A5102802826- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neurofibromatosis and Schwannoma Cases
- Peripheral Nerve Disorders
- Cancer Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Genetic factors in colorectal cancer
- Gallbladder and Bile Duct Disorders
- Sarcoma Diagnosis and Treatment
- Shoulder Injury and Treatment
- Nerve Injury and Rehabilitation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Metastasis and carcinoma case studies
- Salivary Gland Tumors Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Oral and Maxillofacial Pathology
- Risk Perception and Management
- Ear and Head Tumors
- Occupational exposure and asthma
- Craniofacial Disorders and Treatments
Keio University
2014-2024
National Sagamihara Hospital
2003-2023
Hirosaki University Hospital
2022
Tsuchiura Kyodo General Hospital
2020
Keio University Hospital
2020
Tokyo National Hospital
2016-2018
National Cancer Center Hospital East
2016
Tokyo Metropolitan Komagome Hospital
2011-2013
Nihon University
2011
Akita University
2011
BackgroundInvasion is a crucial indicator of the prognosis in lung adenocarcinoma. The 2015 WHO classification tumors defined invasion adenocarcinoma mainly by presence non-lepidic histological subtypes including papillary, acinar, micropapillary and solid patterns, cancer-associated active fibroblasts (CAF). In this study, we focused specifically on early-stage lepidic with CAF to evaluate its prognostic significance.MethodsWe included 1032 resected cases adenocarcinoma, which consisted...
Sarcopenia characterized by skeletal muscle loss may influence postoperative outcomes through physical decline and weakened immunity. We aimed to investigate clinical significance of sarcopenia in resected early-stage non-small cell lung cancer (NSCLC).We retrospectively reviewed 315 consecutive patients with pathologic stage I NSCLC who had undergone lobectomy systematic nodal dissection. was defined as the lowest quartile psoas area on 3rd vertebra high-resolution computed tomography...
Abstract We conducted a prospective single-arm interventional study of the treatment efficacy ultrasound-guided fascia hydrorelease (US-FHR) on coracohumeral ligament (CHL) patients with global limitation shoulder range motion (ROM) without local inflammation. The primary outcome was change in passive ROM (pROM) external rotation (ER) after first US-FHR. Secondary outcomes included pROM other directions from baseline, pain visual analogue scale (pVAS) at timepoints each procedure (first,...
Colloid adenocarcinoma of the lung (CA) is a rare neoplasm that associated with abundant mucin, which destroys alveoli. We evaluated clinicopathological features CA.A total 4,648 patients underwent surgical resection primary cancer at our institution from 2002 to 2014. analyzed CA in six (0.13%) these patients.All were asymptomatic. The median age was 60.5 years. tumor size 2.4 cm. All tumors appeared as solitary solid nodules on computed tomography (CT). Four showed intense (18)...
The prevalence of salvage surgeries after drug therapy for non-small cell lung cancer (NSCLC) has risen, mainly due to recent progress in molecular-targeted drugs and immune checkpoint inhibitors NSCLC. While the safety effectiveness surgery NSCLC have been studied, its indications remain unclear. We aimed identify prognostic factors affecting survival patients with advanced-stage (stages III-IV) treated therapy.A retrospective investigation was conducted on who received at four hospitals...
Pulmonary glandular papillomas are rare neoplasms, and their very slow or absent growth over time generally facilitates establishing the diagnosis. In an 84-year-old woman who underwent surgery for sigmoid colon cancer, a growing solitary pulmonary nodule was identified on postoperative follow-up computed tomography. A computer tomography-guided needle biopsy performed under suspicion that malignant. The histopathological findings suggested papilloma. Right basilar segmentectomy carried out,...
The adhesion-preventing effect of trehalose in visceral organs was evaluated a rabbit model. All rabbits underwent hysterotomy, during which mild abrasion and desiccation induced on the surfaces organs. In control group, intestines were kept dry hysterotomy. saline groups, solution 7% solution, respectively, sprayed organ surfaces. Adhesion formation declined significantly group compared with other groups. contrast, at hysterotomy site, there no significant difference adhesions between...
Tracheal intubation is associated with various complications that include epithelial injury. Abrasion of the fragile tracheal epithelium can occur at points contact between tube and mucosa subject to respiratory movement. In this original experiment, we examined mucosal protective effect coating endotracheal tubes poly[2-methacryloyloxyethl phosphorylcholine (MPC)-co-n-butyl methacrylate] (PMB).We prepared four types tubes: A (control, no coating), B (two coats, 0.5% PMB), C (10 PMB) or D...
Abstract Background Although completion lobectomy is the treatment of choice for local recurrence non-small cell lung cancer after segmentectomy, few cases have been reported. We report four patients who underwent lobectomies staple line segmentectomy stage I cancer. Case presentation Three women aged 65, 82, and 81 years lower superior same lobe A 67-year-old man, had a tumor on apical with mediastinal nodal dissection cancer, right upper lobectomy. These because comorbidities or advanced...
Exclusion of patients with a history other cancer treatment except in situ situation has been considered to be inevitable for clinical trials investigating survival outcome. However, there have few reports confirming these influences on surgical outcome lung ever.Multi-institutional, individual data from non–small cell resected between 2000 and 2013 were collected. The divided into two groups: those gastrointestinal tract (GI group) without any (non-GI group). We compared the outcomes...
A collision tumor of the lung is relatively rare. We report a case 72-year-old man with consisting three neoplastic components in underlying interstitial disease. Computed tomography showed parenchymal lesion an air bronchogram. Transthoracic needle biopsy chronic inflammation, however, malignant pulmonary was clinically suspected. The patient underwent right lower lobectomy mediastinal lymph node dissection. histological features surgical specimen cancer components, which were squamous cell...
Trehalose has several novel anti-inflammatory and cell-protective functions. We hypothesized that lyophilized aspirin/trehalose could decrease the severity of aspirin-induced gastropathy. Thirteen dogs were assigned into aspirin, aspirin/trehalose, control groups, gastric lesions assessed on gastroscopy with modified Lanza scale. Another 6 used to measure plasma aspirin concentration by high-performance liquid chromatography after or administration. The results indicated induced less...