A5086127198- Motor Control and Adaptation
- Muscle activation and electromyography studies
- Visual perception and processing mechanisms
- Action Observation and Synchronization
- Tactile and Sensory Interactions
- EEG and Brain-Computer Interfaces
- Astrophysics and Cosmic Phenomena
- Particle physics theoretical and experimental studies
- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neural Engineering
- Vestibular and auditory disorders
- Stroke Rehabilitation and Recovery
- Neutrino Physics Research
- Dark Matter and Cosmic Phenomena
- Sport Psychology and Performance
- Multisensory perception and integration
- Medical Imaging and Analysis
- Face Recognition and Perception
- Balance, Gait, and Falls Prevention
- Child and Animal Learning Development
- Pediatric Urology and Nephrology Studies
- Particle Detector Development and Performance
- Urinary Tract Infections Management
University of Bologna
2015-2024
Mater Research
2024
Institut d'Astrophysique de Paris
2024
Ospedale Filippo Del Ponte Varese
2022
Ospedale Civile di Venezia
2016
Istituto Nazionale di Fisica Nucleare, Sezione di Milano
2016
Brown University
1998-1999
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Gran Sasso
1994-1995
Brain control of prehension is thought to rely on two specific brain circuits: a dorsomedial one (involving the areas superior parietal lobule and dorsal premotor cortex) involved in transport hand toward object dorsolateral inferior ventral dealing with preshaping according features object. The present study aimed at testing whether pivotal component pathway (area V6A) also grip formation grasp objects different shapes. Two macaque monkeys were trained reach objects. For each object,...
Reach-to-grasp actions involve several components of forelimb movements needed to direct the hand toward object be grasped, and orient preshape according axis shape. Area V6A, which represents a node dorsomedial frontoparietal circuits, has so far been implicated only in directing arm different spatial locations. The present results confirm this finding demonstrate, for first time, that during reach-to-grasp, V6A neurons are also modulated by orientation hand. In work grasped was handle...
The visuomotor medial posterior parietal area V6A has been recently subdivided into two cytoarchitectonic sectors called V6Ad and V6Av (Luppino et al., 2005). aim of the present study was to recognize whether these cortical show different functional profiles. Fourteen hemispheres from eight animals (Macaca fascicularis) were included in this study, for a total 3828 extracellularly recorded neurons assigned areas or on cytoarchitectural basis. sensitivity sensory- motor-related activities...
Area V6A encodes hand configurations for grasping objects (Fattori et al., 2010). The aim of the present study was to investigate whether cells also encode three-dimensional objects, and relationship between object encoding grip encoding. Single neurons were recorded in two monkeys trained perform tasks. In first task, required passively view an without performing any action on it. second viewed at beginning each trial then they needed grasp that darkness. Five different used. Both tasks...
Many psychophysical studies suggest that target depth and direction during reaches are processed independently, but the neurophysiological support to this view is so far limited. Here, we investigated representation of reach by single neurons in area V6A medial posterior parietal cortex (PPC) macaques, while a fixation-to-reach task 3-dimensional (3D) space was performed. We found that, substantial percentage neurons, signals jointly influenced fixation, planning, arm movement-related...
We present an analysis of muon events with all multiplicities collected during 21804 h operation the first Large Volume Detector tower. The measured angular distribution intensity has been converted to "depth–vertical-intensity" relation in depth range from 3 12 km w.e. this allowed us derive power index γ primary all-nucleon spectrum: γ=2.78±0.05. standard rock and comparison data other experiments done. also derived vertical spectrum at sea level.Received April...
Reaching and grasping an object is action that can be performed in light, as well darkness. Area V6A a visuomotor area of the medial posterior parietal cortex involved control reaching movements. It contains neurons modulated by passive somatosensory visual stimulations. In present work we analyze effect feedback on activity neurons. Three macaques were trained to execute movements two conditions: darkness, where only target was visible, full monkey also saw its own moving arm environment....
Eye position signals are pivotal in the visuomotor transformations performed by posterior parietal cortex (PPC), but to date there few studies addressing influence of vergence angle upon single PPC neurons. In present study, we investigated on neurons medial area V6A and version signals. Single-unit activity was recorded from two Macaca fascicularis fixating real targets darkness. The fixation were placed at eye level different angles within peripersonal space. Few modulated or only, while...
Interacting in the peripersonal space requires coordinated arm and eye movements to visual targets depth. In primates, medial posterior parietal cortex (PPC) represents a crucial node process of visual-to-motor signal transformations. The PPC area V6A is key region engaged control these processes because it jointly information, position movement related signals. However, date, there no evidence spatial encoding three dimensions. Here, using single neuron recordings behaving macaques, we...
