Chunyan Guo

ORCID: 0000-0003-3193-5418
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Neonatal and Maternal Infections
  • Respiratory Support and Mechanisms
  • Streptococcal Infections and Treatments
  • Wastewater Treatment and Nitrogen Removal
  • Advanced Computational Techniques and Applications
  • Web Applications and Data Management
  • Software Engineering and Design Patterns
  • Traditional Chinese Medicine Analysis
  • Ocular Surface and Contact Lens
  • Surface Chemistry and Catalysis
  • Plant-based Medicinal Research
  • Liver physiology and pathology
  • Antimicrobial Peptides and Activities
  • Asthma and respiratory diseases
  • Ocular Infections and Treatments
  • Online Learning and Analytics
  • Neonatal and fetal brain pathology
  • Brain Tumor Detection and Classification
  • Cardiac Ischemia and Reperfusion
  • Innovation in Digital Healthcare Systems
  • Antifungal resistance and susceptibility
  • Graphene and Nanomaterials Applications
  • Artificial Intelligence in Healthcare

Shandong First Medical University
2021-2025

Shandong Provincial Hospital
2021-2025

Jinzhong University
2024

Hebei North University
2015-2023

Creative Commons
2021

Inner Mongolia Medical University
2019-2021

University of Jinan
2009-2021

Chaohu Hospital of Anhui Medical University
2021

Weatherford College
2021

Temple University
2020

Nowadays, Heart disease is one of the crucial impacts mortality in country. In clinical data analysis, predicting cardiovascular a primary challenge. Deep learning (DL) has been demonstrated to be effective helping determine and forecast huge amount produced by health industry. this paper, proposed Recursion enhanced random forest with an improved linear model (RFRF-ILM) detect heart disease. This paper aims find key features prediction diseases through use machine techniques. The adding...

10.1109/access.2020.2981159 article EN cc-by IEEE Access 2020-01-01

Objective: To evaluate the efficacy and safety of rivaroxaban investigate clinical features Mycoplasma pneumoniae pneumonia (MPP) associated with pulmonary thromboembolism (PTE) in children. Methods: A case series study was conducted on 36 children, diagnosed MPP PTE hospitalized our institution from January 2020 to June 2024 Department Pediatric Respiratory, Shandong Provincial Hospital Affiliated First Medical University. Clinical data follow-up information were collected analyze their...

10.3760/cma.j.cn112140-20241202-00881 article EN PubMed 2025-03-17

Objectives: The incidence of psychological and behavioral problems depression among adolescents is increasing year by year, which has become an important public health problem. Alexithymia, as susceptible factor adolescent depression, may continue to develop strengthen under the stimulation COVID-19-related stressors. However, no studies have focused on alexithymia in during pandemic China. This study aims investigate related factors pandemic. Methods: Three hundred patients were enrolled...

10.3389/fpsyt.2021.774952 article EN cc-by Frontiers in Psychiatry 2021-11-22

In recent years, nanomaterial-based drug delivery carriers have become some of the most attractive to be studied. The purpose this study is investigate interaction C60 fullerene, carbon nanotube and graphene having porphyrin-like FeN4 clusters with a non-steroidal anti-inflammatory (ibuprofen) by means density functional theory. Results showed that could remarkably increase tendency for adsorption ibuprofen drug. Also, our ultraviolet–visible results show electronic spectra complexes exhibit...

10.1080/00268976.2019.1678776 article EN Molecular Physics 2019-10-17

Microwave-assisted extraction was used for the of alantolactone and isoalantolactone from Inula helenium. Effects various experimental factors including ethanol concentration, particle size, microwave radiation time, ratio material to liquid temperature on yield were evaluated. The optimal extracting process root helenium 1 g plant sample (sifted through 140 mesh) mixed with 15 ml 80% solution, 120 s at 50°. Under these conditions, 31.83±2.08 mg/g 21.25±1.37 mg/g, respectively. Compared heat...

