A5100452757- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Mosquito-borne diseases and control
- Gut microbiota and health
- Viral Infections and Vectors
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Nutrition and Health in Aging
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Viral gastroenteritis research and epidemiology
- Cancer-related molecular mechanisms research
- Bacterial Identification and Susceptibility Testing
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Cancer, Hypoxia, and Metabolism
- Gastrointestinal disorders and treatments
- Renal and related cancers
- Body Composition Measurement Techniques
- Parasitic infections in humans and animals
- Parasitic Diseases Research and Treatment
- Dietary Effects on Health
- Spaceflight effects on biology
- Bone health and treatments
Tianjin Hospital
2024-2025
Jilin Academy of Agricultural Sciences
2025
Peking Union Medical College Hospital
2025
Central South University
2025
Tianjin People's Hospital
2024-2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2025
Wenzhou Medical University
2025
University of Bristol
2024
First People's Hospital of Chongqing
2024
Nanjing Medical University
2022
Background and Aims Ulcerative colitis (UC) has become a global public health concern, is in urgent need of novel therapies. Fecal microbiota transplantation (FMT) targeting gut recently been applied to the treatment UC. Despite its recent successes, it still largely unknown how FMT functionally modulates improves disease. Methods We prospectively collected fecal samples from 40 mice (30 for dextran sulfate sodium (DSS)-induced, 10 controls), followed by Propidium monoazide 16S rRNA gene...
Objective: During the follow-up of patients recovered from coronavirus disease 2019 (COVID-19) in quarantine and observation period, some cured showed positive results again. The recurrent RT-PCR test drew widespread concern. We observed a certain number COVID-19 with results, try to analyze factors that caused phenomenon. Methods: conducted an observational study discharged 6 rehabilitation stations Wuhan, China. All subjects met criteria for hospital discharge were quarantine. Data...
Mung bean (Vigna radiata) plays a significant role in agricultural trade, food processing and utilization, cropping structure adjustment due to its abundant nutritional components, medicine-food homology, capacity for nitrogen fixation, soil improvement. The low yield level is crucial limitation factor the mung industry, while heterosis an efficient path increasing crop yields. flexible utilization of male sterile materials may solve this pressing demand industry. This study identified...
Endometriosis is marked by the ectopic growth, spread, and invasion of endometrial tissue beyond uterus, resulting in recurrent bleeding, pain, reproductive challenges, formation nodules or masses. Despite advancements detection methods like ultrasound laparoscopy, these techniques remain limited low specificity invasiveness, underscoring need for a highly specific, noninvasive vitro diagnostic method. This study investigates potential using menstrual blood as sample endometriosis targeting...
Cirrhosis is an important cause of morbidity and death in patients with chronic liver disease. It can be divided into compensatory decompensated stages. During the decompensation period, complications such as esophageal gastric varices hemorrhage, hepatic encephalopathy, infection, hepatorenal syndrome are often incurred, which has a high mortality rate leverages huge economic burden on society, healthcare resources, individuals. Sarcopenia frailty common cirrhosis. The pathogenesis...
Aim: MTHFD1 was the enzyme providing one-carbon derivatives of tetrahydrofolate. We sought to investigate impact on hepatocellular carcinoma (HCC). Methods: Bioinformatic analysis, western blot and immunohistochemistry were conducted detect expression in HCC. The relationships between prognosis 172 HCCs analyzed by Kaplan–Meier method Cox proportional hazards model. Results: High HCC represented poor (overall survival p = 0.025; time recurrence 0.044). Combining with serum AFP, analysis...
Abstract Background Faecal microbiota transplantation (FMT) is an effective therapy for recurrent Clostridium difficile infections and chronic gastrointestional infections. However, the risks of FMT selection process suitable donors remain insufficiently characterized. The eligibility rate screening, underlying microbial basis, core ethical issues stool are yet to be elucidated in China. Results potential were screened from December 2017 2019 with help online survey, clinical assessments,...
