A5039251769- Physical Activity and Health
- Cardiovascular and exercise physiology
- Obesity, Physical Activity, Diet
- Body Composition Measurement Techniques
- Nutrition and Health in Aging
- Adipose Tissue and Metabolism
- Cardiovascular Disease and Adiposity
- Behavioral Health and Interventions
- Metabolomics and Mass Spectrometry Studies
- Thermoregulation and physiological responses
- School Health and Nursing Education
- Nutritional Studies and Diet
- Dietary Effects on Health
- Cardiac Health and Mental Health
- Health Promotion and Cardiovascular Prevention
- Eating Disorders and Behaviors
- Impact of Technology on Adolescents
- Optimism, Hope, and Well-being
- Youth Development and Social Support
- Health and Wellbeing Research
- Muscle metabolism and nutrition
- Health and Lifestyle Studies
- Agriculture Sustainability and Environmental Impact
- Childhood Cancer Survivors' Quality of Life
- Higher Education Practises and Engagement
Translational Research Institute for Metabolism and Diabetes
2020-2024
AdventHealth Orlando
2022-2024
Queen's University
2013-2022
University of Alabama at Birmingham
2022
Kingston Health Sciences Centre
2022
Queens University
2019
Abstract Objective The aim of this study was to examine associations ectopic adipose tissue (AT) with skeletal muscle (SM) mitochondrial bioenergetics in older adults. Methods Cross‐sectional data from 829 adults ≥70 years age were used. Abdominal, subcutaneous, and visceral AT thigh fat infiltration (MFI) quantified by magnetic resonance imaging. SM energetics characterized vivo ( 31 P‐magnetic spectroscopy; ATP max ) ex (high‐resolution respirometry maximal oxidative phosphorylation...
ABSTRACT Purpose High-throughput profiling of metabolic status (metabolomics) allows for the assessment small-molecule metabolites that may participate in exercise-induced biochemical pathways and corresponding cardiometabolic risk modification. We sought to describe changes a diverse set plasma metabolite profiles patients undergoing chronic exercise training assess relationship between response exercise. Methods A secondary analysis was performed 216 middle-age abdominally obese men women...
Abstract Background Aging-related disease risk is exacerbated by obesity and physical inactivity. It unclear how weight loss increased activity improve in older adults. We aimed to determine the effects of diet-induced with without exercise on insulin sensitivity, VO2peak, body composition, function obese Methods Physically inactive (68.6 ± 4.5 years) (body mass index 37.4 4.9 kg/m2) adults were randomized health education control (HEC; n = 25); (WL; 31); or (WLEX; 28) for 6 months. Insulin...
Exercise mediates tissue metabolic function through direct and indirect adaptations to acylcarnitine (AC) metabolism, but the exact mechanisms are unclear. We found that circulating medium-chain acylcarnitines (C12-C16) lower in active/endurance trained human subjects compared sedentary controls, this is correlated with elevated cardiorespiratory fitness reduced adiposity. In mice, exercise serum AC increased liver AC, was accompanied by a marked increase expression of genes involved hepatic...
ABSTRACT Purpose This study aimed to determine the magnitude of exercise-induced individual variability for waist circumference (WC) and body weight change after accounting biological measurement error. Determinants response were also considered. Methods Participants (53 ± 7.5 yr) 181 adults (61% women) with abdominal obesity randomized following: control; low-amount, low-intensity exercise (LALI); high-amount, (HALI); or high-intensity (HAHI) 24 wk. Unstructured physical activity was...
Objective To determine the effects of exercise amount (kilocalories per session) and intensity (percent maximal oxygen consumption [% VO 2 peak]) on adipose tissue (AT) skeletal muscle (SM) in adults with abdominal obesity. Methods Participants ( n = 103; 52.7 ± 7.6 years) were randomized to following groups: control; low‐amount, low‐intensity (180 kcal/session [women] 300 [men] at 50% peak); high‐amount, (HALI; 360 600 or high‐intensity (HAHI; 75% peak) for 24 weeks. Activities daily living...
Weight loss induced by decreased energy intake (diet) or exercise generally has favorable effects on insulin sensitivity and cardiometabolic risk. The variation in these responses to diet-induced weight with without exercise, particularly older obese adults, is less clear. objectives of our study were (1) examine the effect variability risk factors (2) explore whether baseline phenotypic characteristics are associated response. Sedentary (BMI 36.3 ± 5.0 kg/m2) adults (68.6 4.7 years)...
