methods A retrospective study was made on clinical data patients with hemangioma larger than 10 cm in diameter, which were divided into two groups (10-<20 cm, 88 cases, ≥20 31 cases). Data included age and gender, presentation, treatment methods, peri-operative indexes, complications. Results All complained symptoms, average diameter (16±7)cm. There 23, 7, 17 cases respectively anemia,...