A5101894961- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Cancer-related gene regulation
- Plant Molecular Biology Research
- Agronomic Practices and Intercropping Systems
- Photosynthetic Processes and Mechanisms
- Antimicrobial Peptides and Activities
- Plant Stress Responses and Tolerance
- HER2/EGFR in Cancer Research
- Growth and nutrition in plants
- Cancer Treatment and Pharmacology
- Lipid metabolism and biosynthesis
- Soil Management and Crop Yield
- Agriculture, Soil, Plant Science
- Biochemical and Molecular Research
- Hibiscus Plant Research Studies
- Plant Pathogens and Resistance
- Radiopharmaceutical Chemistry and Applications
- Enzyme Catalysis and Immobilization
- Plant Disease Resistance and Genetics
- Plant Reproductive Biology
- Circular RNAs in diseases
- Polysaccharides and Plant Cell Walls
- Aluminum toxicity and tolerance in plants and animals
- Mycorrhizal Fungi and Plant Interactions
Beijing Forestry University
2025
State Forestry and Grassland Administration
2025
Guangxi University
2023-2024
Qilu Hospital of Shandong University
2022-2024
Nanjing Tech University
2023
China Agricultural University
2010-2022
Hunan Agricultural University
2022
Institute of Plant Protection
2017
China Medical University
2013
Chinese Academy of Medical Sciences & Peking Union Medical College
2012
Trichomes, the hair-like structures located on aerial parts of most vascular plants, are associated with a wide array biological processes and affect economic value certain species. The involved in unicellular trichome formation have been well-studied Arabidopsis (Arabidopsis thaliana). However, our understanding morphological changes underlying molecular multicellular development is limited. Here, we studied dynamic developmental glandular nonglandular cucumber (Cucumis sativus L.) divided...
This study investigates the effects of gender and developmental stage on photosynthetic nitrogen allocation in 10-year-old Fraxinus velutina Torr. focusing leaf nitrogen. The results reveal significant differences patterns between genders stages (p < 0.05 for gender, p 0.01 stages). Male trees generally exhibit higher use efficiency (PNUE) rate (Pphot) than female trees. However, allocate more to processes (Rubisco bioenergetics) during fruit expansion compensate reproductive costs....
Sixty specific-pathogen-free chickens were randomly divided into 2 groups (30 for each group) to determine the effect of swine gut antimicrobial peptides (SGAMP) on intestinal mucosal immunity. All raised in negative-pressure isolators and fed same diet. The results as follows. (1) In SGAMP group, number mast cells was increased markedly duodenum from d 21 49 (P < 0.05), similar observed jejunum ileum after being treated with 0.05). However, fewer those tissues control. (2) Intraepithelial...
Replant disease caused by continuous cropping obstacles commonly occurs in a Lilium brownii consecutive monoculture. To reveal the mechanisms contributing to of L. brownii, four patterns (fallow, brownii-rice rotation, newly planted and 2-year monoculture) were designed, Illumina MiSeq (16S rDNA ITS) was utilized detect shifts microbial community rhizosphere. Our result showed that planting significantly reduced soil pH. Consecutive monoculture can decrease diversity abundance bacteria, but...
Infectious bronchitis virus (IBV), the causative agent of infectious bronchitis, results in respiratory disease, nephritis, and poor egg production quality chicken. Antimicrobial peptides possess potent antimicrobial activities are regarded as promising therapeutic alternatives fight against microorganisms. To assess vitro antiviral activity swine intestine (SIAMP) IBV, 45 chick embryos were randomly assigned into 3 groups, 15 for each group. Embryos group 1 inoculated with IBV. Group 2 was...
A new disease of strawberry (Fragaria ananassa Duch.) was discovered in the Lianqiao planting base Shaodong County, Hunan Province, China. In early stage, leaves showed small black spots surrounded by yellow halos, while late a white fluffy layer mold appeared. Fruits were covered with mold. The symptoms observed using vitro inoculation experiments. After spray-inoculation stabbed leaves, halos occurred on no clear boundary between diseased and healthy areas. gradually expanded formed under...
