Alexios Hadjis

ORCID: 0000-0003-3094-1648
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Cardiac pacing and defibrillation studies
  • Atrial Fibrillation Management and Outcomes
  • Coronary Artery Anomalies
  • Neurological disorders and treatments
  • Advanced MRI Techniques and Applications
  • Cardiovascular Effects of Exercise
  • Cardiac Imaging and Diagnostics
  • Aortic Disease and Treatment Approaches
  • Aortic aneurysm repair treatments
  • Cardiac Valve Diseases and Treatments
  • Venous Thromboembolism Diagnosis and Management

Hôpital du Sacré-Cœur de Montréal
2020-2025

Université de Montréal
2020-2025

University of California, San Francisco
2020-2022

Vita-Salute San Raffaele University
2020-2021

Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2020-2021

Istituti di Ricovero e Cura a Carattere Scientifico
2020

IRCCS Ospedale San Raffaele
2020

McGill University Health Centre
2015-2019

BACKGROUND: Catheter ablation of ventricular arrhythmias, one the most rapidly growing procedures in cardiac electrophysiology, is associated with magnetic resonance imaging–detected brain lesions more than half cases. Although a retrograde aortic approach conventional, modern tools enable entry through transseptal that may avoid embolization debris from arterial system. We sought to test hypothesis puncture would mitigate injury compared approach. METHODS: The TRAVERSE trial (Transseptal...

10.1161/circulationaha.124.071352 article EN Circulation 2025-02-24

Background: The development of multielectrode mapping catheters has expanded the spectrum mappable ventricular tachycardias (VTs). Full diastolic pathway recording been associated with a high rate VT termination during radiofrequency ablation as well noninducibility at study end. However, role on recurrence yet to be clearly elucidated. We aimed explore complete activation recurrence. Methods: Eighty-five consecutive patients who underwent guided by high-density were enrolled. During...

10.1161/circep.120.008651 article EN cc-by Circulation Arrhythmia and Electrophysiology 2020-07-28

Percutaneous subclavian, axillary, and cephalic vein access are all used in conjunction for atrial ventricular lead implantation, though no standard approach cardiac resynchronization therapy (CRT) device implantation has been established. We describe an effective a safe technique implanting three leads via CRT pacemaker and/or defibrillator implantations.A total of 171 consecutive patients undergoing de novo or were included. Cephalic was achieved by dissection direct visualization. If the...

10.1093/europace/euw276 article EN EP Europace 2017-03-17

In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain long-debated mechanisms behind atrial fibrillation (AF) reliably numerically predict its induction sustainment. A key role is played, in this respect, by new way setting parametrization electrophysiological mathematical models based on conduction velocities; these latter are estimated from high-density mapping data, which provide detailed characterization patients' substrate during...

10.3389/fphys.2021.673612 article EN cc-by Frontiers in Physiology 2021-07-08

Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in heart failure with reduced ejection fraction (HFrEF). CRT efficacy is greater left bundle branch block (LBBB). This study aimed to determine if strict LBBB criteria predict an improved QRS duration ventricular (LVEF) response after CRT.HFrEF patients who received a device at single quaternary center were included. Patients divided into three groups based on baseline morphology. Group 1 consisted of LBBB. 2 had...

10.1111/pace.13638 article EN Pacing and Clinical Electrophysiology 2019-02-19

Abstract Background Little is known regarding the characterization of electrical substrate in both atria patients with atrial fibrillation (AF). Methods Eight consecutive undergoing AF ablation (five paroxysmal, three persistent) underwent during sinus rhythm. Mapping left (LA) and right atrium (RA) was performed use HD Grid catheter (Abbott). Bipolar voltage maps were analyzed to search for low areas (LVA), following electrophysiological phenomena assessed: (1) slow conduction corridors,...

10.1111/pace.14490 article EN Pacing and Clinical Electrophysiology 2022-04-11

Atrial fibrillation (AF) ablation is performed worldwide. To attract patients, hospitals frequently have webpages that tout the success of procedure. The information disseminated to public via these has not been systematically reviewed. Our objective was assess accuracy delivered on hospital websites in regard atrial AF ablation.From July 2019 January 2020, we a Google search for all US registered with Medicare see if they had webpage describing ablation. Resulting were abstracted data rates...

10.1111/jce.15606 article EN Journal of Cardiovascular Electrophysiology 2022-06-21

Studies of VT mechanisms are largely based on a 2D portrait reentrant circuits one surface the heart. This oversimplifies 3D circuit that involves depth myocardium. Simultaneous epicardial and endocardial (epi-endo) mapping was shown to facilitate delineation circuits, which is however difficult via invasive mapping.

10.1101/2024.03.13.24304259 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-03-16

The mechanisms of bimorphic ventricular tachycardia (VT) have been studied since the 1980s. Miller et al1 described possible that could explain variable QRS morphologies on surface electrocardiogram (ECG): different expressions same VT circuit due to preferential exit points along a shared isthmus; distinct circuits closely placed; and widely unconnected arrhythmogenic sites. first 2 seem account for most cases seen in clinical practice. Bogun al2 reported isthmus with may up 40% VTs...

10.1016/j.hroo.2022.09.017 article EN cc-by-nc-nd Heart Rhythm O2 2022-09-28

When faced with a patient surviving sudden cardiac death (SCD) following ventricular fibrillation (VF), the electrophysiologist is tasked searching for an identifiable cause of arrhythmia, whether it be structural, electrical, or genetic. Identifying clear not only establishes diagnosis but permits tailored counseling and management. Furthermore, identification modifiable reversible elements may improve prognosis if properly addressed. In most challenging cases, exhaustive careful...

10.1016/j.hrcr.2021.07.011 article EN cc-by-nc-nd HeartRhythm Case Reports 2021-07-31
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