- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Urinary Tract Infections Management
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Neonatal and Maternal Infections
- Sepsis Diagnosis and Treatment
- Influenza Virus Research Studies
- Antimicrobial Resistance in Staphylococcus
- Surgical site infection prevention
- Legionella and Acanthamoeba research
- Epilepsy research and treatment
- Neonatal Respiratory Health Research
- COVID-19 and healthcare impacts
- Bacterial Identification and Susceptibility Testing
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Psychological Well-being and Life Satisfaction
- Central Venous Catheters and Hemodialysis
- Optimism, Hope, and Well-being
- Vibrio bacteria research studies
- Pelvic floor disorders treatments
- Teratomas and Epidermoid Cysts
Clinical Centre of Kragujevac
2013-2023
Kliničko Bolnički Centar Zvezdara
2007
Institute of Endocrinology
1979
Importance Staphylococcus aureus surgical site infections (SSIs) and bloodstream (BSIs) are important complications of procedures for which prevention remains suboptimal. Contemporary data on the incidence etiologic factors these needed to support development improved preventive strategies. Objectives To assess occurrence postoperative S SSIs BSIs quantify its association with patient-related contextual factors. Design, Setting, Participants This multicenter cohort study assessed patients at...
Hospital-acquired pneumonia (HAP) and ventilator-associated (VAP) are the most common hospital infections with highest prevalence in intensive care units (ICU). The aim of this study was to investigate bacterial pathogens isolated from ICU patients HAP/VAP reveal their susceptibility rates order establish a basis for empirical antibiotic therapy. Prospective cohort conducted central Clinical Centre Kragujevac, Serbia, January 2009 December 2015, enrolling 620 documented HAP (38.2%) or VAP...
Studies suggest that the incidence of coinfections in patients with coronavirus disease 2019 (COVID-19) is low, but a large number receive antimicrobials during hospitalisation. This may fuel rise antimicrobial resistance (AMR). We conducted multicentre point-prevalence survey seven tertiary university hospitals (in medical wards and intensive care units) Croatia, Italy, Serbia Slovenia. Of 988 COVID-19 patients, 521 were receiving antibiotics and/or antifungals (52.7%; range across...
Acinetobacter baumannii is one of major causative agents severe, life-threatening hospital infections (HIs), especially in intensive care units (ICUs). Our aim was to discover the risk factors associated with emergence HIs caused by carbapenem-resistant (CRAB), as well those death patients who suffer from such infections.A prospective cohort study conducted over a five-year period medical-surgical ICU Clinical Centre Kragujevac, Serbia. The group comprised had CRAB, while control infected...
Introduction: Hospital infections (HIs), which are frequently associated with hospital treatment, increase morbidity, mortality and treatment costs. The aim of this study was to establish the incidence HIs in a neurological intensive care unit (nICU), determine most prevalent causative agents risk factors for HIs. Methodology: A cross-sectional nested case-control design conducted between 1 July 2009 30 June 2010 at an 18-bed Clinical Center Kragujevac, Serbia. Results: In total, 537...
Pseudomonas aeruginosa (PA) is a globally recognized cause of healthcare-associated infections (HAIs). The aim our cross-sectional study, conducted in Serbian tertiary care hospital, was to investigate clinical characteristics HAIs caused by the PA, prevalence various drug-resistant phenotypes this pathogen, and risk factors for their occurrence. Prolonged ICU stay previous carbapenem administration were independent carbapenem-resistant while multidrug-resistant PA more frequent patients...
Ageism is stereotyping and prejudice against individuals or groups because of their age. Robert Butler first used it in 1969, to express a systematic discrimination elderly people. Available data appears confirm that attitudes children the old age differ from adults. The study population consisted 162 subjects (56 school children, 48 nurses 58 patients). Each subject survey was asked respond following three questions: Question #1: "Is unattractive?"; #2: "How an man?"; #3: "What should you...
Abstract Background The independent effects of extranasal-only carriage, carriage at multiple bodily sites, or the bacterial load colonizing Staphylococcus aureus (SA) on risk developing SA surgical site infections and postoperative bloodstream (SA SSI/BSIs) are unclear. We aimed to quantify these in this large prospective cohort study. Methods Surgical patients aged 18 years older were screened for nose, throat, perineum within 30 days before surgery. carriers noncarriers enrolled a study...
The alarming spread of antibiotic-resistant bacteria causing healthcare-associated infections has been extensively reported in recent medical literature.To compare trends antimicrobial consumption and development resistance among isolates Acinetobacter spp. Pseudomonas aeruginosa that cause hospital infections.Cross-sectional study.A study was conducted a tertiary healthcare institution central Serbia, during the 7-year period between January 2009 December 2015. incidence rate caused by or...