10.4103/0250-474x.151594 article EN Indian Journal of Pharmaceutical Sciences 2015-01-01

J2EE model and technology, the concept structure of MVC pattern, are introduced in this paper. Based on four-tier architecture a technology roadmap e-commerce system is planned out: JSP plus Servlet Session Bean CMP database, which makes up shortcomings unclear business logic among tiers J2EE, simplifies development process, can develop stronger with scalability maintainability. Finally, realistic put forward roadmap, further demonstrates our conclusion research.

10.1109/icmecg.2009.107 article EN International Conference on Management of e-Commerce and e-Government 2009-01-01

Combining density functional theory and high-resolution NC-AFM experiments, we have studied the on-surface reaction mechanisms responsible for covalent dimerization of 4-iodobenzoic acid (IBA) organic molecules on calcite (10.4) insulating surface. When annealed at 580 K, assemble in one-dimensional chains covalently bound dimers. The a unique orientation result from complex set processes, including nominally rather costly double dehalogenation followed by dimerization. First, focusing...

10.1021/acs.jpcc.7b02687 article EN The Journal of Physical Chemistry C 2017-04-12

Obstructive jaundice (OJ) could seriously affect the biochemical and immune functions in body. Up to now, there are still poor evidences about role of dexmedetomidine OJ. Male Wistar rats were divided into four groups: Sham operation group (Sham group, n = 10), obstructive (OJ OJ + (D OJ+ +LY294002 (DL 10). The expressions phospho-Akt(p-Akt), HIF-1α(hypoxia inducible factor-1α), Akt mRNA, HIF-1αmRNA, interleukin-6 (IL-6) tumor necrosis factor-α (TNF-α) different groups evaluated. lung injury...

10.1016/j.arcmed.2019.08.006 article EN cc-by-nc-nd Archives of Medical Research 2019-07-01

Anesthesia signal monitoring is a very important indicator in surgery, and the effective of anesthesia depth has been goal anesthesiologists biomedical engineering experts recent decades. First, wavelet transform method used to analyze EEG signals, extracted features are clustered by classifier estimate anesthesia. Second, characteristics eigenvectors constructed singular value decomposition based on coefficients. The extraction extracts mid-latency auditory evoked under Finally, this paper...

10.1109/access.2019.2907794 article EN cc-by-nc-nd IEEE Access 2019-01-01

Abstract Rationale: Mucormycosis is a rare fungal infection that typically occurs in immunosuppressed patients following chemotherapy or hematopoietic stem cell transplantation. Patient concerns: An 11-year-old child with newly developed acute lymphoblastic leukemia suffered from the paroxysmal left chest pain, fever, and hemoptysis. Diagnoses: We made histopathologic diagnosis aided by bronchoscopy techniques, which indicated invasive hyphae are characteristic of mucormycosis....

10.1097/md.0000000000024630 article EN cc-by-nc Medicine 2021-02-12

Obstructive jaundice (OJ) is a common disease in clinical surgery. The present study aimed to determine the effects of dexmedetomidine (Dex) on hepatocyte apoptosis rats with OJ and also explore underlying mechanism. A total 30 adult male Sprague Dawley were randomly divided into 3 groups: Sham group, bile duct ligation (BDL) BDL+Dex group. serum liver function index, expression levels inflammatory factor interleukin-6 (IL-6) tumor necrosis factor-α (TNF-α), pathological changes compared...

10.3892/etm.2019.8085 article EN Experimental and Therapeutic Medicine 2019-10-08

Two new arsenic–vanadate compounds [Co(C4H13N3)2]2[As8V14O42(H2O)] · 3.5H2O (1) and (C2N2H9)2(C2N2H10)[As8V14O42(H2O)] 2.33H2O (2) have been hydrothermally synthesized characterized by X-ray single crystal diffraction, IR spectra thermogravimetric analysis. Compound 1 crystallizes in the monoclinic space group P 2(1)/c, a = 24.649(9) Å, b 13.364(5) c 22.463(8) β 104.008(5)°, V 7180(5) Å3, Z 4, R 0.0787, wR 2 0.1859. rhombohedral system with R3c, 22.2405(5) α γ 110.4030(10)°, 8163.4(3) 6,...

