Wei Guo

ORCID: 0000-0003-3482-5118
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About
Contact & Profiles
Research Areas
  • Genomics and Phylogenetic Studies
  • Plant Molecular Biology Research
  • Plant Pathogens and Fungal Diseases
  • Trace Elements in Health
  • Plant Stress Responses and Tolerance
  • Diet and metabolism studies
  • Plant Gene Expression Analysis
  • Plant tissue culture and regeneration
  • Hearing, Cochlea, Tinnitus, Genetics
  • Metal complexes synthesis and properties
  • Nuts composition and effects
  • Plant and Fungal Species Descriptions
  • Photosynthetic Processes and Mechanisms
  • Natural product bioactivities and synthesis
  • Neonatal Respiratory Health Research
  • Plant nutrient uptake and metabolism
  • Bacteriophages and microbial interactions
  • Plant biochemistry and biosynthesis
  • Plant Reproductive Biology
  • Epigenetics and DNA Methylation
  • Menopause: Health Impacts and Treatments
  • Transgenic Plants and Applications
  • Plant-Microbe Interactions and Immunity
  • Ion channel regulation and function
  • Magnetic and Electromagnetic Effects

Shandong Academy of Forestry
2019-2025

Hubei University of Medicine
2024

Zhongkai University of Agriculture and Engineering
2014-2024

Shandong First Medical University
2021-2024

Affiliated Hospital of Taishan Medical University
2018-2024

Wannan Medical College
2012-2024

Guizhou University
2022-2024

Hebei Medical University
2023

Xingtai People's Hospital
2023

Ministry of Agriculture and Rural Affairs
2022-2023

We have produced a draft sequence of the rice genome for most widely cultivated subspecies in China, Oryza sativa L. ssp. indica , by whole-genome shotgun sequencing. The was 466 megabases size, with an estimated 46,022 to 55,615 genes. Functional coverage assembled sequences 92.0%. About 42.2% exact 20-nucleotide oligomer repeats, and transposons were intergenic regions between Although 80.6% predicted Arabidopsis thaliana genes had homolog rice, only 49.4% A. . large proportion no...

10.1126/science.1068037 article EN Science 2002-04-05

Net primary productivity (NPP) is a core ecological indicator within terrestrial ecosystems, representing the potential of vegetation growth to offset anthropogenic carbon emissions. Thus, assessing NPP in given region crucial for promoting regional restoration and sustainable development. This study utilized CASA model GEE calculate annual average Shandong Province (2001–2020). Through trend analysis, Moran’s Index, PLS−SEM, spatiotemporal evolution driving factors were explored. The...

10.3390/rs17030488 article EN cc-by Remote Sensing 2025-01-30

Here we report the cloning and functional characterization of a rat novel peptide/histidine transporter (PHT1), which was expressed in brain retina. The cDNA encodes predicted protein 572 amino acid residues with 12 putative membrane-spanning domains. sequence has moderate homology nonspecific peptide found plant. When Xenopus laevis oocytes, PHT1 cRNA induced high affinity proton-dependent histidine transport activity. This process inhibited by dipeptides tripeptides but not free acids such...

10.1074/jbc.272.15.10205 article EN cc-by Journal of Biological Chemistry 1997-04-01

Triadin is a major membrane protein that specifically localized in the junctional sarcoplasmic reticulum of skeletal muscle and thought to play an important role excitation-contraction coupling. In order identify proteins interact with triadin, cytoplasmic luminal domains triadin were expressed as glutathione S-transferase fusion immobilized glutathione-Sepharose form affinity columns. Using these columns, we find binds ryanodine receptor/Ca2+ release channel Ca2+ -binding calsequestrin from...

10.1074/jbc.270.16.9027 article EN cc-by Journal of Biological Chemistry 1995-04-01

We report herein a systematic study on interactions of organometallic ruthenium(II) anticancer complex [(η6-arene)Ru(en)Cl]+ (arene = p-cymene (1) or biphenyl (2), en ethylenediamine) with human transferrin (hTf) and the effects hTf-ligation bioavailability these complexes cisplatin as reference. Incubated 5-fold excess 1, 2, cisplatin, 1 mol diferric hTf (holo-hTf) attached 0.62 1.01 2.14 cisplatin. Mass spectrometry revealed that both ruthenium coordinated to N-donors His242, His273,...

10.1021/ic4002626 article EN Inorganic Chemistry 2013-04-15

Abstract Claims surrounding exceptional longevity are sometimes disputed or dismissed for lack of credible evidence. Here, we present three DNA methylation-based age estimators (epigenetic clocks) verifying claims centenarians. The centenarian clocks were developed based on n = 7039 blood and saliva samples from individuals older than 40, including 184 centenarians, 122 semi-supercentenarians (aged 105 +), 25 supercentenarians 110 +). oldest individual was 115 years old. Our most accurate...

