A5076694656- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Schizophrenia research and treatment
- Neural and Behavioral Psychology Studies
- Creativity in Education and Neuroscience
- Mental Health and Psychiatry
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Neural dynamics and brain function
- Birth, Development, and Health
- Neuroscience, Education and Cognitive Function
- Child Abuse and Trauma
- Psychiatric care and mental health services
- Advanced Neuroimaging Techniques and Applications
- Hallucinations in medical conditions
- Stress Responses and Cortisol
- Psychosomatic Disorders and Their Treatments
- Circadian rhythm and melatonin
- Memory and Neural Mechanisms
- Neurotransmitter Receptor Influence on Behavior
University of Bern
2020-2023
Abstract Paranoia is a frequent and highly distressing experience in psychosis. Models of paranoia suggest limbic circuit pathology. Here, we tested whether resting-state functional connectivity (rs-fc) the was altered schizophrenia patients with current paranoia. We collected MRI scans 165 subjects including 89 spectrum disorders (schizophrenia, schizoaffective disorder, brief psychotic schizophreniform disorder) 76 healthy controls. assessed using Positive And Negative Syndrome Scale...
Alcohol use disorder (AUD) is characterized by both impaired inhibitory control and heightened cue reactivity, including enhanced craving drinking urges in response to alcohol-related stimuli. The interaction between these two mechanisms thought be crucial the maintenance of addiction relapse. present study used a newly developed Go/NoGo-task investigate how exposure cues affects neural processing subjects with AUD. Functional magnetic resonance imaging (fMRI) was recorded during performance...
Psychiatric disorders share an excess of seasonal birth in winter and spring, suggesting increase neurodevelopmental risks. Evidence suggests season can serve as a proxy harmful environmental factors. Given that prenatal exposure these factors may trigger pathologic processes the neurodevelopment, they consequently lead to brain volume alterations. Here we tested effects on gray matter transdiagnostic sample patients with schizophrenia depression compared healthy controls (n = 192). We found...
Abstract Negative symptoms (NS) are a core component of schizophrenia affecting community functioning and quality life. We tested neural correlates NS considering factors consensus subdomains. assessed using the Clinical Assessment Interview for Symptoms Scale Symptoms. Arterial spin labeling was applied to measure resting-state cerebral blood flow (rCBF) in 47 patients 44 healthy controls. Multiple regression analyses calculated relationship between rCBF severity. found an association...
Auditory Verbal Hallucinations (AVH) are highly prevalent in patients with schizophrenia. AVH high emotional content lead to particularly poor functional outcome. Increasing evidence shows that associated alterations structure and function language memory related brain regions. However, neural correlates of remain unclear. In our study (n = 91), we resting state cerebral perfusion content, comparing four groups: 13), without 14), hallucinations 20) healthy controls 44). Patients presented...
Auditory Verbal Hallucinations (AVH) are highly prevalent in patients with schizophrenia. AVH high emotional content lead to particularly poor functional outcome. Increasing evidence shows that associated alterations structure and function language memory related brain regions. However, neural correlates of remain unclear. In our study (n = 91), we resting state cerebral perfusion content, comparing without healthy controls. Patients presented increased within the amygdala ventromedial...
Einleitung Trotz Fortschritten in der Behandlung Alkoholabhängigkeit sind die Rückfallraten nach Klinikentlassung hoch. Da eine Rückkehr gewohnte Trinkumgebung häufig zu Rückfällen führt, wird Untersuchung von Umgebungseinflüssen zunehmend als wichtig erachtet. Die Cue-Reaktivität diesem Zusammenhang untersucht. Forschung zeigt vermehrt, dass kontextuelle Einflüsse, wie beispielsweise Umgebung des häufigen Konsums, soziale Situationen/Interaktionen wesentlichen Einfluss auf...
Abstract Background Personal space is the safe area around us causing discomfort when violated by others. Previous research has shown that our need for personal can be shaped previous and current experiences. For instance, childhood maltreatment associated with altered in healthy controls. Additionally, regulation schizophrenia (with being increased patients paranoia). Whether dimensions of delusions are safety behaviour unknown. We therefore aim to test association trauma interpersonal...
Abstract Background Schizophrenia is a disabling disorder with tremendous individual burden, reduced quality of life, leading to intense costs for society. Paranoia central feature schizophrenia. In particular, paranoid experience thought be associated aggressive behaviour, and poor social functional outcome. Since threat sometimes hard detect in the clinical interview, simple bedside test identify patients suffering from was recently proposed: interpersonal distance test. Methods For...
In individuals with alcohol use disorder (AUD), the brain areas underlying cue-induced reactions (e.g., cingulum, striatum, thalamus) and altered activation of these regions have been identified by functional neuroimaging. Neuronal responses to a complex alcohol-related context are yet investigate. To better understand contextual effects as well interplay neural exposure, present study implemented an imagination procedure during magnetic resonance imaging (fMRI).Thirteen patients AUD 13...