Background Attention is used to enhance neural processing of selected parts a visual scene. It increases responses stimuli near target locations and usually coupled eye movements. Covert attention shifts, however, decouple the attentional focus from gaze, allowing direct peripheral location without moving eyes. We tested whether covert shifts modulate ongoing neuronal activity in cortical area V6A, an that provides bridge between signals arm-motor control. Methodology/Principal Findings...
Abstract Spatial representations in cortical areas involved reaching movements were traditionally studied a frontoparallel plane where the two-dimensional target location and movement direction only variables to consider neural computations. No studies so far have characterized reference frames for considering both depth directional signals. Here we recorded from single neurons of medial posterior parietal area V6A during task fixation point targets decoupled depth. We found prevalent mixed...
Abstract Recent works have reported that grasping movements are controlled not only by the dorsolateral visual stream, as generally thought, but also dorsomedial and in particular medial posterior parietal area V6A. To date, activity of V6A neurons has been studied darkness. Here we effect feedback on grasp-related discharges while monkey was preparing executing a handle. We found could be excited or inhibited information. The neural population divided into Visual, Motor, Visuomotor cells....
Research conducted over the last decades has established that medial part of posterior parietal cortex (PPC) is crucial for controlling visually guided actions in human and non-human primates. Within this cortical sector there area V6A, a node parietofrontal network involved arm movement control both monkeys humans. However, encoding action-in-depth by V6A cells had been not studied till recently. Recent neurophysiological studies show existence neurons signals related to distance targets...
When saccadic eye movements consistently fail to land on the intended target, saccade accuracy is maintained by gradually adapting amplitude of successive saccades same target. Such adaptation usually induced systematically displacing a small visual target during execution saccade. However, are normally performed extended objects. Here we report changes in when size object changed Moreover, find that this manipulation also affected perception object. Human subjects were tested shortening and...
Neurodecoders have been developed by researchers mostly to control neuroprosthetic devices, but also shed new light on neural functions. In this study, we show that signals representing grip configurations can be reliably decoded from data acquired area V6A of the monkey medial posterior parietal cortex. Two Macaca fascicularis monkeys were trained perform an instructed-delay reach-to-grasp task in dark and toward objects different shapes. Population activity was extracted at various time...
The posterior parietal cortex is well known to mediate sensorimotor transformations during the generation of movement plans, but its ability control prosthetic limbs in 3D environments has not yet been fully demonstrated. With this aim, we trained monkeys perform reaches targets located at various depths and directions tested whether reach goal position can be extracted from signals. location was reliably decoded with accuracy close optimal (>90%), occurred also before onset. These results,...
Area V6A is a visuomotor area of the dorsomedial visual stream that contains cells modulated by object observation and grip formation. As different objects have shapes but also evoke grips, response selectivity during presentation could reflect either coding geometry or affordances. To clarify this point, we here investigate neural responses when monkeys observed two with similar features contextual information, such as evoked type. We demonstrate many respond to about 30% them affordance....
During foveal reaching, the activity of neurons in macaque medial posterior parietal area V6A is modulated by both gaze and arm direction. In present work, we dissociated position reaching targets, studied neural single cells while eyes targets were arranged different spatial configurations (peripheral combinations). Target influenced all stages task, from visual presentation target movement planning, through reach execution holding time. The majority preferred reaches directed toward...
We aimed at understanding the relative contribution of visual information and hand shaping to neuronal activity medial posterior parietal area V6A, a newly added in monkey cortical grasping circuit. Two Macaca fascicularis performed Reach-to-Grasp task dark light, objects different shapes. found that V6A contains Visual cells, activated only during light; Motor neurons, equally Visuomotor differently while light. Visual, Motor, neurons were moderately or highly selective grasping, whereas...
Accumulating evidence supports the view that medial part of posterior parietal cortex (mPPC) is involved in planning reaching, but while plenty studies investigated reaching performed toward different directions, only a few studied depths. Here, we causal role mPPC (putatively, human area V6A-hV6A) encoding depth and direction reaching. Specifically, applied single-pulse transcranial magnetic stimulation (TMS) over left hV6A at time points 15 participants were immediate, visually guided by...
We present the analysis of muon events with all multiplicities collected during 21804 hours operation first LVD tower. The measured depth-angular distribution intensities has been used to obtain normalization factor, A, power index, gamma, primary all-nucleon spectrum and ratio, R_c, prompt flux that pi-mesons - main parameters which determine cosmic ray muons at sea level. value gamma = 2.77 +/- 0.05 (68% C.L.) R_c < 2.0 x 10^-3 (95% have obtained. upper limit favours models charm...