10.1080/00958970701323996 article EN Journal of Coordination Chemistry 2008-01-20

The microbiological and biochemical characteristics of enhanced biological phosphorus removal (EBPR) process was summarized. With respect to the microbiology, competition relationship among main microbes in system, including poly-phosphate accumulating organisms (PAOs), glycogen (GAOs) denitrified PAOs (DPAOs) were concluded. A wide variety separated from EBPR system Accumulibacter considered a typical PAO, existing all kinds systems. There still controversy concerning between GAOs...

10.3724/sp.j.1145.2011.00427 article EN Chinese Journal of Appplied Environmental Biology 2012-02-01

Yeast peptides, which are small-molecule active peptides extracted from yeast proteins, known for their antibacterial, antioxidant, and anti-inflammatory properties. However, the effects of peptide on suckling calves remain unclear. In this study, supplementation growth, diarrhea incidence, immune function during period were determined. Thirty newborn randomly divided into two groups: control group (CON) treatment (AP), received fresh pasteurized milk supplemented with (5 g/day). The...

10.3389/fvets.2024.1454839 article EN cc-by Frontiers in Veterinary Science 2024-10-10

Objective: To compare predictive value of the current 7 scoring systems and CADILLAC-plus system for risk short-term deathin patients with acute myocardial infarction complicating cardiogenic shock. Methods: A total 126 shock hospitalized in Fuwai hospital from June 2014 to January 2018 were enrolled this study, clinical data retrospectively analyzed. The divided into survival group(49 cases) death group(77 according or not at 28 days after diagnosis shock.The scores APACHE Ⅱ,APACHE Ⅲ,SAPS...

10.3760/cma.j.issn.0253-3758.2018.07.005 article EN PubMed 2018-07-24

In the paper, architecture of J2EE and method development system with were described. Among these technologies, Web application MVC model to develop was emphasized. On base B2B business trade flow, requirement analysis discussed in detail. It emphasized that modeling designed implemented. A e-commerce four-layer by EJB component technology established. Key words: E-Commerce system; technology; component;

10.3968/j.mse.1913035x20100404.014 article EN International Conference on Management Science and Engineering 2011-01-19

Objective. To uncover the protective role of sevoflurane on hypoxia/reoxygenation-induced cardiomyocyte apoptosis through protein kinase B (Akt) pathway. Methods. An in vitro hypoxia/reoxygenation (H/R) model was established cell line H9c2. Sevoflurane (SEV) administrated H9c2 cells during reoxygenation period. Viability, layered double hydroxide (LDH) release, and were determined to assess H/R-induced damage. Relative levels apoptosis-associated genes examined. Moreover, phosphorylation Akt...

10.1155/2021/4114593 article EN Disease Markers 2021-12-07

Congenital pulmonary arteriovenous fistulae occur as a result of abnormal blood vessel development in the lungs. Blood takes short pass from artery to veins. Multiple are rare occurrence, especially when involving both Fistulae located at edge prone rupture and bleeding. We discuss case 15-year-old overweight male with multiple successfully treated wedge-shape excision via video-assisted thoracoscopic surgery.

10.1111/1759-7714.12781 article EN cc-by-nc Thoracic Cancer 2018-06-23

Parkinson's disease (PD) is a complex multifactorial neurodegenerative disease, and PD the second most common after Alzheimer's disease. Studies have shown that paeoniflorin (PF) has neuroprotective effect, but specific mechanism target need to be further studied. Network pharmacology combined molecular docking one of important methods discover drug action. In this study, 1160 targets been obtained by using TTD database, DisGeNET database DrugBank database. TCMSP was used query PF chemical...

10.2139/ssrn.4394185 article EN 2023-01-01
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