A5036838741- Cholangiocarcinoma and Gallbladder Cancer Studies
- Glioma Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Brain Metastases and Treatment
- Meningioma and schwannoma management
- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Pediatric Hepatobiliary Diseases and Treatments
- AI in cancer detection
- Epilepsy research and treatment
- Endometrial and Cervical Cancer Treatments
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Pharmacological Effects and Toxicity Studies
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Effects of Radiation Exposure
- Testicular diseases and treatments
- Boron Compounds in Chemistry
- Management of metastatic bone disease
CHA Bundang Medical Center
2019-2024
CHA University
2019-2024
Yonsei University
2014-2021
Severance Hospital
2014-2021
Orthopedic Specialty Hospital
2016
Yonsei University Health System
2015
This nationwide, multicenter study investigated treatment outcomes as well the optimal radiotherapeutic strategy in patients with hepatocellular carcinoma (HCC) and portal vein tumour thrombosis (PVTT).We retrospectively reviewed records of 985 who received radiotherapy (RT) for PVTT. The median equivalent RT dose was 48.75 Gy. Combined treatment, defined liver-directed treatments performed within a month RT, administered to 657 (66.7%). PVTT primary were irradiated 413 (41.9%), only...
This study analyzed the outcomes of patients with resected extrahepatic bile duct cancer (EHBDC) in order to clarify role adjuvant treatments these patients.A total 336 EHBDC who underwent curative resection between 2001 and 2010 were retrospectively. The treatment types as follows: surgery alone (n=168), chemotherapy (CTx, n=90), radiotherapy (RT) (n=29), chemoradiotherapy (CRT, n=49).The median follow-up period was 63 months. 5-year rates locoregional failure-free survival (LRFFS), distant...
PurposeEmerging data suggest that higher radiation doses in post-mastectomy radiotherapy may be associated with an increased risk of reconstruction complications. This study aimed to validate previous findings regarding the impact dose on complications among women breast cancer using a multi-center dataset.MethodsFifteen institutions participated, and who received after either autologous or prosthetic were included. The primary endpoint was major post-radiation therapy requiring re-operation...
Purpose This study aimed to evaluate the role of postoperative radiotherapy (PORT) in intracranial solitary fibrous tumor/hemangiopericytoma (SFT/HPC).Materials and Methods A total 133 patients with histologically confirmed HPC were included from eight institutions. Gross resection (GTR) subtotal (STR) performed 86 47 patients, respectively. PORT was 85 (64%). The prognostic effects sex, age, performance, World Health Organization (WHO) grade, location, size, Ki-67, surgical extent, on local...
Background There have been no guidelines for the management of adult patients with diffuse midline glioma (DMG), H3K27M-mutant in Korea since 2016 revised WHO classification newly defined this disease entity.Thus, Korean Society Neuro-Oncology (KSNO), a multidisciplinary academic society, had begun preparing DMG 2019. MethodsThe Working Group was composed 27 medical experts Korea.References were identified through searches PubMed, MEDLINE, EMBASE, and Cochrane CEN-TRAL using specific...
The aim of this study was to evaluate the role radiotherapy (RT) in management Ewing sarcoma family tumors (ESFT).Retrospective analysiswas performed on 91 patientswith localized ESFT treated from 1988 2012. Primary tumor size ≥ 8 cm 33 patients. Surgery, RT, and combined surgery with RT were applied 37, 15, patients, respectively.Median follow-up 43.8 months. Forty-three patients (47.3%) showed recurrence or progressive disease. Twelve (13.2%) local failure after initial treatment....
We assessed the appropriateness of current radiotherapy volume for WHO grade III gliomas. The records 73 patients with gliomas who received postoperative between 2001 and 2013 were retrospectively reviewed. Based on 2016 classification, 25/73 (34.2%) had anaplastic oligodendroglioma (AO), IDH-mutant 1p/19q-codeleted; 11/73 (15.1%) astrocytoma, IDH-mutant; 37/73 (50.7%) IDH-wildtype. extent resection (EOR) was total in 43 (58.9%). median follow-up time 84 months. 5-year overall survival...
Reported incidence of extrahepatic bile duct cancer is higher in Asians than Western populations. Korea, particular, one the countries with highest rates world. Although research and innovative therapeutic modalities for are emerging, clinical guidelines currently unavailable Korea. The Korean Society Hepato-Biliary-Pancreatic Surgery collaboration related societies (Korean Pancreatic Biliary Society, Abdominal Radiology, Medical Oncology, Radiation Pathologists, Nuclear Medicine) decided to...