To analyse the epidemiology of coded rotavirus hospitalisations in Australia from 1993 to 2002, with a view understanding pre-vaccination burden severe disease Australia. This study also seeks determine rotavirus-related mortality.Hospitalisation data Australian Institute Health and Welfare for period 1993-2002 were analysed. Rotavirus-related mortality National Mortality Database analysed 1990-2002.There an average 4260 patients hospitalised each year. The majority occurred those under age...
The treatment success rate of drug-resistant (DR) tuberculosis is alarmingly low. Therefore, more effective and less complex regimens are urgently required.
Surveillance for intussusception (IS) has been recommended in countries using rotavirus vaccine, but can be resource intensive. There is little data about the relative severity of vaccine-associated IS compared with other cases. We collected detailed clinical on all cases to evaluate validity ICD coding routinely and case severity.Hospitalizations emergency department presentations coded as infants aged <12 months from July 1, 2007, June 30, 2010, were classified Brighton criteria by note...
Purpose:The utility of the EuroQol Group 5 Dimension (EQ-5D) measuring health-related quality life (HRQoL) has been verified; however, knowledge gaps remain concerning predictive performance in cirrhosis.We aimed to identify optimal threshold for risk stratification and pronounced domain EQ-5D linked inferior outcomes.Patients Methods: The X-tile project was used obtain a threshold, considering composite outcome 1-year all-cause mortality or readmission.A restricted cubic spline (RCS)...
Objectives The study aims to identify the outcome and related factors of unvaccinated patients with end-stage kidney disease during Omicron pandemic. Design A multicentre retrospective undergone maintenance haemodialysis (HD) in China. Setting 6 HD centres Participants total 654 who tested positive for SARS-CoV-2 were ultimately included study. Outcome measures primary outcomes interest adverse outcomes, including hospitalisation due COVID-19 all-cause mortality. Results average age was 57...
It is difficult to diagnose ascites infection early in cirrhotic patients. The present study was create and evaluate a new bioscore combined with PCT, sNFI dCHC the diagnosis of patients.Two hundred fifty-nine consecutive patients were enrolled; which 51 culture-positive spontaneous bacterial peritonitis (culture-positive SBP) 58 culture-negative SBP. efficacy procalcitonin(PCT), c-reactive protein (CRP), white blood cell (WBC), mean fluorescence intensity mature neutrophils(sNFI) difference...
Sierra Leone has one of the highest burdens febrile illnesses in world. As incidence malaria diminishes, a better understanding spectrum etiological agents was important for accurate diagnosis and empirical treatment illness. Blood, nasopharyngeal, fecal specimens were collected from patients serological, molecular detection, microbiologic culture to identify potential pathogens. For this prospective study, 142 enrolled. The prevalence higher children aged 5–15 years old (P = 0.185) adults...
Mass spectrometry imaging investigations of tissues infected with agents that require high-security biocontainment, such as Mycobacterium tuberculosis, have been limited due to incompatible sterilization techniques. Here we describe an on-slide heat method enables mass pharmaceuticals, lipids, and metabolites in tissue samples outside biocontainment. An evaluation different temperatures incubation times determined 100 °C for 1 h was essential sterilize 5 the bacterial burden observed...
The majority of creatures on Earth possess an intrinsic biological clock which situates in the suprachiasmatic nucleus hypothalamus. It produces a circadian rhythm that coincides with Earth’s 24-hour cycle through feedback loop involves both transcription and translation, means regulating metabolism energy homeostasis various peripheral organs, such as liver, it plays vital part. As result, has intricate association maintaining metabolic health. Outer environmental factors like lifestyle...
There is a paucity of data regarding sex-oriented analyses connection between muscle quantity and quality health-related life (HRQoL), taking into account the pathophysiological differences sarcopenia/myosteatosis in males versus females. We sought to investigate associations skeletal index (SMI)-defined sarcopenia intramuscular adipose tissue content (IMAC)-defined myosteatosis EuroQol-5D (EQ-5D)-defined HRQoL patients with decompensated cirrhosis concerning sex disparities.
Background There is ample evidence to suggest that patients infected with SARS-CoV-2 Omicron variant may experience liver dysfunction. However, the impact of pre-infection function on postinfection mortality rates remains inadequately researched.