- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Cardiac and Coronary Surgery Techniques
- Cell death mechanisms and regulation
- Protein Kinase Regulation and GTPase Signaling
- Transplantation: Methods and Outcomes
- Coronary Artery Anomalies
- Pleural and Pulmonary Diseases
- Surgical site infection prevention
- Arsenic contamination and mitigation
- Tracheal and airway disorders
- Mitochondrial Function and Pathology
- Hemostasis and retained surgical items
- Autoimmune Bullous Skin Diseases
- Phosphodiesterase function and regulation
- Cardiac Ischemia and Reperfusion
- Cardiovascular Conditions and Treatments
- Anesthesia and Neurotoxicity Research
- Uterine Myomas and Treatments
Children's Healthcare of Atlanta
2011-2024
Derriford Hospital
2002-2024
Emory University
1976-2021
Cook Children's Medical Center
2016-2017
Freeman Hospital
1994
Royal London Hospital
1993
Woodruff Health Sciences Center
1982
Background The Occlutech Atrial Flow Regulator (AFR) is a self-expandable double-disc nitinol device with central fenestration. Its use has been approved in the adult population heart failure and described for pulmonary hypertension (PH). Only case reports small series have published about its paediatric congenital disease (CHD). Objectives authors sought to investigate feasibility, safety, short-term follow-up of AFR implantation patients CHD or children PH cardiomyopathy. Methods This...
Biological valves are the most commonly implanted prostheses for aortic valve replacement (AVR) surgery in UK. The aim of this study was to compare performance porcine and bovine pericardial AVR with respect survival reintervention-free a retrospective observational study. Prospectively collected clinical data all first-time elective urgent AVRs or without concomitant coronary artery bypass graft (CABG) performed England Wales between April 2003 March 2013 were extracted from National...
Oxygen free radicals (OFRs) are associated with ischaemia-reperfusion injury involving many organs, including the heart, which can lead to depressed cardiac function and abnormalities in ultrastructure. This is seen upon release of aortic crossclamp when ischaemic myocardium reperfused patients undergoing cardiopulmonary bypass (CPB). 1 Various studies have shown that by adding OFR scavenging agents or antioxidants CPB prime cardioplegia, performance improves. 2,3 Mannitol an osmotic...
Uterine leiomyosarcoma is a rare malignant tumor of smooth muscle origin. We describe the case 64-year-old female with intravenous uterine leiomyosarcomatosis extension mass into inferior vena cava and right atrium. As initial tissue diagnosis obtained from atrial masses suggested leiomyomatosis, surgical resection was carried out using one-stage procedure via laparotomy median sternotomy cardiopulmonary bypass circulatory arrest. Subsequent histology revealed an spread, which to our...
The aim of this study is to estimate annual, per patient, health care costs for congenital ichthyoses (CI). We conducted a cost analysis through an online survey posted on the Foundation Ichthyosis and Related Skin Types Website. assessed cutaneous disease severity, via previously validated Congenital Severity Index (CISI), demographics, CI type. estimated direct costs: prescription over-the-counter medications, outpatient visits, emergency department hospital visit costs; indirect earnings...
Pulmonary vein stenosis (PVS) is a difficult condition to treat due recurrence and progression. In 2017, we developed comprehensive PVS Program at our center address the multidisciplinary needs of these patients. We discuss components program approach patients, using combination primary (medical) therapy in addition anatomic preserve vessel patency. A treating challenging patients critical.
The Melody transcatheter pulmonary valve has been implanted successfully worldwide since its first implant in 2000. vast majority of these valves have homografts. In our institution, the most common used for replacement is Medtronic Freestyle stentless porcine aortic heterograft.We describe experience implanting within heterograft.Retrospective chart review was performed.Between June 2012 and 2015, 19 were placed heterografts. indication intervention stenosis. Following pre-stent...
PVS is a challenging condition characterized by high rates of progression and re-stenosis low freedom from interventions. Sirolimus has emerged as promising therapeutic option with studies showing improved survival decrease in rate in-stent stenosis. There is, however, lack published experience long term therapy we consensus regarding the ideal duration therapy. We share our use particularly looking at its impact on need for catheter interventions related admissions. Single center...