10.1007/s11357-023-00731-7 article EN cc-by GeroScience 2023-03-25

Early-life exposure to toxicants could affect health outcomes in adulthood. We determined the effects of early-life organophosphorus flame-retardant tris (1,3-dichloro-2-propyl) phosphate (TDCIPP) adult zebrafish. Embryos were exposed TDCIPP from early embryogenesis (2 h post-fertilization) 10 days post-fertilization (dpf), and larvae transferred clean water until adulthood (150 dpf). showed accumulation larvae, but returned control levels after 7 depuration. In zebrafish life, vulnerability...

10.1016/j.envint.2019.105293 article EN cc-by-nc-nd Environment International 2019-11-12

ABSTRACT Lignin is a major component of plant cell walls and essential for growth development. biosynthesis controlled by hierarchical regulatory network involving multiple transcription factors. In this study, we showed that the gene encoding an APETALA 2/ethylene‐responsive element binding factor (AP2/ERF) factor, PagERF81 , from poplar 84 K ( Populus alba × P. glandulosa ) highly expressed in expanding secondary xylem cells. Two independent homozygous Pagerf81 mutant lines created...

10.1111/jipb.13453 article EN Journal of Integrative Plant Biology 2023-01-17

Changes in gene expression occur during cold acclimation a wide variety of plant species. Here we show that number the polypeptides encoded by cold-regulated (cor) genes Arabidopsis thaliana L. (Heyn) and wheat share unusual biochemical property they remain soluble upon boiling aqueous solution. Further, cDNA cloning conjunction with Southern Northern analyses indicate has cor is related to cor47, encoding 47 kilodalton ;boiling-stable' COR polypeptide. We suggest it likely boiling-stable...

10.1104/pp.94.3.1078 article EN PLANT PHYSIOLOGY 1990-11-01

Triadin is an intrinsic membrane protein first identified in the skeletal muscle junctional sarcoplasmic reticulum and considered to play important role excitation-contraction coupling. Using polyclonal antibodies triadin, we have characterized three isoforms rabbit cardiac muscle. The cDNAs encoding these of triadin been isolated by reverse transcription-polymerase chain reaction cDNA library screening. deduced amino acid sequences show that proteins are identical their N-terminal...

10.1074/jbc.271.1.458 article EN cc-by Journal of Biological Chemistry 1996-01-01

Abstract Static magnetic field (SMF) plays important roles in biological processes of many living organisms. In plants, however, significance SMF and molecular mechanisms underlying action remain largely unknown. To address these questions, we treated Arabidopsis young seedlings with different intensities directions. Magnetic direction from the north to south pole was adjusted parallel (N0) with, opposite (N180) perpendicular gravity vector. We discovered that root growth is significantly...

10.1038/s41598-019-50970-y article EN cc-by Scientific Reports 2019-10-07

Zinc deficiency could lead to a dynamic variation in gut microbial composition and function animals. However, how zinc affects the microbiome school-age children remains unclear. The purpose of this study was profile shifts with deficiency, determine whether such are associated dietary intake. A survey, anthropometric measurements, serum tests were performed on 177 children, 67 selected explore community using amplicon sequencing. School-age suffered from poor diversity insufficient food...

10.3390/nu14142895 article EN Nutrients 2022-07-14

The mechanically activated PIEZO1 ion channel is genetically linked to numerous physiological and pathophysiological processes. For example, deleting in mice leads defective lymphatic vessel development, while nonsense mutations humans are associated with autosomal recessive generalized dysplasia (GLD) non-immune hydrops fetalis. However, it remains unclear whether PIEZO1-dependent biological processes directly mediated by its intrinsic mechanosensitivity. Here we identified a human fetal...

10.1101/2025.02.18.638930 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-02-21

Leaf variegation provides a valuable model for elucidating the molecular mechanisms that underlie chloroplast biogenesis, including both development and division. While there has been notable advancement in comprehending role of Arabidopsis Yellow Variegated2 ( VAR2 ), which encodes AtFtsH2 subunit thylakoid FtsH metalloprotease complex, exact mechanism governing leaf formation remains elusive. In this study, time-course microscopy analyses number per cell from first pair revealed most var2...

10.1101/2025.04.06.647415 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2025-04-06

<title>Abstract</title> The Gayal (<italic>Bos frontalis</italic>) is a rare and endangeredsemi-domesticated cattle species with unique genetic background physiological characteristics. These traits are like those of yaks lived on the Qinghai-Tibet Plateau, such as thicker myocardial connective tissue abundant vascular distribution. genes carried in its genome, including candidate related to immunity, meat quality, reproduction, further highlight biological value. However, due small...

10.21203/rs.3.rs-6263934/v1 preprint EN 2025-04-24

Cu(I) binding promotes the platination of Atox1, although cisplatin binds to copper coordination sites. In addition, enhances competition Atox1 with DTT in reaction cisplatin. These results indicate that cuprous ions could regulate cellular trafficking

10.1039/c3cc45905e article EN Chemical Communications 2013-01-01
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