ABSTRACT Purpose (1) Determine the effect of exercise amount and intensity on proportion individuals for whom adipose tissue (AT) response is above minimal clinically important difference (MCID); (2) Examine whether meaningful anthropometric changes reflect individual AT responses MCID. Methods Men ( n = 41) women 62) (52.7 ± 7.6 yr) were randomized to control 20); low 24); high 30); 29) treadmill 24 wk. The measured by MRI. 90% confidence intervals each individual’s observed calculated as...
Abdominal obesity and low cardiorespiratory fitness (CRF) are associated with insulin resistance in older adults. Exercise is improvement sensitivity. Whether this association mediated by change CRF and/or abdominal unclear. The current study a secondary analysis of data from randomized controlled trial Kingston, Ontario. Sedentary adults (60–80 years) (N = 80) who completed the exercise 59) or control 21) conditions for 6 months were included. was measured using treadmill test, adipose...
Objective. Physician physical activity (PA) counseling remains low due partly to lack of knowledge, emphasizing the importance providing learning opportunities develop competency, given strong associations between PA and health. This study aimed describe behavior change techniques (BCTs) used in an “Exercise Expo” workshop examine workshop’s effectiveness for improving social cognitions discuss exercise with patients. Methods. Second-year medical students (N = 54; M age ± SD 25.4 2.95 years)...
Objectives: Total, visceral and abdominal subcutaneous adipose tissue (AT) depots have distinct associations with cardiometabolic health; however, the metabolite profiles that characterize each AT depot its reduction following exercise are poorly understood. Our objectives were to (1) assess independent between identified metabolites total, AT; (2) examine whether changes in concentrations mass aerobic associated. Methods: A secondary analysis was performed 103 middle-aged abdominally obese...
(1) Determine the effect of exercise amount and intensity on proportion adipose tissue (AT) responses likely, very unlikely above minimal clinically important difference (MCID); (2) Examine whether meaningful anthropometric changes reflect individual AT MCID.
Efforts to manage obesity through weight loss are often unsuccessful as most adults not able sustain the major changes in behaviour that required maintain long term. We sought determine whether small physical activity and diet prevent gain with overweight obesity.We randomized 320 sedentary or monitoring alone (MA, n = 160) a change approach (SCA, 160). In Phase I (2 yr), MA participants were asked their normal lifestyle SCA counselled make activity, namely suggested increase daily step...
Child and adult obesity continue to be major health concerns in the United States can contribute development of chronic diseases. Culinary medicine, which incorporates teaching kitchens gardens, may a useful strategy for preventing and/or treating obesity-related disease by providing knowledge skills that encourage consumption whole plant-based foods prepared at home. Though emerging research describes benefits culinary medicine-based programming, examples gardens being integrated into...
<ns4:p>This article was migrated. The not marked as recommended. Exercise is Medicine Canada (EIMC) at Queen's University provided physical activity (PA) education to first year Ontario medical student conference attendees. 24 participants (23±2years) completed questionnaires one week prior (online/in-person) and after (online) the conference. theory evidence based content resulted in statistically significant increases EIMC (χ²[1,N=24]=26.32,p<0.001) Canadian PA guideline...
<ns4:p>This article was migrated. The not marked as recommended. Background: Applying the Theory of Planned Behavior, we examined gender differences in physical activity (PA) behavior and social cognitions (SC; i.e., attitudes, perceived behavioral control, intentions subjective norms) among first-year medical students. Methods: In October 2015, students from across Ontario [n=95; 23±2 years (31 males)] completed questionnaires assessing PA levels SC. Results: Men reported greater...
Lifestyle behaviors, including physical activity, may help to mitigate the chronic disease and mental health consequences of shift work in nurses at individual level. The activity levels shift-working factors that predict this population are unclear.
Abstract Objective Examine the association of ectopic adipose tissue (AT) with skeletal muscle (SM) mitochondrial bioenergetics in older adults. Methods Cross-sectional data from 829 adults ≥70 years was used. Total abdominal, subcutaneous, and visceral AT; thigh fat infiltration (MFI) quantified by MRI. SM energetics were characterized using vivo 31 P-MRS (ATP max ) ex high-resolution respirometry (maximal oxidative phosphorylation (OXPHOS)). ActivPal used to measure PA (step count). Linear...
ABSTRACT Purpose This study aimed to examine individual exercise response rates across a range of cardiometabolic variables, cardiorespiratory fitness, and body composition in adults. Methods A retrospective analysis data from three randomized controlled trials was used this study. Participants include those who completed the given trial (control, n = 87; intervention, 251). Anthropometric (weight, mass index, waist circumference), fitness (V̇O 2peak ), MRI-measured total adipose tissue...