A5031449248- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Long-Term Effects of COVID-19
- Antibiotic Use and Resistance
- Gut microbiota and health
- Metabolomics and Mass Spectrometry Studies
- Atherosclerosis and Cardiovascular Diseases
- Nutrition and Health in Aging
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pregnancy and Medication Impact
- Macrophage Migration Inhibitory Factor
- Thyroid Disorders and Treatments
- Myasthenia Gravis and Thymoma
- CNS Lymphoma Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Abdominal vascular conditions and treatments
- Biomarkers in Disease Mechanisms
- Neuroblastoma Research and Treatments
- Renal cell carcinoma treatment
- Climate Change and Health Impacts
- Sex and Gender in Healthcare
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Lymphoma Diagnosis and Treatment
Koç University
2020-2024
Istanbul Medeniyet University
2017
Bernstein Center for Computational Neuroscience Tübingen
2010
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a complex involving alterations in multiple biological processes regulated by the interactions between obesity, genetic background, and environmental factors including microbiome. To decipher hepatic steatosis (HS) pathogenesis excluding critical confounding variants diabetes, 56 heterogenous MAFLD patients are characterized generating multiomics data oral gut metagenomics as well plasma metabolomics inflammatory proteomics...
Identifying a hypercoagulable state in patients with COVID-19 may help identify those at risk for virus–induced thromboembolic events and improve clinical outcomes using personalized therapeutic approaches. Herein, we aimed to perform global assessment of the patients’ hemostatic system rotational thromboelastometry (ROTEM) describe whether different disease severities present coagulation profiles. Together 37 healthy volunteers, total 65 were included then classified as having mild,...
This study aimed to examine fetomaternal outcomes in pregnant women a large Turkish Takayasu arteritis (TAK) cohort and evaluate the effects of pregnancy on disease those patients.This is involving 296 pregnancies 112 TAK patients from 8 tertiary rheumatology centers Turkey. Pregnancies were divided into 2 groups as pre-d (before onset) post-d (after onset). In addition, further subgroups according complications (FMC) development status. Finally, grouped with without history after onset.In...
ABSTRACT Nonalcoholic fatty liver disease (NAFLD) refers to excess fat accumulation in the liver. In animal experiments and human kinetic study, we found that administration of combined metabolic activators (CMA) promotes oxidation fat, attenuates resulting oxidative stress, activates mitochondria eventually removes from Here, tested safety efficacy CMA NAFLD patients a placebo-controlled 10-week study. We significantly decreased hepatic steatosis levels aspartate aminotransferase, alanine...
Prolonged Tp-Te interval is strongly associated with fatal ventricular arrhythmias and mortality. This association has been demonstrated in various diseases. However, the current literature does not give any information on cardiac amyloid light-chain (AL) amyloidosis.
Abstract Non-alcoholic fatty liver disease (NAFLD) is a complex involving alterations in multiple biological processes regulated by the interactions between obesity, genetic background and environmental factors including microbiome. To decipher hepatic steatosis (HS) pathogenesis excluding critical confounding variants, obesity diabetes, we characterized 56 heterogeneous NAFLD patients generating multi-omics data oral gut metagenomics as well plasma metabolomics inflammatory proteomics data....
This study aims to assess the level of pentraxin-3 (PTX-3) as an inflammatory marker and compare it with C-reactive protein (CRP) levels in patients Behçet's disease (BD).Forty-two BD (15 males, 27 females; mean age 39.7±8.6 years; range 20 64 years) 42 age- sex- matched healthy controls (14 28 40.8±8.2 year; 25 60 were included study. Serum CRP plasma PTX-3 measured. Subgroup analyses performed according clinical manifestations BD.Both significantly higher than (1.33±0.29 vs 0.85±0.12,...
We have previously found that combined metabolic cofactor supplementation (CMCS) promotes the oxidation of fat, attenuates resulting oxidative stress, activates mitochondria and eventually removes excess fat from liver. Here, we tested safety efficacy CMCS in Nonalcoholic fatty liver disease (NAFLD) patients a placebo-controlled 10-week study. significantly decreased hepatic steatosis levels aspartate aminotransferase, alanine uric acid, creatinine whereas no differences on these variables...
Reactive nitrogen species (RNS) such as nitric oxide (NO) can be produced by local pulmonary cells and inflammatory cells, they play a role in the pathogenesis of chronic diseases infections. NO is an unstable compound turning to more stable nitrite nitrate rapidly. The objective our study was investigate association between plasma nitrate+nitrite, nitrate, levels severity coronavirus disease (COVID)-19. Blood samples mild, moderate, severe COVID-19 patients were collected from 2 different...
Abstract Background: Throughout the pandemic, physicians working at frontlines have embarked on various quests to protect themselves, and many preferred use of hydroxychloroquine (HQN) as a prophylactic agent. This study aimed investigate reasons leading HQN effects physicians. Methods: is cross-sectional with target population in pandemic hospitals İstanbul, Turkey. We recruited participants from seven different via an invitation email between May 14 June 13, 2020. An online questionnaire,...
Objectives: Atherosclerotic cardiovascular disease risk is increased in hemodialysis patients. Oxidized low density lipoprotein has an important role atherosclerotic process and it exerts this effect via lectin like oxidized lipoprotein-1 (LOX-1). Carotid artery intima-media thickness (CIMT) accepted as a god indicator of subclinical atherosclerosis. In study, we aimed to investigate LOX-1 CIMT levels Methods: Twenty-eight patients treated with at least 6 months 19 healthy subjects were...
Objective: Throughout the pandemic, physicians working at frontlines have embarked on various quests to protect themselves, and many preferred using hydroxychloroquine (HQN) as a prophylactic agent. This study aimed investigate reasons leading use HQN its effects them. Materials Methods: is cross-sectional with target population of in pandemic hospitals İstanbul, Turkey. We invited participants from seven via email between May 14 June 13, 2020. An online questionnaire, including 57...