A5091952348- Parkinson's Disease Mechanisms and Treatments
- Rheumatoid Arthritis Research and Therapies
- Autophagy in Disease and Therapy
- Cancer, Hypoxia, and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Alzheimer's disease research and treatments
- Pharmacological Effects of Medicinal Plants
- Essential Oils and Antimicrobial Activity
- High Altitude and Hypoxia
- Microencapsulation and Drying Processes
- Biochemical effects in animals
- Nanocomposite Films for Food Packaging
- Curcumin's Biomedical Applications
- Osteoarthritis Treatment and Mechanisms
University of Salento
2023-2024
Universitat Politècnica de València
2023
La Trobe University
2023
COMSATS University Islamabad
2023
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder, primarily associated with dopaminergic neuron depletion in the Substantia Nigra. Current treatment focuses on compensating for dopamine (DA) deficiency, but blood–brain barrier (BBB) poses challenges effective drug delivery. Using differentiated SH-SY5Y cells, we investigated co-administration of DA and antioxidant Grape Seed Extract (GSE) to study cytobiocompability, cytoprotection against neurotoxin Rotenone, their...
Serum samples from eight participants during the XV winter-over at Concordia base (Antarctic expedition) collected defined time points, including predeparture, constituted key substrates for a specific metabolomics study. To ascertain acute changes and chronic adaptation to hypoxia, metabolic profiles of serum were analyzed using NMR spectroscopy, with principal components analysis (PCA) followed by partial least squares orthogonal discriminant analyses (PLS-DA OPLS-DA) used as supervised...
Nature abounds in self-assembling systems that include cell membranes, actin fibres and the flagellum rotor.Nature inspired design attempts to learn from organizing principles of these structures while introducing novel molecular designs.It is highly desirable develop a versatile, small molecule based system incorporates universal self-assembly motif allows seamsless spontaneous assembly functionally different molecules.This concept often described as LEGO system.Here substituted oligoamide...