A5021789871- COVID-19 Clinical Research Studies
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Long-Term Effects of COVID-19
- Healthcare Systems and Public Health
- Multiple and Secondary Primary Cancers
- Diet, Metabolism, and Disease
- Colorectal Cancer Screening and Detection
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Pancreatic function and diabetes
- Chronic Kidney Disease and Diabetes
- Gut microbiota and health
- Colorectal Cancer Surgical Treatments
- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Biomarkers in Disease Mechanisms
- Neurological Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Cardiovascular Function and Risk Factors
- Ultrasonics and Acoustic Wave Propagation
- Economic and Financial Impacts of Cancer
- Sarcoidosis and Beryllium Toxicity Research
- Medical and Agricultural Research Studies
- COVID-19 and healthcare impacts
Kyrgyz State Medical Academy
2019-2025
Kazakh Scientific Research Veterinary Institute
2023
International Higher School of Medicine
2022
International University of Kyrgyzstan
2022
Kyrgyz-Russian Slavic University named after B.N. Yeltsin
2019-2021
The successful application of messenger RNA (mRNA)-based vaccines for the prevention COVID-19 infection has drawn attention scientific community to potential clinical applications these molecules as innovative and alternative therapeutic approaches in various fields medicine. As agents, mRNAs may be advantageous due their unique biological properties – ability target virtually any genetic component cell encode proteins peptides without need transfer them nuclei cells. In addition, can...
The aim is to study the trends of liver cancer (LC) incidence in regional context Kazakhstan.
Objective: The epidemiological features of the breast cancer (BC) incidence in Kyrgyzstan were studied. Methods: retrospective study (2003-2017). Descriptive and analytical methods oncoepidemiology used. Crude (CR), age-specific (ASIR), age-standardized (ASR), equalized rates approximation calculated. method drawing up a cartogram based on determination standard deviation (σ) from mean (x) was applied. Results: During period, 7,850 new cases BC registered. average annual crude rate 18.8±0.5...
Abstract The knowledge about the features of energy metabolism in MAFLD population living at different climatic and geographic heights is lacking. goal this study to explore biochemical parameters blood erythrocyte consumption patients with without DM2 low- moderate-altitude regions Central Asia. Our was carried out on low-altitude mountains: Bishkek, altitude=750–800 m; n=67 (MAFLD DM 2: n=24; DM2: n=25; control: n=18), At-Bashy District, Naryn Region, altitude=2046–2300 n=58 n=28; n=18;...
Introduction and Aim: Breast cancer (BC) is the world's leading oncological disease in terms of prevalence among females accounts for 25% all diseases affecting female population, women are from age 50–60 years. The aim study was to determine risk factors development BC Kyrgyzstan (well–known, specific, protective). Methods: This a retrospective that analyzed medical records outpatient 1024 patients with treated at National Center Oncology Hematology Ministry Health 2016–2021. Results:...
Nowadays, drip irrigation is a promising technology for optimizing plant development conditions and allowing the introduction of necessary nutrients to plants. The study aimed establish effects with various levels foliar dressing mineral fertilizer Kristalon on maize (Zea mays L.) achieve its maximum genetic potential grain yield enhance overall production. A field experiment implies exploratory research quantifies validate introduce scientific achievements in agricultural Various...
Objective assessment of the renal status, d-dimer and procalcitonin levels in patients with novel coronavirus disease (COVID-19) material methods: study included 123 diagnosed covid-19 pneumonia indices estimated glomerular filtration rate (egfr) were considered according to ckd-epi (Chronic kidney epidemiology Collaboration) mdrd (Modification Diet Disease) formulas The creatinine clearan concentration creatinine, d-dimer, determined results median interquartile egfr values 80 o (68 0;95 0)...
Бас редактор ЖҰРЫНОВ Мұрат Жұрынұлы, химия ғылымдарының докторы, профессор, ҚР ҰҒА академигі, Қазақстан Республикасы Ұлттық Ғылым академиясының президенті, АҚ «Д
Objective: The aim is to study the trends of lung cancer (LC) incidence in regional context Kazakhstan. Methods: retrospective was done using descriptive and analytical methods oncoepidemiology. extensive, crude age-specific rates are determined according generally accepted methodology used sanitary statistics. data were calculate average percentage change (APС) Joinpoint regression analysis determine trend over period. Results: Over 10 years under study, 36,916 new cases LC registered...
Introduction Worldwide, there has been an increase in the incidence of metabolic syndrome. The search for genetic markers this syndrome is ongoing. leptin receptor recently received attention. One polymorphisms (Gln223Arg) possibly associated with development obesity and insulin resistance. However, results studies on polymorphism remain equivocal. Gln223Arg not studied previously Kyrgyz population. Thus, we aimed to investigate possible association gene components Material methods 237...
