A5008952780- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Mental Health Research Topics
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Psychosomatic Disorders and Their Treatments
- Child Abuse and Trauma
- Advanced Neuroimaging Techniques and Applications
- Hallucinations in medical conditions
- Neural dynamics and brain function
- Psychiatric care and mental health services
University of Bern
2021-2023
Abstract Paranoia is a frequent and highly distressing experience in psychosis. Models of paranoia suggest limbic circuit pathology. Here, we tested whether resting-state functional connectivity (rs-fc) the was altered schizophrenia patients with current paranoia. We collected MRI scans 165 subjects including 89 spectrum disorders (schizophrenia, schizoaffective disorder, brief psychotic schizophreniform disorder) 76 healthy controls. assessed using Positive And Negative Syndrome Scale...
Abstract Negative symptoms (NS) are a core component of schizophrenia affecting community functioning and quality life. We tested neural correlates NS considering factors consensus subdomains. assessed using the Clinical Assessment Interview for Symptoms Scale Symptoms. Arterial spin labeling was applied to measure resting-state cerebral blood flow (rCBF) in 47 patients 44 healthy controls. Multiple regression analyses calculated relationship between rCBF severity. found an association...
Auditory Verbal Hallucinations (AVH) are highly prevalent in patients with schizophrenia. AVH high emotional content lead to particularly poor functional outcome. Increasing evidence shows that associated alterations structure and function language memory related brain regions. However, neural correlates of remain unclear. In our study (n = 91), we resting state cerebral perfusion content, comparing four groups: 13), without 14), hallucinations 20) healthy controls 44). Patients presented...
Auditory Verbal Hallucinations (AVH) are highly prevalent in patients with schizophrenia. AVH high emotional content lead to particularly poor functional outcome. Increasing evidence shows that associated alterations structure and function language memory related brain regions. However, neural correlates of remain unclear. In our study (n = 91), we resting state cerebral perfusion content, comparing without healthy controls. Patients presented increased within the amygdala ventromedial...
Abstract Background Personal space is the safe area around us causing discomfort when violated by others. Previous research has shown that our need for personal can be shaped previous and current experiences. For instance, childhood maltreatment associated with altered in healthy controls. Additionally, regulation schizophrenia (with being increased patients paranoia). Whether dimensions of delusions are safety behaviour unknown. We therefore aim to test association trauma interpersonal...
Abstract Background Schizophrenia is a disabling disorder with tremendous individual burden, reduced quality of life, leading to intense costs for society. Paranoia central feature schizophrenia. In particular, paranoid experience thought be associated aggressive behaviour, and poor social functional outcome. Since threat sometimes hard detect in the clinical interview, simple bedside test identify patients suffering from was recently proposed: interpersonal distance test. Methods For...