A5103067322- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Medical Imaging Techniques and Applications
- Nuclear physics research studies
- Radioactive contamination and transfer
- Radiopharmaceutical Chemistry and Applications
- Nuclear and radioactivity studies
- Radiation Detection and Scintillator Technologies
- Nuclear reactor physics and engineering
- Radiation Therapy and Dosimetry
- Radioactivity and Radon Measurements
- Cancer therapeutics and mechanisms
- Medical Imaging and Pathology Studies
- Quantum Chromodynamics and Particle Interactions
- Insect and Pesticide Research
- Muon and positron interactions and applications
- Advanced NMR Techniques and Applications
- Advanced MRI Techniques and Applications
- Fusion materials and technologies
- Atomic and Subatomic Physics Research
- Nuclear Materials and Properties
- Diagnosis and treatment of tuberculosis
- Advanced Radiotherapy Techniques
- Advanced X-ray Imaging Techniques
- Crystallography and Radiation Phenomena
Osaka University
2007-2025
Otsuka (Japan)
2016-2020
Osaka International Cancer Institute
2020
Japan Atomic Energy Agency
2007-2017
Osaka City General Hospital
2017
Osaka Prefectural Medical Center
2017
Nagasaki University
2004-2010
Aichi Medical University
1994-1995
Kobe City Medical Center General Hospital
1995
University of Fukui
1970
Soil deposition density maps of gamma-ray emitting radioactive nuclides from the Fukushima Dai-ichi Nuclear Power Plant (NPP) accident were constructed on basis results large-scale soil sampling. In total 10,915 samples collected at 2168 locations. Gamma rays emitted measured by Ge detectors and analyzed using a reliable unified method. The determined radioactivity was corrected to that June 14, 2011 considering intrinsic decay constant each nuclide. Finally created for 134Cs, 137Cs, 131I,...
Spatial distributions and temporal changes of radioactive fallout released by the Fukushima Dai-ichi Nuclear Power Plant accident have been investigated two campaigns with three measurement schedules. The inventories (activities per unit area) radionuclides deposited onto ground soil were measured using portable gamma-ray spectrometers at nearly 1000 locations (at most) campaign. Distribution maps 134Cs, 137Cs, 110mAg as March, September, December 2012 constructed. No apparent change...
There is an urgent need for new, potent antituberculosis (anti-TB) drugs with novel mechanisms of action that can be included in new regimens to shorten the treatment period TB. After screening a library carbostyrils, we optimized 3,4-dihydrocarbostyril derivatives and identified OPC-167832 as having activity. The MICs compound
The cluster structures of the excited states in $^{11}$B are studied by analyzing isoscalar monopole and quadrupole strengths $^{11}$B($d$,$d'$) reaction at $E_d=200$ MeV. excitation compared with predictions shell-model antisymmetrized molecular-dynamics (AMD) calculations. It is found that large strength for $3/2^-_3$ state $E_x=8.56$ MeV well described AMD calculation an evidence a developed $2\alpha+t$ structure.
ABSTRACT The increasing global burden of multidrug-resistant tuberculosis (MDR-TB) requires reliable drug susceptibility testing that accurately characterizes and resistance pathogenic bacteria to effectively treat patients with this deadly disease. Delamanid is an anti-TB agent first approved in the European Union 2014 for treatment pulmonary MDR-TB adults. Using agar proportion method, delamanid MIC was determined 460 isolates: 316 from enrolled a phase 2 clinical trial, 76 two early...
ABSTRACT Tuberculosis (TB) treatment is long and requires multiple drugs, likely due to various phenotypes of TB bacilli with variable drug susceptibilities. Drugs broad activity are urgently needed. This study aimed evaluate delamanid's against growing or dormant in vitro as well vivo . Cultures Mycobacterium bovis BCG Tokyo under aerobic anaerobic conditions were used the delamanid bacilli, respectively. Delamanid exhibited significant bactericidal replicating at above concentrations 0.016...
The incompressibility of infinite nuclear matter (𝐾∞) is a parameter in the description equation state that governs energy cost associated with density oscillations near saturation density. most direct experimental method for studying this property to probe isoscalar giant monopole resonance (ISGMR) finite nuclei. This paper explores use 6Li as study ISGMR several stable nuclei: 58Ni, 90Zr, 116Sn, and 208Pb, complementary using inelastic scattering 𝛼 particles, which has been used great...
Delamanid (DLM), a nitro-dihydroimidazooxazole derivative currently approved for pulmonary multidrug-resistant tuberculosis (TB) therapy, is prodrug activated by mycobacterial 7,8-didemethyl-8-hydroxy 5-deazaflavin electron transfer coenzyme (F 420 )-dependent nitroreductase (Ddn). Despite inhibiting the biosynthesis of subclass mycolic acids, active DLM metabolite remained unknown. Comparative liquid chromatography-mass spectrometry (LC-MS) analysis metabolites revealed covalent binding...
A 69-year-old man had experienced right chest pain for several months. Chest computed tomography (CT) showed a upper lobe lung tumor and swelling of multiple mediastinal hilar lymph node. Three punctures to 4R nodes two 11i were performed, using endobronchial ultrasonography. Thirty days after punctures, he was admitted with appetite loss general fatigue. CT supposed the evidence mediastinitis pericarditis. Despite antibiotics, cardiac tamponade developed on third hospital day. Pericardial...
The alpha inelastic scattering from 24Mg was measured to obtain the isoscalar natural-parity excitation strengths and search for α-condensed states. multipole decomposition analysis cross sections performed. strength distributions ΔL = 0ߝ3 were successfully obtained possible candidates states around 16O core found.
Angular distributions of the elastic and inelastic deuteron-nucleus scattering off $^{24}$Mg, $^{28}$Si, $^{58}$Ni, $^{90}$Zr, $^{116}$Sn, $^{208}$Pb have been measured at a beam energy 98 MeV/nucleon, with goal constraining deuteron optical potential in this kinematical regime, to extract reduced transition probabilities for ground-state transitions low-lying excited states these nuclei. Two models were used analysis $(d,d)$ $(d,d')$ data within model distorted-wave Born approximation:...