The aim is to study the trends in gastric cancer (GC) mortality Kazakhstan.Data on those who died from GC and annual population were obtained Bureau of National Statistics Agency for Strategic Planning Reforms Republic Kazakhstan. A retrospective was carried out period 2009-2018 using descriptive analytical methods oncoepidemiology. extensive, crude age-specific rates are determined according generally accepted methodology used sanitary statistics.GC Kazakhstan considered be decreasing. It...
Статья посвящена поражению мышечной системы при новой коронавирусной инфекции (COVID-19). Проведен анализ литературы российских и иностранных исследователей по внелегочным проявлениям COVID-19. Главной мишенью COVID-19 (Corona Virus Disease 2019) является эндотелий сосудов. Для проникновения в клетки вирус использует рецептор — ангиотензинпревращающий фермент 2 (АПФ2). Показано, что к одной мишени могут присоединиться до трех вирусов. В скелетной мускулатуре также имеется АПФ2. При...
A new strain of coronavirus — SARS-CoV-2 (Severe Acute Respiratory Syndrome CorOnaVirus-2) has caused an increase in the number cases and high mortality worldwide. In patients with disease 2019 (COVID-19, Corona Virus Disease 19), addition to lung damage, there is a risk developing multiple organ failure. Concomitant cardiovascular diseases are independent factors for development severe forms COVID-19. COVID-19 manifested by polysegmental pneumonia, pulmonary edema, sepsis, atrial or...
The article is devoted to an urgent problem - kidney damage in diabetes mellitus. analysis of Russian and foreign sources literature on diabetic nephropathy has been carried out. Data the prevalence are presented, role individual risk factors for development progression discussed.
One of the important problems modern society is prevention and treatment cancer. To increase effectiveness existing methods, it promising to use biological response modifiers, combination which with traditional methods makes possible therapy. The article presents results experiments studying combined effects metformin, low molecular weight pectin cytostatic drug gemcitabine on a transplantable tumor — Walker carcinosarcoma 256. experimental demonstrated clear effect reducing toxicity when...
Background . Currently, in most countries of the world, there is a tendency for an annual increase proportion overweight people (OW). Studies performed various age groups and devoted to relationship OW with functional state kidneys show contradictory results. The aim : study prevalence risk factors cardiovascular complications OW, taking into account gender differences. Patients Methods A cross–sectional single-center was conducted participation 154 patients (73 men 81 women) body mass index...
Despite certain success achieved in therapy and prevention, cardiovascular diseases (CVD) continue to be the leading cause of death population worldwide. One main reasons for this is that pathophysiological mechanisms development atherosclerosis, a disease underlies most clinical forms CVD, have not been fully understood yet, based on well-known concepts pathogenesis, including lipid, does provide desired results. In regard, search identification new molecular targets therapeutic approaches...
Рак шейки матки занимает одну из лидирующих позиций в структуре злокачественных новообразований органов репродуктивной системы. Лечение при локализованных формах рака дает хорошие результаты общей 5-летней и безрецидивной выживаемости. А местнораспространенных формах, учитывая относительно низкие показатели отдаленных результатов, выбор оптимальной тактики лечения до сих пор остается дискутабельным. Цель работы: изучить частоту виды ранних осложнений после хирургического лучевого лечений...
Objective: To study the features of incidence prostate cancer in two major megacities Kazakhstan – cities Almaty and Astana.Methods. The material was data Ministry Health Republic annual form No.7 concerning (ICD 10 C61) for 2005-2019. A retrospective using descriptive analytical methods biomedical statistics used as main method.Results. In 2005-2019, 14,740 new cases PC were registered Kazakhstan, which only 2,296 (15.6%) 625 (4.2%) patients accounted Astana, respectively. average age...
The aim is to analyze the incidence of kidney cancer over a 15-year period, considering factors such as stage, age, sex, and morphological verification in regional context Kazakhstan.
Background: According to the International Agency for Research on Cancer, ongoing demographic changes will lead an increase in number of deaths from breast cancer (BC) per year vast majority regions. In 2040 it is expected that 1.04 million people worldwide die this malignancy, including 2,380 women Kazakhstan. Methods: The retrospective study (2009-2018) was done using descriptive and analytical methods oncoepidemiology. extensive, crude age-specific incidence rates are determined according...
Infectious disease COVID-19 caused by the SARS-CoV-2 coronavirus is characterized high contagiousness, complexity of pathogenesis and unpredictability clinical course. In severe cases, which are especially susceptible to men, elderly people with underlying medical conditions such as obesity, diabetes, hypertension, cardiovascular chronic respiratory diseases, infection leads failure death due development an extensive inflammatory reaction. As a result many studies, it has been established...