Dong Zhao

ORCID: 0000-0003-3148-4047
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About
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Research Areas
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Mycorrhizal Fungi and Plant Interactions
  • Plant Pathogens and Fungal Diseases
  • Tryptophan and brain disorders
  • Intracranial Aneurysms: Treatment and Complications
  • Lichen and fungal ecology
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Toxic Organic Pollutants Impact
  • Analytical chemistry methods development
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Mosquito-borne diseases and control
  • Biosensors and Analytical Detection
  • Fungal Biology and Applications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Wastewater Treatment and Nitrogen Removal
  • Viral Infections and Immunology Research
  • Cerebrospinal fluid and hydrocephalus
  • Pharmacological Effects of Natural Compounds
  • Neurological Disease Mechanisms and Treatments
  • Monoclonal and Polyclonal Antibodies Research
  • Virology and Viral Diseases
  • Forensic and Genetic Research
  • Cytomegalovirus and herpesvirus research
  • Tea Polyphenols and Effects

Qinghai University
2024-2025

China University of Political Science and Law
2020-2025

Beijing Luhe Hospital Affiliated to Capital Medical University
2024

University of Jinan
2023-2024

First Affiliated Hospital of Shihezi University Medical College
2014-2024

Xi’an International University
2024

Sinolight (China)
2020-2023

Sinopec (China)
2021-2023

China Light Industry Press (China)
2022-2023

Shihezi University
2012-2022

Heart failure (HF) is usually the end stage of continuum various cardiovascular diseases. However, mechanism underlying progression and development HF remains poorly understood. The sigma-1 receptor (Sigmar1) a non-opioid transmembrane implicated in many diseases, including HF. role Sigmar1 has not been fully elucidated.In this study, we used isoproterenol (ISO) to induce wild-type (WT) knockout (Sigmar1-/-) mice. Multi-omic analysis, microbiomics, metabolomics transcriptomics, was employed...

10.3389/fmicb.2023.1255971 article EN cc-by Frontiers in Microbiology 2023-08-31

Abstract Background The link between gastroesophageal reflux disease (GERD) and essential hypertension (EH) its causal nature remains controversial. Our study examined the connection GERD risk of assessed further whether this correlation has a relationship. Methods First, we utilized National Readmission Database including 14 422 183 participants to conduct an observational study. Dividing population into non-GERD groups, investigated EH using multivariate logistic regression. Next,...

10.1093/postmj/qgad123 article EN Postgraduate Medical Journal 2024-01-14

Huangshui polysaccharides (HSPs) have attracted extensive attention recently for their biological activity and physicochemical property. This research investigated the extraction, structural characterization, prebiotic of three different HSPs (HSP40-0, HSP60-0, HSP80-0) in vitro to reveal scientific support high-value utilization Huangshui. were heteropolysaccharide with diverse structures surface morphologies. Comprehensive analysis was conducted through 16S rRNA gene sequencing metabolite...

10.1021/acs.jafc.3c08658 article EN Journal of Agricultural and Food Chemistry 2024-02-20

Trifluralin (FLL) is extensively used in rapeseed fields the Qinghai-Tibet Plateau (QTP) region. However, degradation kinetics of FLL this area and its impact on environmental microbial communities are not yet known. To investigate patterns ecological benefits FLL, study established a comprehensive method for detecting residues selected efficient degrading bacterial strains. Degradation experiments were conducted two typical soil types QTP, dynamic changes explored. The results indicated...

10.1016/j.heliyon.2025.e41770 article EN cc-by-nc Heliyon 2025-01-01

The objectives of this study are to investigate the effect miR-30e targeting GLIPR-2 on pathological mechanism DN. renal tissues db/db and db/m mice at different age weeks were stained with PAS. qRT-PCR was applied detect expression GLIPR-2, not only in but also tubular epithelial cells (RTECs). By luciferase reporter gene assays, we found 3'-UTR mRNA as a direct target miR-30e. RTECs cultured high glucose divided into blank control, NC, mimics, inhibitors, inhibitor + si-GLIPR-2 groups. MTT...

10.1530/jme-17-0083 article EN Journal of Molecular Endocrinology 2017-07-22

Rapid and sensitive identification of genetically modified organisms (GMOs) is urgent for food safety people health. Herein, a rapid ultrasensitive fluorescence sensing platform developed based on the single-strand DNA-labeled FAM dye (FAM-ssDNA) nanometer-sized Fe-metal–organic framework (Fe-MOF), Fe-MIL-88. Fe-MIL-88 possesses large specific surface area, remarkable preferential combining capacity with ssDNA versus dsDNA, great quenching ability. FAM-ssDNA probes are elaborately designed...

10.1021/acsanm.3c01091 article EN ACS Applied Nano Materials 2023-04-12

Realizing discrimination and detection of organic acids using this to achieve classification Baijiu has great practical significance. Three kinds QDs were selected construct a fluorescent sensor array for detecting discriminating Baijiu.

10.1039/d0ay01454k article EN Analytical Methods 2020-01-01

Two new species of Russula are described from southwestern China based on morphology and ITS1-5.8S-ITS2 rDNA sequence analysis. atroaeruginea (sect. Griseinae ) is characterized by a glabrous dark-green radially yellowish tinged pileus, slightly context, spores ornamented low warts linked fine lines, numerous pileocystidia with crystalline contents blackening in sulfovanillin. sichuanensis , semi-sequestrate taxon closely related to sect. Laricinae forms russuloid secotioid basidiocarps...

10.5248/124.173 article EN cc-by-nc-nd Mycotaxon 2013-10-10

Objectives: Early brain injury (EBI) is central to the pathological progress of subarachnoid hemorrhage (SAH). In this study, we determined if neuritin protects against EBI in rats and discussed role apoptosis pathway mediated by endoplasmic reticulum stress neuroprotective route. Methods: A total 96 male Sprague Dawley were divided into control, sham, SAH + groups. The rat model was induced injection 0.3 mL nonheparinized arterial blood prechiasmatic cistern. Mortality assay, neurological...

10.1080/00207454.2017.1337013 article EN International Journal of Neuroscience 2017-05-31
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