- Mycorrhizal Fungi and Plant Interactions
- Lichen and fungal ecology
- Plant Pathogens and Fungal Diseases
- Fungal Biology and Applications
- T-cell and Retrovirus Studies
- Lymphoma Diagnosis and Treatment
- Yeasts and Rust Fungi Studies
- Distributed and Parallel Computing Systems
- Caveolin-1 and cellular processes
- Cloud Computing and Resource Management
- Cassava research and cyanide
- Parallel Computing and Optimization Techniques
- Marine and coastal plant biology
- Urinary Tract Infections Management
- Big Data and Business Intelligence
- Big Data Technologies and Applications
- Musculoskeletal pain and rehabilitation
- Chromosomal and Genetic Variations
- Information Technology Governance and Strategy
- Soil Mechanics and Vehicle Dynamics
- Immune Cell Function and Interaction
- Agricultural Engineering and Mechanization
- Genetic factors in colorectal cancer
- Smart Agriculture and AI
- Genomics and Phylogenetic Studies
Hebei Agricultural University
2021-2024
Duke University
2005-2024
Ministry of Agriculture and Rural Affairs
2022-2024
Chinese Academy of Tropical Agricultural Sciences
2022-2024
Hospital of Hebei Province
2024
Innovation Team (China)
2023-2024
Chinese Academy of Sciences
2009-2023
Institute of Computing Technology
2001-2023
Shenzhen University
2023
Vision Technology (United States)
2023
We have produced a draft sequence of the rice genome for most widely cultivated subspecies in China, Oryza sativa L. ssp. indica , by whole-genome shotgun sequencing. The was 466 megabases size, with an estimated 46,022 to 55,615 genes. Functional coverage assembled sequences 92.0%. About 42.2% exact 20-nucleotide oligomer repeats, and transposons were intergenic regions between Although 80.6% predicted Arabidopsis thaliana genes had homolog rice, only 49.4% A. . large proportion no...
Abstract The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to Ascomycota. present work provides an overview all validly published, currently used basidiomycete genera date single document. An outline provided, which includes 1928 names, with 1263 synonyms, are distributed 241 families, 68 orders, 18 classes four subphyla. We provide brief notes for each accepted genus including information on classification, number species, type life mode,...
Abstract Hepatosplenic T-cell lymphoma (HSTL) is a rare and lethal lymphoma; the genetic drivers of this disease are unknown. Through whole-exome sequencing 68 HSTLs, we define recurrently mutated driver genes copy-number alterations in disease. Chromatin-modifying genes, including SETD2, INO80, ARID1B, were commonly HSTL, affecting 62% cases. HSTLs manifest frequent mutations STAT5B (31%), STAT3 (9%), PIK3CD for which there currently exist potential targeted therapies. In addition, noted...
Two coding variants of apolipoprotein L1 (APOL1) called G1 and G2 explain much the excess risk kidney disease in African Americans. While various cytotoxic phenotypes have been reported experimental models, proximal mechanism by which cause is poorly understood. Here, we leveraged three models a recently small molecule blocker APOL1 protein, VX-147, to identify upstream G1-induced cytotoxicity. In HEK293 cells, demonstrated that G1-mediated Na+ import/K+ efflux triggered activation G...
Type 1 fimbriated Escherichia coli represents the most common human uropathogen, owing much of its virulence to invasion uroepithelium, which is highly impermeable due preponderance uroplakins and ordered lipid components. We sought elucidate molecular basis for E. bladder epithelium by employing 5637 epithelial cells, we found following: (i) intracellular associated with caveolae raft components; (ii) RNAi reduction caveolin-1 expression inhibited bacterial invasion; (iii) a signaling...
Uropathogenic Escherichia coli invade bladder epithelial cells (BECs) by direct entry into specialized cAMP regulated exocytic compartments. Remarkably, a significant number of these intracellular bacteria are subsequently expelled in nonlytic and piecemeal fashion infected BECs. Here, we report that expulsion E. BECs is initiated the pattern recognition receptor, Toll-like receptor (TLR)4, after activation LPS. Also, reveal caveolin-1, Rab27b, PKA, MyRIP components compartment, they form...
Russula fanjing is proposed here as a new species based on morphological and molecular evidence. The described illustrated with photographs line drawings compared to related species. Morphologically, R. (subgenus Russula, section subsection Russula) characterized by medium-sized basidioma, vivid red pastel areolate pileus, white lamellae occasionally forked near the stipe lamellulae, smooth stipe, basidiospores ornamented strongly amyloid warts ridges interconnected fine lines in an...
Four new species of Russula subsection Sardoninae from northern and southwestern China under coniferous deciduous trees are proposed as R. begonia, photinia, rhodochroa, rufa. Illustrations descriptions gracillima, leucomarginata, roseola, the above four provided based on evidence morphological characters phylogenetic analyses internal transcribed spacer (ITS), well multi-locus mtSSU, nLSU, rpb1, rpb2 tef1-α. The relationships between these allied taxa discussed.
Pseudomonas aeruginosa has the capacity to invade lung epithelial cells by co-opting intrinsic endocytic properties of lipid rafts, which are rich in cholesterol, sphingolipids, and proteins, such as caveolin-1 -2. We compared intratracheal infection wild type caveolin-deficient mice investigate role caveolin proteins pathogenesis pneumonia. Unlike mice, succumb pneumonia, resistant Pseudomonas. observed that invasion is dependent on caveolin-2 but not caveolin-1. Phosphorylation Src family...
The Russula globispora lineage is a morphologically and phylogenetically well-defined group of ectomycorrhizal fungi occurring in various climatic areas. In this study we performed multi-locus phylogenetic based on collections from boreal, alpine arctic habitats Europe Western North America, subalpine the southeast Himalayas subtropical coniferous forests Pakistan. European American are nearly identical probably represent single species named R. dryadicola distributed Alps to Rocky...
Three new species of Russulasection Ingratae, found in Guizhou and Jiangsu Provinces, southern China, are proposed: R.straminella, R.subpectinatoides R.succinea. Photographs, line drawings detailed morphological descriptions for these provided with comparisons against closely-related taxa. Phylogenetic analysis the internal transcribed spacer (ITS) region supported recognition specimens as species. Additionally, R.indocatillus is reported first time from China phylogenetic data Chinese specimens.