A5010746021- Musculoskeletal pain and rehabilitation
- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Health Systems, Economic Evaluations, Quality of Life
- Pregnancy and Medication Impact
- Psoriasis: Treatment and Pathogenesis
- Spondyloarthritis Studies and Treatments
- Chronic Lymphocytic Leukemia Research
- Hip disorders and treatments
- Bone and Joint Diseases
- Lymphoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Stroke Rehabilitation and Recovery
- Reproductive System and Pregnancy
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pediatric health and respiratory diseases
- Proteoglycans and glycosaminoglycans research
- Lower Extremity Biomechanics and Pathologies
- Hidradenitis Suppurativa and Treatments
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Adipokines, Inflammation, and Metabolic Diseases
- Microscopic Colitis
- Spine and Intervertebral Disc Pathology
Aarhus University Hospital
2009-2024
Aarhus University
2017-2022
Regionshospitalet Silkeborg
2015
To test the effect of patient-reported outcome (PRO)-based tele-health followup for tight control disease activity in patients with rheumatoid arthritis (RA), and differences between performed by rheumatologists or rheumatology nurses.A total 294 were randomized (1:1:1) to either PRO-based carried out a nurse (PRO-TN) rheumatologist (PRO-TR), conventional outpatient physicians. The primary was change Disease Activity Score 28 joints (DAS28) after week 52. Secondary outcomes physical...
Abstract Objective To evaluate and compare benefits harms of three biological treatments with different modes action versus active conventional treatment in patients early rheumatoid arthritis. Design Investigator initiated, randomised, open label, blinded assessor, multiarm, phase IV study. Setting Twenty nine rheumatology departments Sweden, Denmark, Norway, Finland, the Netherlands, Iceland between 2012 2018. Participants Patients aged 18 years older naive arthritis, symptom duration less...
Objective. Rheumatoid arthritis (RA) is a systemic chronic inflammatory joint disease, whereas osteoarthritis (OA) local disease with low-level activity. The pathogenic role of the adipocytokine adiponectin largely unknown in these diseases. We hypothesized (1) that plasma concentrations differ healthy controls and patients early disease-modifying antirheumatic drug (DMARD)-naive RA, OA; (2) changes are observed during methotrexate (MTX) treatment RA; (3) correlates to activity measures RA....
Objective Bone formation is a hallmark of osteoarthritis (OA). It has been speculated that bone may occur because ossification at the bone-cartilage unit, is, directly involving calcified cartilage (CC). This study aimed to investigate thickness CC and subchondral (SCB) in relation severity overlying articular (AC) degeneration. Design We investigated femoral heads from 20 patients with OA 15 healthy subjects design-based stereology using systematic uniform random sampling entire joint...
Objective: To compare the effectiveness of an integrated rehabilitation programme with existing in patients chronic low back pain. Design: A single-centre, pragmatic, two-arm parallel, randomized controlled trial (1:1 ratio). Setting: rheumatology inpatient centre Denmark. Subjects: total 165 adults (aged ⩾ 18 years) Interventions: An comprising alternation three weeks stay and 12 home-based activities was compared four stay. Main measures: Patient-reported outcomes were collected at...
Introduction Immune-mediated inflammatory diseases (IMIDs) are associated with reduced health-related quality of life (HRQol), increased risk somatic and psychiatric comorbidities socioeconomic status. Individuals one IMID have an for developing other IMIDs. The unmet needs in the care patients IMIDs may result from a lack patient-centricity usual monodisciplinary siloed approach to these diseases. advantages novel interdisciplinary clinics towards traditional therapeutic not been...
Objective:To justify and describe an integrated rehabilitation programme for patients with chronic low back pain prior to evaluation in a randomized controlled trial. Method:The Template Intervention Description Replication (TIDieR) checklist was used as structural framework the description of programme. As part description, Medical Research Council guidance, ‘Developing evaluating complex interventions’, description:The adopts participatory biopsychosocial approach integrating inpatient...
Objective: To compare the long-term effectiveness of an integrated rehabilitation programme with existing programme, in terms back-specific disability, patients chronic low back pain. Design: A single-centre, pragmatic, two-arm parallel, randomised controlled trial. Setting: rheumatology centre Denmark. Subjects: total 165 adults (aged ⩾ 18 years) Interventions: An (a pre-admission day, two weeks at home, inpatient followed by home-based activities, plus 2-day booster sessions, and six-month...
Over the past decades new international guidelines recommend that pregnant Systemic lupus erythematosus (SLE) patients are monitored closely in a multi-professional team throughout pregnancy. The importance of low disease activity before pregnancy and continued treatment during has been established. However, there is still high risk adverse outcome (APO).The APO Danish SLE cohort was evaluated compared with results previous study from same centre referral area.This retrospective used local...
Objectives Screening tools are needed to help identify psoriatic arthritis in patients with psoriasis. The Psoriatic UnclutteRed screening Evaluation (PURE-4) questionnaire was developed for this purpose and has been shown perform very well. aim of study translate culturally adapt the PURE-4 scale into Danish language.
Women with chronic rheumatic disease (CRD) are at greater risk of foetal growth restriction than their healthy peers. T2*-weighted magnetic resonance imaging placenta (T2*P-MRI) is superior to conventional ultrasonography in predicting birth weight and works as a proxy metabolic mirror the placental function. We aimed compare T2*P-MRI pregnant women CRD controls. In addition, we investigate correlation between weight.
Abstract Objectives The aim of this study was to identify prognostic variables at baseline associated with being responding favorably multidisciplinary rehabilitation in patients chronic low back pain (CLBP). Methods A responder analysis conducted based on data from a randomized controlled trial 26-week follow-up including 165 CLBP treated Danish center. Patients were dichotomized into responders and non-responders the outcome minimal clinically important difference six points Oswestry...
Patients with chronic inflammatory diseases (CIDs) may encounter challenges in their family planning journey. Here, we report on the access to and pregnancy (FPP) information concerns among patients Denmark CIDs. aged 18–50 years CIDs participated an online survey. were recruited through patient advocacy groups asked diagnosis, related FPP perceptions of information. Descriptive statistics applied. Of eligible respondents, 368 had rheumatological diagnoses (rheumatoid arthritis, psoriatic...
<b>Introduction:</b> Interstitial lung disease (ILD) is a serious complication to rheumatoid arthritis (RA) and increases mortality. The frequency of interstitial among patients with early insufficiently studied. <b>Objectives:</b> aim this study was characterize the ILD newly diagnosed RA in an inception cohort. <b>Methods:</b> included DMARD naive consecutively according ACR/EULAR criteria 2010. Enrolment took place between October 2009 November 2012. Within first six months after...
Psoriatic arthritis (PsA) is a chronic inflammatory that occurs in large proportion of patients with psoriasis causing pain and impaired quality life. Early recognition treatment are important as PsA may result structural joint damage risk reduced physical function.The aim this study was to determine the suspicion who diagnosed or other rheumatologic conditions following referral from dermatology department. Furthermore, aimed identify clinical patient-reported variables identifying whom...