A5049556902- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Myasthenia Gravis and Thymoma
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Pectus Deformity Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Adrenal and Paraganglionic Tumors
- Neuroblastoma Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- Soft tissue tumors and treatment
- Cardiac tumors and thrombi
- Medical Imaging Techniques and Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Meningioma and schwannoma management
- Soft tissue tumor case studies
- Inflammatory Biomarkers in Disease Prognosis
- Anorectal Disease Treatments and Outcomes
- Neuroendocrine Tumor Research Advances
- Management of metastatic bone disease
Keio University
2014-2024
Keio University Hospital
2017-2023
National Sagamihara Hospital
2014-2017
Tokyo Metropolitan Komagome Hospital
2009-2014
National Cancer Center Hospital East
2013
The aim of this study was to evaluate the diagnostic accuracy integrated (18) F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in hilar and mediastinal lymph node (HMLN) staging non-small cell lung cancer (NSCLC), investigate potential risk factors for false-negative false-positive HMLN metastases.We examined data 388 surgically resected NSCLC patients preoperatively staged by FDG-PET/CT. Risk metastases were analyzed using univariate multivariate analyses...
Histological vascular invasion ( VI ) by tumors is reportedly a risk factor influencing recurrence or survival after surgical treatment; however, few studies have evaluated which features affect survival. The objective of this study was to evaluate how in lung adenocarcinoma patients. We selected 106 patients with pathological stage I who showed and examined the properties intravascular associated recurrence. First we investigated relationship between frequency histological cross‐section...
Solitary papilloma of the lung is thought to be a rare benign epithelial tumor, and complete surgical resection currently standard treatment for this pathology. However, some cases have reportedly shown malignant potential. We report two solitary glandular peripheral that were treated by thoracoscopic partial resection. The first patient presented with nodular lesion in lower lobe left was detected on follow-up chest computed tomography (CT) scan after laryngeal cancer. Partial performed...
The finding of pulmonary arterial enlargement on computed tomography has been reported to be associated with hypertension. On the other hand, hypertension is a known risk factor for thoracic surgery. We investigated whether predicts cardiopulmonary complications following resection lung cancer.We reviewed 237 consecutive patients who underwent cancer. Preoperative patient characteristics (sex, age, Brinkman index, comorbidities, cardiothoracic ratio, function, and enlargement) surgical data...
Plasma D-dimer level, a marker of hypercoagulation, has been reported to be associated with survival in several types cancers. The present study aimed evaluate the prognostic significance preoperative levels patients surgically resected clinical stage I non-small cell lung cancer (NSCLC).Participants comprised 237 NSCLC. In addition factors such as age, sex, and smoking status, association between level was explored.Patients were divided into two groups according level: Group A, ≤ 1.0 μg/ml...
Debulking surgery, also called cytoreductive is a resection of the tumor as much possible and an intended incomplete for unresectable malignant tumors. Since most important principle in surgical oncology complete R0 resection, debulking surgery goes against basic obscures concept operability. However, has been advocated various types advanced tumors, including gynecological cancers, urological gastrointestinal breast cancers other malignancies, with or without adjuvant therapy. Positive data...
In our institution, computed tomography (CT)-guided percutaneous cryoablation has been performed in patients with malignant lung tumors under local anesthesia. This study aimed to examine the feasibility and safety of for treatment tumors.From July 2002 December 2016, 227 (56 primary cancer 171 metastatic tumor) underwent using a cryosurgical unit at institution. Demographic factors, duration post-treatment hospitalization, adverse event mortality rates were retrospectively investigated 366...
Sarcomatoid carcinoma of the lung is a rare histological type non-small cell cancer with poor prognosis. We aimed to investigate clinicopathological characteristics and prognostic factors surgically resected sarcomatoid lung. retrospectively reviewed 14999 patients who underwent surgical resection for accumulated by Japanese Joint Committee Lung Cancer Registry in 2010. Clinicopathological survival were compared between other groups. The group identified using multivariate Cox proportional...
Pulmonary metastases from thyroid carcinoma typically cause a micronodular or miliary pattern throughout both lungs. Metastasis consisting of solitary pulmonary nodule measuring 20 mm in diameter is rare. Here we report case 66-year-old woman without history papillary who presented with diameter, found on chest computed tomography during health checkup. The patient underwent right lobectomy. Microscopic examination showed well-differentiated adenocarcinoma. Immunohistochemical findings were...
The prevalence of salvage surgeries after drug therapy for non-small cell lung cancer (NSCLC) has risen, mainly due to recent progress in molecular-targeted drugs and immune checkpoint inhibitors NSCLC. While the safety effectiveness surgery NSCLC have been studied, its indications remain unclear. We aimed identify prognostic factors affecting survival patients with advanced-stage (stages III-IV) treated therapy.A retrospective investigation was conducted on who received at four hospitals...
Prognostic factors for patients with non‐small cell lung cancer ( NSCLC ) who have been treated neoadjuvant therapy not fully assessed. The purpose of this study was to analyze prognostic biomarkers in after treatment therapy, special reference the immunophenotypes both cells and stromal cells. A total 52 were followed by complete resection included. We examined expressions nine markers 5‐year disease‐free survival rate high aldehyde dehydrogenase 1 ALDH1 expression levels their...
Background This study aimed to evaluate mutations of the epidermal growth factor receptor ( EGFR ) and K ‐ ras genes their clinicopathological prognostic features in patients with resected pathological stage I adenocarcinoma. Methods We examined 224 surgically lung adenocarcinoma analyzed predictive value these 162 Results Mutations were detected 100 (44.6%) 19 (8.5%) all tumors, 81 (50.0%) 17 (10.5%) respectively. significantly associated female gender, smoking habit (never smoker), low...
Abstract Background The aim of this study was to investigate the clinicopathological and prognostic features operable non‐small cell lung cancer (NSCLC) patients with diabetes mellitus (DM). Methods A total 1231 surgically resected NSCLC were retrospectively reviewed. Clinicopathological characteristics compared between DM (DM group, n = 139) those without (non‐DM 1092). clinical factors associated postoperative complications identified. Results group had distinct features. No significant...
A 45-year-old female was diagnosed as having lung adenocarcinoma harboring an anaplastic lymphoma kinase (ALK) rearrangement, stage IV (T2bN3M1b). She treated with crizotinib second-line chemotherapy. The clinical after treatment ycT2aN0M0, IB. We performed a left lower lobectomy and lymph node dissection aimed at local control pathological confirmation of the remaining tumor. final ypT2aN2M0, IIIA Ef 1b. To best our knowledge, this is first case report surgical resection in ALK...