Llanos Martinez Martinez

ORCID: 0000-0003-3087-1977
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About
Contact & Profiles
Research Areas
  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering
  • Nasolacrimal Duct Obstruction Treatments
  • Retinal Imaging and Analysis
  • Salivary Gland Tumors Diagnosis and Treatment
  • Tissue Engineering and Regenerative Medicine
  • Oral and gingival health research
  • Veterinary Equine Medical Research
  • Anatomy and Medical Technology
  • RNA and protein synthesis mechanisms
  • Pancreatic function and diabetes
  • Neurological Disorders and Treatments
  • Tendon Structure and Treatment
  • Sinusitis and nasal conditions
  • HIV Research and Treatment
  • Innovation and Socioeconomic Development
  • Neurogenesis and neuroplasticity mechanisms
  • Gear and Bearing Dynamics Analysis
  • Single-cell and spatial transcriptomics
  • Ethics and bioethics in healthcare
  • Biomedical Ethics and Regulation
  • Cystic Fibrosis Research Advances
  • Ophthalmology and Eye Disorders
  • Developmental Biology and Gene Regulation

Anna Needs Neuroblastoma Answers
2021

Universidad Católica San Antonio de Murcia
2015-2021

Universidad de Murcia
2008

Human pluripotent stem cell (hPSC)-derived pancreatic β cells are an attractive source for treating diabetes. However, current derivation methods remain inefficient, heterogeneous, and line dependent. To address these issues, we first devised a strategy to efficiently cluster hPSC-derived progenitors into 3D structures. Through systematic study, discovered 10 chemicals that not only retain the in clusters but also enhance their potentiality towards NKX6.1+/INS+ cells. We further...

10.1038/s41467-021-23525-x article EN cc-by Nature Communications 2021-06-07

The advent of cellular reprogramming technology converting somatic cells into induced pluripotent stem (iPSCs) has revolutionized our understandings neurodegenerative diseases that are otherwise hard to access and model. Multiple Sclerosis (MS) is a chronic demyelinating, inflammatory disease central nervous system eventually causing neuronal death accompanied disabilities. Here, we report the generation several relapsing-remitting MS (RRMS) primary progressive (PPMS) iPSC lines from...

10.1016/j.scr.2021.102319 article EN cc-by-nc-nd Stem Cell Research 2021-04-16

Purpose. The objective of the present study is to determine whether success rate in transcanalicular diode laser-assisted dacryocystorhinostomy (TCL DCR) influenced by variant septal deviation (SD). Methods. Patients were divided into two groups: one including operated lacrimal pathways (LP) with no anatomical nasosinusal variants and other group LP SD. This began on January 1, 2008, ended December 31, 2010, at Morales Meseguer Hospital. Variables compared means ANOVA a logistic regression...

10.1155/2016/9573760 article EN cc-by Journal of Ophthalmology 2016-01-01

Introduccion. La enfermedad de Alzheimer (EA) es la primera causa demencia mundial. Cada vez son mas los esfuerzos para lograr una deteccion temprana del deterioro cognitivo y surgen en el panorama cientifico entidades diagnosticas como leve (DCL) las quejas subjetivas memoria (QSM). Debido a ello, aparecen numerosos biomarcadores estudiados conseguir dicho objetivo, entre ellos tomografia coherencia optica. Sujetos metodos. Se ha realizado un estudio que utiliza optica medir grosor macular...

10.33588/rn.6301.2016003 article ES Revista de Neurología 2016-01-01

(Abstracted from Cell 2021;184:2020–2032) Pluripotent stem cells (PSCs) have demonstrated the ability to be used in interspecies organogenesis through blastocyst complementation, opening door for production of large quantities vivo generated human tissue regenerative medicine applications. A critical step this process is PSCs (hPSCs) contribute chimera formation; however, some studies shown that hPSCs little chimeric competency species evolutionarily distant humans (eg, mice and pigs).

10.1097/01.ogx.0000767216.18371.e9 article EN Obstetrical & Gynecological Survey 2021-07-01
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