To investigate the role of radiotherapy (RT) in and to suggest radiotherapeutic strategies for patients presenting with disseminated cervical cancer. We retrospectively analyzed 50 diagnosed as cancer distant lymph nodal or visceral organ metastasis between September 1980 August 2012. Patients were divided into two subgroups according metastasis: 35 node only (group A) 15 B). All received external beam RT pelvis (median dose 45 Gy) high-dose rate intracavitary 30 Gy). Thirty-nine (78%)...
Objective: This study aimed to investigate the segmentation accuracy of organs at risk (OARs) when denoised computed tomography (CT) images are used as input data for a deep-learning-based auto-segmentation framework. Methods: We non-contrast enhanced planning CT scans from 40 patients with breast cancer. The heart, lungs, esophagus, spinal cord, and liver were manually delineated by two experienced radiation oncologists in double-blind manner. AccuContourTM software increase signal...
PurposeTo quantify interobserver variation (IOV) in target volume and organs-at-risk (OAR) contouring across 31 institutions breast cancer cases to explore the clinical utility of deep learning (DL)-based auto-contouring reducing potential IOV.Methods materialsIn phase 1, two were randomly selected distributed multiple for six volumes (CTVs) eight OAR. In Phase 2, auto-contour sets generated using a previously published DL Breast segmentation model made available all participants. The...
The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey diverse queries faced in treatment brain tumors. As part I survey, aim this study is to evaluate national patterns clinical practice about antiepileptic drug (AED) and steroid usage management tumors.A web-based was sent all members KSNO by email. included 9 questions AED 5 tumor patients. All were developed consensus Group.The overall response rate 12.8% (54/423)....
This multicenter retrospective study aimed to investigate clinical, radiologic, and treatment-related factors affecting survival in patients with newly diagnosed diffuse intrinsic pontine glioma (DIPG) treated radiotherapy.Patients aged <30 years who underwent radiotherapy as an initial treatment for DIPG between 2000 2018 were included; did not undergo magnetic resonance imaging at diagnosis those pathologically grade I excluded. We examined medical records of 162 collected from 10...
The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted nationwide questionnaire survey diverse queries facing to treat patients with brain tumor. As part III survey, aim this study is evaluate national patterns clinical practice metastasis and primary central nervous system lymphoma (PCNSL).A web-based was sent all members KSNO by email. included 7 questions 5 PCNSL, focused on management strategies in specific situations. All were developed consensus Group.In...
To evaluate the results of postoperative radiotherapy in patients with extra-hepatic bile duct cancer (EHBDC) and identify prognostic factors for local control survival.Between January 2001 December 2010, we retrospectively reviewed cases 70 EHBDC who had undergone curative resection received radiotherapy. The median radiation dose was 50.4 Gy (range, 41.4 to 54 Gy). margin status R0 30 (42.9%), R1 25 (35.7%), R2 15 (21.4%).The 5-year rates overall survival (OS), event-free (EFS),...
Abstract Our aim was to identify the risk factors associated with locoregional recurrence in resected distal bile duct cancer (DBDC), and determine subgroup that may benefit from adjuvant radiotherapy. Between 2001 2013, we retrospectively analyzed 93 patients DBDC who had undergone curative resection. Patients received radiotherapy were excluded. The 3-year failure-free survival (LRFFS) overall (OS) rates for all 50.7%, 53.2%, respectively. On multivariate analysis, preoperative...
Human pluripotent stem cells (PSCs) through somatic cell nuclear transfer (SCNT) may be an important source for regenerative medicine. The low derivation efficiency of and the accessibility human oocytes are main obstacles to their application. We previously reported that SCNT was increased by overexpression H3K9me3 demethylase. Here, we applied a modified method PSC line first obtained SCNT-PSC lines derived from both donated cryopreserved cord blood with homozygous leukocyte antigen (HLA)...
The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey diverse queries faced in treatment brain tumors. As part II survey, aim this study is to evaluate national patterns clinical practice patients with diffuse midline glioma and meningioma.A web-based was sent all members KSNO by email. included 4 questions 6 meningioma (including 2 case scenarios). All were developed consensus Group.In about glioma, 76% respondents performed...