Restless leg syndrome (RLS) affects the quality of life and survival in patients on hemodialysis (HD). The aim this study was to determine characteristics parameters HD with RLS. This a non-randomized clinical involving 204 HD, whom 71 were female 133 male. Symptoms RLS defined as positive responses four questions comprising criteria We recorded outcome treatment, biochemical analyses, demographic, sexual, anthropometric all patients. Patients who completed had significantly higher body mass...
Introduction. Pneumonia is the most frequent nosocomial infection in intensive care units. The reported frequency varies with definition, type of hospital or units and population patients. incidence ranges from 6.8-27%. Objective. objective this study was to determine frequency, risk factors mortality pneumonia Methods. We analyzed retrospectively prospectively collected data 180 patients central nervous system infections who needed stay unit for more than 48 hours. This conducted 2003 2009...
Abstract Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has become a major threat to patients in hospitals, increasing mortality, length of stay and costs. The aim this study was discover risk factors for the development hospital infections (HIs) caused by CR-Kp. A prospective cohort conducted Medical-Surgical Intensive Care Unit Clinical Centre Kragujevac, Serbia, from January 1, 2011, December 31, 2015. “cases” were with HIs CR-Kp, while “controls” infected carbapenem-sensitive...
Objective. Healthcare-associated infections (HAIs) represent a major challenge to healthcare systems because they lead increased morbidity, prolonged hospitalization with uncertain outcomes, and treatment costs. The aim of this study is assess the situation regarding HAIs in tertiary level health care institution. Methods. HAI point prevalence was conducted at University Clinical Center Kragujevac (Serbia) during November 2022 within national study. According method European for Disease...
Introduction. Pseudomonas aeruginosa is a common cause of serious infections in hospitalized patients and associated with high rates hospital morbidity mortality. Objective. The aim this study was to identify the risk factors nosocomial caused by piperacillin?tazobactam? resistant P. (PT?RPA). Methods. A case?control conducted Clinical Centre Kragujevac from January 2010 December 2011. Results. In observed period, 79 (38.16%) had PT? RPA infections, while 128 (61.84%)...
Healthcare-acquired urinary tract infections (HAUTI) make up to 40% of all healthcareacquired and contribute significantly hospital morbidity, mortality, overall cost treatment.The aim our study was investigate possible risk factors for development HAUTI caused by multi-drug resistant pathogens.The prospective case-control in a large tertiary-care conducted during five-year period. The cases were patients with (MDR) pathogens, the controls non-MDR pathogens.There 562 (62.6%) MDR isolates 336...
Introduction. Urinary tract infections are the most frequent hospital and account for about 40% of total infections. The main risk factor their development is use catheters. Objective. Assessment basic epidemiological etiological characteristics nosocomial urinary (NUTIs) investigation differences in factors among patients with NUTIs without catheter. Methods. study comprised treated chosen units/ Clinical Center Kragujevac, whom NUTI was registered during 2009. Differences between...
Introduction. Acute respiratory distress syndrome (ARDS) is a significant complication in patients with type A influenza (H1N1) due to the severity of disease and adverse outcome. Objective. The aim study was identify risk factors for development ARDS outcome ARDS. Methods. research conducted as case series study, included admitted at Clinical Center Kragujevac during 2009 2010 flu season. Data were obtained from patients? medical records, inclusion criteria having been determined accordance...
What is known and objective Regular surveillance of antimicrobial resistance an important component multifaceted interventions directed at the problem with bacteria causing healthcare-associated infections (HAIs) in intensive care units (ICUs). Our aim was to analyse consumption among isolates Pseudomonas aeruginosa Acinetobacter spp. HAIs, before after introduction mandatory reporting patterns prescribers. Methods A retrospective observational study conducted between January 2011 December...
In children, the incidence of Legionnaires’ disease (LD) is unknown, hospital-acquired LD associated with clinical risk factors and environmental risk, children cell-mediated immune deficiency are at high infection. Both newborns were born in same delivery room; stayed hospital room where they cared for, bathed, breastfed; male; on time, normal birth weight, Apgar score birth; survived this severe infection (L. pneumophila, serogroup 2-15) but different courses. neonate 1, bleeding brain,...
Urinary tract infections (UTIs) are common problems in women, and important reason for visiting primary care physicians, resulting substantial financial burden to community. The aim of this study was determine the resistance rates E. coli commonly prescribed antimicrobial drugs community-acquired UTIs women establish association between age antibiotics among isolates from urine.The designed as a retrospective cross-sectional during 5-years period. It conducted on sample urinary taken with...