A5006089698- Advanced Radiotherapy Techniques
- Advances in Oncology and Radiotherapy
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Cancer Genomics and Diagnostics
- Innovative Teaching Methods
- Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Oral health in cancer treatment
- Colorectal and Anal Carcinomas
- Radiation Effects in Electronics
- Radiation Detection and Scintillator Technologies
- Pancreatic and Hepatic Oncology Research
- Glioma Diagnosis and Treatment
- Boron Compounds in Chemistry
- Effects of Radiation Exposure
- Cerebral Venous Sinus Thrombosis
- Breast Cancer Treatment Studies
- COVID-19 and Mental Health
- Neurofibromatosis and Schwannoma Cases
Kangbuk Samsung Hospital
2021-2025
Sungkyunkwan University
2021-2025
Yonsei University
2017-2022
Eulji University
2021
Gangnam Severance Hospital
2021
Samsung Medical Center
2021
Ulsan College
2019
University of Ulsan
2019
Abstract The efficacy of radiotherapy is often limited by insufficient radiosensitization and tumor radioresistance. This study reports a dual‐functional hafnium oxide nanoplatform that combines high‐Z with Bcl‐2 gene silencing for enhanced cancer radiotherapy. developed surface modification nanoparticles polyethyleneimine, enabling efficient siRNA delivery while maintaining inherent radiosensitizing properties. Comprehensive physicochemical characterization confirmed the successful stable...
Purpose Although stereotactic ablative body radiotherapy (SABR) is widely used therapeutic technique, predictive factors of radiation pneumonitis (RP) after SABR remain undefined. We aimed to investigate the affecting RP in patients with primary or metastatic lung tumors who received SABR. Materials and Methods From 2012 2015, we reviewed 59 72 treated SABR, performed analyses clinical dosimetric variables related symptomatic RP. was delivered as 45–60 Gy 3–4 fractions, which were over 100...
Although there have been many attempts to increase the therapeutic ratio of radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma (MALToma), only a few planning studies reported efficacy modern technique till date. Therefore, we performed dosimetric comparison among 3-dimensional conformal (3D-CRT) and intensity-modulated (IMRT) plans, using deep-inspiration breath hold (DIBH) or free-breathing (FB) techniques, determine most optimal plan MALToma. We evaluated 9 patients with...
Preclinical data indicate that response to radiotherapy (RT) depends on DNA damage repair. In this study, we investigated the role of mutations in genes related repair treatment outcome after RT.Patients with solid tumor who participated next generation sequencing panel screening using biopsied tissue between October 2013 and February 2019 were reviewed 97 patients received RT included study. Best cumulative local recurrence rate (LRR) compared according absence or presence missense,...
Abstract Background The COVID-19 pandemic has stripped many medical students worldwide of their right to quality education. In response, we developed hybrid courses involving aspects both online and in-person teaching for radiation oncology student clerkship. Methods We entitled customize own rotation schedule using Google Forms a flipped learning class, which consisted at least one video clip on basic knowledge per day (yonsei-radonc.com). Students were instructed watch videos before the...
We aimed to compare the outcomes of adjuvant radiotherapy (ART) and surveillance in patients with grade 2 meningiomas (MNG2) who underwent surgical resection. Data from four hospitals, which aged ≥18 years Simpson 1-4 resection for newly diagnosed MNG2 between 1998 2018, were examined this multicenter retrospective cohort study. Patients receiving ART conventional fractionation compared those undergoing surveillance. Progression-free survival (PFS), progression/recurrence (P/R) evaluated....
Abstract Background We investigated dental implant outcomes in patients who had previously received radiotherapy (RT) for head and neck malignancies. Methods reviewed 90 implants 27 RT cancer afterwards. The cumulative survival rate (CISR) was calculated. In addition, the quality assessed using “Health Scale Dental Implants.” Results CISR at 3 years 79.6%. mean radiation dose site ( D ) identified as an independent prognostic factor survival. No failed if less than 38 Gy. Regarding quality,...
Purpose To report the results of a correlation analysis skin dose assessed by in vivo dosimetry and incidence acute toxicity. This is phase 2 trial evaluating feasibility intraoperative radiotherapy (IORT) as boost for breast cancer patients. Materials Methods Eligible patients were treated with IORT 20 Gy followed whole irradiation (WBI) 46 Gy. A total 55 minimum follow-up 1 month after WBI evaluated. Optically stimulated luminescence dosimeter (OSLD) detected radiation delivered to during...
130 Background: Somatic mutations of genes involved in DNA repair (e.g. ATM and BRCA1/2) may result chemotherapy resistance poor prognosis, but confer sensitivity to radiation therapy. In this study, we aimed the hypothesis that patients with such be more susceptible radiotherapy. Methods: Using prospectively collected RT registry, identified who underwent both gross disease NGS panel screening between 2013 2019 (N = 27,664). From a cohort 134 patients, 33 somatic mutation or BRCA 1/2 were...
With the introduction of modern sophisticated radiotherapy (RT) techniques, significance accuracy has increased considerably. This study evaluated necessity pre-treatment and intra-fractional cone-beam computed tomography (CBCT) by analyzing inter- CBCT images breast cancer patients receiving RT. From 57 patients, 1206 1067 were collected. Geometric movements measured quantitively in both CBCT, changes dosimetric parameters selected with extreme movement. For right-sided left-sided treated...
Purpose: This study compares the dosimetric properties of EBT3 and EBT4 GAFchromic films in transmission reflection scanning modes, focusing on dose response, sensitivity, postirradiation stability. Methods:The were irradiated at doses 0-10 Gy using a Varian TrueBeam linear accelerator 6 MV.The scanned intervals between 1 336 hours after irradiation both modes.Net optical density (NetOD) values from each scan used to evaluate response with calibration curves created for film mode.Dose...
Abstract BackgroundThe COVID-19 pandemic has stripped many medical students worldwide of their right to quality education. In response, we developed hybrid courses involving aspects both online and in-person teaching for radiation oncology student clerkship.MethodsWe entitled customize own rotation schedule using Google Forms a flipped learning class, which consisted at least one video clip on basic knowledge per day (yonsei-radonc.com). Students were instructed watch videos before the next...
High-throughput mass-spectrometry-based quantitative proteomic analysis was performed using formalin-fixed, paraffin-embedded (FFPE) biopsy samples obtained before treatment from 13 patients with locally advanced rectal cancer (LARC), who were treated concurrent chemoradiation therapy (CCRT) followed by surgery. Patients divided into complete responder (CR) and non-complete (nCR) groups. Immunohistochemical (IHC) staining of 79 independent FFPE tissue to validate the predictive ability...
Prostate-specific antigen (PSA) bounce is common in patients undergoing 125I brachytherapy (BT), and our study investigated its clinical features. A total of 100 who underwent BT were analyzed. PSA large defined as an increase ≥0.2 ≥2.0 ng/mL above the initial nadir, respectively, with a subsequent decline without treatment. Biochemical failure was using Phoenix definition (nadir +2 ng/mL), except for bounce. With median follow-up 49 months, 45% 7% experienced bounce, respectively. The time...
This study aimed to evaluate the quality of low-dose-rate (LDR) prostate brachytherapy (BT) based on treatment-related dosimetric outcomes. Data 100 patients treated using LDR BT with stranded seeds from November 2012 2017 were collected. The prescription dose for was 145 Gy. constraints preoperative plan were: V100% ≥ 95%, V150% ≤ 60%, V200% 20% prostate; rectum, 1 cc; and V200 Gy urethra, 0.0 cc. Intraoperative real-time calculation postoperative distribution analysis days 0 30 performed....