This study aims to identify whether the specialty-oriented case-based learning (CBL) pedagogy contributes teaching of basic theory and practical operation in undergraduate clinical pediatric surgery, assess satisfaction undergraduates.A total 72 undergraduates Grade 2016 who interned at Qilu Hospital Shandong University were enrolled this study. All these voluntarily participated experimental They randomly divided into group (the CBL group, n = 36) control [the traditional lecture-based...
To evaluate the efficacy, safety and survival of combination carboplatin plus paclitaxel as neoadjuvant chemotherapy (NACT) for patients with locally advanced triple-negative breast cancer (TNBC), explore an optimal regimen TNBC.Patients core needle biopsy confirmed pathological diagnosis IIA ∼ IIIC invasive cancer, negative estrogen progesterone receptors HER2 by immunohistochemistry, indication NACT were eligible in this study. The tumor tissues tested CK5/6, CK14, EGFR Ki67. received 175...
Objective This study was conducted to explore the risk factors for prognosis and recurrence of ureteropelvic junction obstruction (UPJO). Methods The correlation these variables with risks analyzed by binary multivariate logistic regression. Besides, a nomogram constructed based on regression calculation. After model verified C-statistic, ROC curve plotted evaluate sensitivity model. Finally, decision analysis (DCA) estimate clinical benefits losses intervention measures under series...
Abstract Background: AKT inhibitor was reported to be a potential treatment for drug-resistant tumors by reducing activity, and synergistic agent of ICIs. Afuresertib is an oral pan-AKT that has shown clinical efficacy in multiple tumors. The phase I part this study assessed the safety, tolerability, anti-tumor activity combination therapy LAE005 (PD-L1 antibody) plus afuresertib nab-paclitaxel advanced solid tumors, primarily TNBC. Methods: This multi-center, open-label, dose-escalation...
Bama County is a world-famous longevity county in the Guangxi Province, China. hemp traditional seed used cultivation County. The seeds contain abundant unsaturated fatty acids, particularly linoleic acid (LA) and linolenic golden ratio. These two substances have been proven to be related human health prevention of various diseases. However, development oil accumulation mechanisms remain unclear. This study employed combined analysis physiological, transcriptomic, metabolomic parameters...
<title>Abstract</title> <bold>Aims and Background</bold> The growing human population scarcity of new arable land necessitate exploring contaminated lands for agriculture production. Intercropping, a strategic method involving different plant species to enhance biomass, soil health phytoremediation, thus promoting sustainable agricultural practices on lands. Therefore, the selection suitable intercropping systems is great interest agriculture. <bold>Methods</bold> This research focused...
Abstract Background To explore the potential role of m6A methylation modification in Wilms Tumor (WT) by m6A-RNA Methylation (m6A) regulators. Methodology The association patterns with immune and prognostic characteristics tumors was systematically evaluated using 19 regulators extracted from Tumor’s samples public databases. A comprehensive model “m6Ascore” constructed principal component analysis, its value evaluated. Results Almost all were differentially expressed between WT normal...
CD34+cells differentiated from mesenchymal stem cells (MSCs) have a strong biological function in cardiovascular regeneration. However, the molecular mechanisms of and methods to improve CD34+ cell differentiation MSCs, especially human MSCs (hUC-MSCs) are still unclear. In current study, effect CD34 antibody on umbilical cord (UC)-derived is determined. The results demonstrated that expression cd34 protein significantly increased hUC-MSCs treated with antibody. addition, proliferation after...
Abstract Background. To explore the potential role of m6A methylation modification in Wilms Tumor (WT) by m6A-RNA Methylation (m6A) regulators. Methodology. The association patterns with immune and prognostic characteristics tumors was systematically evaluated using 19 regulators extracted from Tumor’s samples public databases. A comprehensive model "m6Ascore" constructed principal component analysis, its value evaluated. Results. Almost all were differentially expressed between WT normal...
Abstract Background: Wilms tumor (WT), which is the most common malignancy of genitourinary system in children. Cuproptosis a unique form cell death, and mechanism interaction with WT not yet clear. This study aims at using bioinformatics technology to construct prognostic signature identify cuproptosis-related biomarkers improve prognosis treatment WT. Methods: RNA sequencing clinical data were downloaded from TARGET database. The lncRNAs screened by Pearson's correlation calculation,...