A5101743445- Crystallization and Solubility Studies
- Advancements in Transdermal Drug Delivery
- X-ray Diffraction in Crystallography
- Bee Products Chemical Analysis
- Drug Transport and Resistance Mechanisms
- Essential Oils and Antimicrobial Activity
- Natural Compound Pharmacology Studies
- Advanced Drug Delivery Systems
- Ferroptosis and cancer prognosis
- Glycosylation and Glycoproteins Research
- Global trade and economics
- Quality and Supply Management
- Bioactive Compounds and Antitumor Agents
- Gait Recognition and Analysis
- Pharmacological Effects and Toxicity Studies
- RNA modifications and cancer
- Information Technology Governance and Strategy
- Graphene and Nanomaterials Applications
- International Business and FDI
- Mitochondrial Function and Pathology
- Cholinesterase and Neurodegenerative Diseases
- Advanced biosensing and bioanalysis techniques
- Virtual Reality Applications and Impacts
- Pharmacological Receptor Mechanisms and Effects
- ERP Systems Implementation and Impact
Universidade do Porto
2004-2024
General Electric (France)
2024
Centro Hospitalar Tondela-Viseu
2024
Institute of Mechanical Engineering and Industrial Mangement
2022-2023
Rede de Química e Tecnologia
2013-2022
University of Minho
2021
ISEG - Instituto Superior de Economia e Gestão
2017
Instituto Superior de Gestão
2017
Universidade Nova de Lisboa
2013
Hospitais da Universidade de Coimbra
2012
Este artigo propõe uma reflexão crítica sobre as políticas públicas de saúde no Brasil, considerando, sobretudo, os determinantes sociais e desigualdades que dificultam o acesso efetivo da população aos serviços do Sistema Único Saúde (SUS). Ainda SUS represente um marco civilizatório ao garantir direito à como dever Estado todos, na prática, esse tem sido marcado por profundas assimetrias. Isso porque, além das condições econômicas, fatores raça/cor, território, gênero escolaridade seguem...
Polyhydroxyalkanoate (PHA) production via mixed microbial cultures (MMCs) can potentially decrease process operational costs as compared to conventional pure culture techniques. However, the volumetric productivity of PHA by MMCs must be augmented increase its cost competitiveness. For this purpose, a three‐stage bioreactor system was operated in study, with (i) anaerobic fermentation molasses, (ii) selection, and (iii) accumulation harvesting stages. In stage 2, operation pH control at 8...
Oxidative stress, triggered by UV radiation, is one of the major causes free radical-associated disorders, such as skin cancer. The application natural compounds (NCs) with antioxidant effects can attenuate radicals' accumulation and, therefore, provide a strategy for care and cancer prevention. In this work, three compounds, naringenin, nordihydroguaiaretic acid (NDGA), kaempferol, were encapsulated into nanostructured lipid carriers (NLCs) aiming development formulation cutaneous...
The long lifespan of the world's population has been raising interest in research for new solutions to delay aging process. With aim skin prevention, solid lipid nanoparticles (SLNs) were developed this work encapsulation three lipophilic natural compounds extracted from vine cane-epigallocatechin gallate (EGCG), resveratrol and myricetin. loaded-SLNs proved be stable, maintaining their adequate physicochemical characteristics 30 days. In addition, formulations exhibited high efficiencies...
P-glycoprotein (P-gp) plays a crucial role in the protection of susceptible organs, by significantly decreasing absorption/distribution harmful xenobiotics and, consequently, their toxicity. Therefore, P-gp has been proposed as potential antidotal pathway, when activated and/or induced. Knowing that xanthones are known to interact with P-gp, main goal was study induction or/and activation six new oxygenated (OX 1-6). Furthermore, Caco-2 cells against paraquat cytotoxicity also assessed. The...
In order to perform a critical analysis of the zirconium oxide effects in sulfonated poly(ether ether ketone) (SPEEK) membranes with two sulfonation degrees (SD), 71 and 87%, characterization composite prepared systematic variation inorganic content is proposed. The method involves preparation wide range properties which concern water swelling, chemical thermal stability, methanol permeations and, finally, proton conductivity. A good balance between high conductivity, stability low...
This article reviews the growing body of literature that empirically analyzes impact outward FDI on home country exports. Focusing analysis various types studies and identifying methods used countries analyzed, this study allows us to identify gaps in make suggestions for future research. Future research efforts should focus more disaggregated data, particularly at firm product levels, adopt a multilateral approach, which is essential complete relationship between
P-glycoprotein (P-gp) is an ATP-binding cassette transporter involved in the efflux of numerous compounds that influences pharmacokinetics xenobiotics. It reduces intestinal absorption and exposure target cells to toxicity. Thioxanthones are able induce and/or activate P-gp vitro. Particularly, 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) behaves as a inducer activator The aims this study were: i) perform histological characterization, by testing single high dose TX5 [30 mg/kg,...
Exports and foreign direct investment (FDI) are two alternative markets entry modes. From a theoretical point of view, there arguments which support different relationships between FDI exports: complementary substitution. Most empirical studies, however, have concluded with relationship. Since existing studies at more disaggregated levels focused solely on the manufacturing industry, this paper aims studying relationship home country exports based large sample Portuguese firms, belonging to...
Abstract This work, developed as a case study, propose, describe, and evaluates an implementation of pull system in SME company producing polymeric components for the automotive industry. The production was based on push paradigm, which creates high stock levels lead times. main purpose to develop controlled by Kanbans painting line. To achieve this goal, study demonstrates application relevant lean tools, such as, VSM, SMED, Kanban System, Supermarkets Leveling. Through SMED’s application,...